STMN2

Gene Symbol STMN2
Entrez Gene 11075
Alt Symbol SCG10, SCGN10
Species Human
Gene Type protein-coding
Description stathmin 2
Other Description neuron-specific growth-associated protein|neuronal growth-associated protein (silencer element)|stathmin-2|stathmin-like 2|superior cervical ganglia, neural specific 10|superior cervical ganglion-10 protein
Swissprots O14952 Q6PK68 G3V110 A8K9M2 Q93045
Accessions EAW87063 EAW87064 EAW87065 Q93045 AI096716 AK091336 AK292737 BAF85426 AK297485 BAH12589 AK297594 BAH12622 AK299500 BAH13053 AK308557 AK309130 AL110174 BC006302 AAH06302 BQ069488 BT020034 AAV38837 CR456833 CAG33114 D50375 BAA23326 DC319376 DQ892719 ABM83645 DQ895968 ABM86894 S82024 AAB36428 XM_005251142 XP_005251199 NM_001199214 NP_001186143 NM_007029 NP_008960
Function Regulator of microtubule stability. When phosphorylated by MAPK8, stabilizes microtubules and consequently controls neurite length in cortical neurons. In the developing brain, negatively regulates the rate of exit from multipolar stage and retards radial migration from the ventricular zone (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm {ECO:0000250}. Cytoplasm, perinuclear region {ECO:0000250}. Cell projection, growth cone. Membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Cell projection, axon. Golgi apparatus. Endosome {ECO:0000250}. Cell projection, lamellipodium. Note=Associated with punctate structures in the perinuclear cytoplasm, axons, and growth cones of developing neurons. SCG10 exists in both soluble and membrane-bound forms. Colocalized with CIB1 in neurites of developing hippocampal primary neurons (By similarity). Colocalized with CIB1 in the cell body, neuritis and growth cones of neurons. Colocalized with CIB1 to the leading edge of lamellipodia. {ECO:0000250}.
Tissue Specificity Neuron specific.

SCG10 (P-15) - sc-49258 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

SCG10 (2-RE19) - sc-135620 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
SCG10 (2-RE19): sc-135620. Western blot analysis of SCG10 expression in human SCG10 transfected (A) and non-transfected (B) 293T whole cell lysates.

Anti-STMN2 antibody - ab104560 from Abcam

Prices $390.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab104560 staining STMN2 in rat glioblastoma cell line C6 by Immunocytochemistry/ Immunofluorescence.Cells were fixed in paraformaldehyde, permeabilized using 0,1% Triton X 100 in PBS, blocked with 0.5% BSA for 30 minutes at room temperature and then incubated with ab104560 at a 1/50 dilution for 16 hours at 4°C. The secondary used was a Cy3 conjugated goat anti-rabbit polyclonal used at a 1/400 dilution. Nuclei are counterstained with DAPI.See Abreview

Anti-STMN2 antibody - ab21190 from Abcam

Prices $378.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Anti-STMN2 antibody (ab21190) at 1 µg/ml + Human Brain lysate (RIPA buffer, 35µg total protein per lane).

Anti-STMN2 antibody - ab56888 from Abcam

Host Mouse
Clonality Monoclonal
Western blot against tagged recombinant protein immunogen using ab56888 STMN2 antibody at 1ug/ml.

Anti-STMN2 antibody [EPR15286] - ab185943 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR15286
Immunoprecipitation of Human fetal brain lysate labelling STMN2 with ab185943 at 1/50 dilution (Lane 1) compared to control PBS (lane 2).  Anti-Rabbit IgG (HRP), specific to the non-reduced form of IgG secondary antibody used at 1/1500 dilution.

Anti-STMN2 antibody [EPR15286-39] - ab185956 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR15286-39
All lanes : Anti-STMN2 antibody [EPR15286-39] (ab185956) at 1/20000 dilutionLane 1 : Human fetal brain lysatesLane 2 : SH-SY5Y cell lysatesLane 3 : Rat brain lysatesLysates/proteins at 10 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Anti-STMN2 antibody - N-terminal - ab202316 from Abcam

Prices $359.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-STMN2 antibody - N-terminal (ab202316) at 1/1000 dilutionLane 1 : U-87 MG cell lysateLane 2 : SH-SY5Y cell lysateLane 3 : Human brain tissue lysateLane 4 : Mouse brain tissue lysateLane 5 : Rat brain tissue lysateLysates/proteins at 35 µg per lane.SecondaryGoat anti-rabbit IgG H&L(HRP) at 1/10000 dilution

Anti-SCG10 / STMN2 Antibody (aa1-90) - LS-C126332 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-SCG10 / STMN2 Antibody (aa145-173, AP) - LS-C270589 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SCG10 / STMN2 Antibody (aa145-173, APC) - LS-C270590 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SCG10 / STMN2 Antibody (aa145-173, Biotin) - LS-C270591 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SCG10 / STMN2 Antibody (aa145-173, FITC) - LS-C270592 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SCG10 / STMN2 Antibody (aa145-173, Azide-free, HRP) - LS-C270593 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SCG10 / STMN2 Antibody (aa145-173, PE) - LS-C270595 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SCG10 / STMN2 Antibody (aa134-179) - LS-C313967 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SCG10 / STMN2 Antibody (aa144-173) - LS-C325460 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SCG10 / STMN2 Antibody (aa145-173) - LS-C161571 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
STMN2 Antibody western blot of Jurkat cell line lysates (35 ug/lane). The STMN2 antibody detected the STMN2 protein (arrow).

Anti-SCG10 / STMN2 Antibody (aa26-179, clone 684433) - LS-C150118 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 684433
Stathmin-2/STMN2 in Human Liver. Stathmin-2/STMN2 was detected in immersion fixed paraffin-embedded sections of human liver using Mouse Anti-Human Stathmin-2/STMN2 Monoclonal Antibody at 15 ug/ml overnight at 4°C. Tissue was stained using Anti-Mouse HRP-DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to hepatocytes.

Anti-SCG10 / STMN2 Antibody (aa36-69) - LS-C344419 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of lysates from U-87 MG, SH-SY5Y cell line, human brain, mouse brain, rat brain tissue lysate (from left to right) with STMN2 Antibody. Antibody was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L (HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 35 ug per lane.

Anti-SCG10 / STMN2 Antibody (C-Terminus) - LS-C143454 from LifeSpan Bioscience

Prices $335.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
STMN2 Antibody - Staining of STMN2 in HEK293T cells transfected with GFP or a GFP-STMN2 fusion. Antibody was used at a dilution of 1:1000 (A, B) and 1:3000 (C).

Anti-SCG10 / STMN2 Antibody (aa2-11) IHC-plus™ - LS-B3285 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-STMN2 antibody IHC of human small intestine, myenteric plexus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3285 concentration 5 ug/ml.

Anti-SCG10 / STMN2 Antibody (aa2-41) - LS-C185808 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
STMN2 antibody detects STMN2 protein at cytoplasm on Liver carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded Liver carcinoma. STMN2 antibody dilution:1:250.

Stathmin-2/STMN2 Antibody - NBP1-49461 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Stathmin-2/STMN2 Antibody [NBP1-49461] -  Analysis of endogenous STMN2 in mouse dorsal root ganglia (DRG) neurons.  A partial siRNA knockdown was used in the second lane.  NBP1-49461 was used at a dilution of 1:1000.  Image courtesy of Dr. Jung Eun Shin.

Stathmin-2/STMN2 Antibody (684433) [Unconjugated] - MAB6930 from Novus Biologicals

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Mouse
Clonality Monoclonal
Clone 684433
Western blot shows lysates ofSH‑SY5Y human neuroblastoma cell line. PVDF membrane was probed with 0.05 µg/mL of Mouse Anti-Human Stathmin‑2/STMN2 Monoclonal Antibody (Catalog # MAB6930) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF007). For additional reference, recombinant human Stathmin‑1 and recombinant humanStathmin‑2 (20 ng/lane) were included. A specific band was detected for Stathmin‑2/STMN2 at approximately 25 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.
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