Gene Symbol | Hemgn |
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Entrez Gene | 93966 |
Alt Symbol | 4921524M03Rik, AI317176, EDAG, Hgn, mNDR |
Species | Mouse |
Gene Type | protein-coding |
Description | hemogen |
Other Description | hemopoietic gene protein|negative differentiation regulator protein|nuclear protein |
Swissprots | Q80YT2 Q3TAE6 B1AVH8 Q9ERZ0 Q8CF29 |
Accessions | ABB17039 EDL02369 EDL02370 Q9ERZ0 AF269248 AAG33367 AK006588 BAC25148 AK076587 AK077692 BAC36959 AK156536 BAE33747 AK171890 BAE42722 AK171906 AK172421 AY699986 AAT94243 BC050798 AAH50798 XM_011250137 XP_011248439 NM_053149 NP_444379 |
Function | Regulates the proliferation and differentiation of hematopoietic cells. Overexpression block the TPA-induced megakaryocytic differentiation in the K562 cell model. May also prevent cell apoptosis through the activation of the nuclear factor-kappa B (NF-kB) (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:11404085}. |
Tissue Specificity | Expressed in hematopoietic precursor cells. Highly expressed in bone marrow, the red pulp of the spleen and round spermatids. Weakly expressed in peripheral blood cells. {ECO:0000269|PubMed:11404085, ECO:0000269|PubMed:14648837}. |
Recombinant Mouse Hemogen(Hemgn) - CSB-YP010284MO CSB-EP010284MO CSB-BP010284MO CSB-MP010284MO from Cusabio
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Recombinant Mouse HEMGN Protein - HEMGN-7571M from Creative Biomart
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Hemogen (Hemgn), Recombinant Protein - MBS1430631 from MyBioSource
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