Gene Symbol | IFI30 |
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Entrez Gene | 10437 |
Alt Symbol | GILT, IFI-30, IP-30, IP30 |
Species | Human |
Gene Type | protein-coding |
Description | interferon, gamma-inducible protein 30 |
Other Description | gamma-interferon-inducible lysosomal thiol reductase|gamma-interferon-inducible protein IP-30|interferon gamma-inducible protein 30 preproprotein|legumaturain |
Swissprots | Q8WU77 Q76MF9 P13284 Q9UL08 Q8NEI4 |
Accessions | AAD22672 EAW84661 EAW84662 EAW84663 EAW84664 EAW84665 EAW84666 P13284 AB049659 BAC98466 AF097362 AAF04618 AF401212 AAL02170 AI022513 AK123477 AK291551 BAF84240 AL558891 BC021136 AAH21136 BC031020 AAH31020 BE515053 DQ884410 ABI63377 DQ892016 ABM82942 DQ895206 ABM86132 NM_006332 NP_006323 |
Function | Lysosomal thiol reductase that can reduce protein disulfide bonds. May facilitate the complete unfolding of proteins destined for lysosomal degradation. Plays an important role in antigen processing. Facilitates the generation of MHC class II- restricted epitodes from disulfide bond-containing antigen by the endocytic reduction of disulfide bonds (By similarity). Facilitates also MHC class I-restricted recognition of exogenous antigens containing disulfide bonds by CD8+ T-cells or crosspresentation (By similarity). {ECO:0000250}. |
Subcellular Location | Secreted. Lysosome. |
Top Pathways | Antigen processing and presentation |
Human IFI30 full length protein - ab134622 from Abcam
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IFI30 / IP30 Antibody Blocking Peptide - LS-E23463 from LifeSpan Bioscience
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GILT/IFI30 Recombinant Protein - H00010437-P01 from Novus Biologicals
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Recombinant Human GILT/IFI30 Protein - NBP2-23146 from Novus Biologicals
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IFI30-Antibody-C-term-Blocking-Peptide - BP9517b from Abgent, a WuXi AppTec company
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Human IFI30 protein - orb168544 from Biorbyt
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Human IFI30 protein (His Tag) - orb139037 from Biorbyt
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IFI30 protein (His tag) - 80R-2505 from Fitzgerald
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IFI30 / GILT (58-232, His-tag) - AR50577PU-N from Acris Antibodies
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IFI30 / GILT (58-232, His-tag) - AR50577PU-S from Acris Antibodies
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IFI30 / GILT - H00010437-P01-10 from Acris Antibodies
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IFI30 / GILT - H00010437-P01-25 from Acris Antibodies
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IFI30, 58-232aa, Human, His tag, E.coli - 01-P1753 from ARP American Research Products
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IFI30 fusion protein - Ag2178 from Proteintech Group
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IFI30 Human - CYPS-190 from NeoScientific
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Recombinant Human IFI30, GST-tagged - IFI30-14061H from Creative Biomart
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Recombinant Human Interferon, Gamma-Inducible Protein 30, His-tagged - IFI30-7185H from Creative Biomart
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Recombinant Interferon Gamma Inducible Protein 30 (IFI30) - RPE762Hu01 from Uscn Life Science Inc.
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Human IFI30 Protein (His Tag) - 12623-H08H-20 from Sino Biological
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Recombinant Interferon Gamma Inducible Protein 30 (IFI30) - RPE762Hu01 from Cloud-clone
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Recombinant Human Gamma-interferon-inducible lysosomal thiol reductase(IFI30) - CSB-YP011012HU CSB-EP011012HU CSB-BP011012HU CSB-MP011012HU from Cusabio
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IFI30, 58-232aa, Human, His tag, E.coli - ATGP1753 from ATGen
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IFI30 / GILT - TP305877 from Acris Antibodies
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IFI30 fusion protein - Ag25137 from Proteintech Group
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Recombinant Human IFI30 Protein (His tag) - PKSH030801 from Elabscience
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