BHLHA15

Gene Symbol BHLHA15
Entrez Gene 168620
Alt Symbol BHLHB8, MIST1
Species Human
Gene Type protein-coding
Description basic helix-loop-helix family, member a15
Other Description MIST-1|basic helix-loop-helix domain containing, class B, 8|class A basic helix-loop-helix protein 15|class B basic helix-loop-helix protein 8|class II bHLH protein MIST1|muscle, intestine and stomach expression 1
Swissprots A4D271 Q14DE4 Q7RTS1
Accessions EAL23893 Q7RTS1 BC113394 AAI13395 BC113396 AAI13397 BK000276 DAA01056 BX648200 NM_177455 NP_803238
Function Plays a role in controlling the transcriptional activity of MYOD1, ensuring that expanding myoblast populations remain undifferentiated. Repression may occur through muscle-specific E- box occupancy by homodimers. May also negatively regulate bHLH- mediated transcription through an N-terminal repressor domain. Serves as a key regulator of acinar cell function, stability, and identity. Also required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport. May function as a unique regulator of gene expression in several different embryonic and postnatal cell lineages. Binds to the E- box consensus sequence 5'-CANNTG-3' (By similarity). {ECO:0000250|UniProtKB:Q9QYC3}.
Subcellular Location Nucleus {ECO:0000305}.
Tissue Specificity Expressed in brain, liver, spleen and skeletal muscle. {ECO:0000269|PubMed:14516699}.
Top Pathways Maturity onset diabetes of the young

MIST1/bHLHa15 (D7N4B) XP ® Rabbit mAb - 14896 from Cell Signaling Technology

Prices $109.00, $277.00
Sizes 20 µl (2 western blots), 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D7N4B
Western blot analysis of extracts from human pancreas, mouse pancreas, and human colon using MIST1/bHLHa15 (D7N4B) XP ® Rabbit mAb (upper) and β-Actin (D6A8) Rabbit mAb #8457 (lower).

MIST1 (A-6) - sc-166181 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
MIST1 (A-6): sc-166181. Western blot analysis of MIST1 expression in MIA PaCa-2 whole cell lysate.

MIST1 (6E8) - sc-80984 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
MIST1 (6E8): sc-80984. Western blot analysis of MIST1 expression in MIST1KO mouse (A)and MIST1WT mouse (B) pancreas tissue extracts. Kindly provided by Daniel DiRenzo and Stephen Konieczny, Purdue University.

MIST1 (C-18) - sc-324133 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
MIST1 (C-18): sc-324133. Western blot analysis of MIST1 expression in Jurkat (A), K-562 (B), NIH/3T3 (C), Neuro-2A (D) and MIA PaCa-2 (F) whole cell lysates and mouse liver tissue extract (E).

MIST1 (N-17) - sc-324131 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

MIST1 (H-50) - sc-98771 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-BHLHA15 antibody - ab180889 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-BHLHA15 antibody (ab180889) at 1 µg/mlLane 1 : Rat small intestine tissue lysateLane 2 : Rat small intestine tissue lysate with blocking peptideLysates/proteins at 15 µg per lane.

Anti-BHLHA15 antibody - ab107390 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-BHLHA15 antibody (ab107390) at 1/100 dilution + U251 cell line lysates at 35 µg

Anti-BHLHA15 antibody - ab187978 from Abcam

Prices $443.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded Human pancreas tissue labeling BHLHA15 with ab187978 at 1/200 dilution.

Anti-BHLHA15 antibody [1H1/E5/E5] - ab111924 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1H1/E5/E5

Anti-BHLHA15 antibody [6E8/A12/C11P1] - ab110919 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 6E8/A12/C11P1
ab110919 staining BHLHA15 in paraffin-embedded Mouse pancreas tissue by Immunohistochemistry. Note: nuclear staining in acinar cells but not in duct or islet cells.

Anti-BHLHA15 Antibody (aa160-189, AP) - LS-C252959 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BHLHA15 Antibody (aa160-189, APC) - LS-C252960 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BHLHA15 Antibody (aa160-189, Biotin) - LS-C252961 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BHLHA15 Antibody (aa160-189, FITC) - LS-C252962 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BHLHA15 Antibody (aa160-189, Azide-free, HRP) - LS-C252963 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BHLHA15 Antibody (aa160-189, PE) - LS-C252964 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BHLHA15 Antibody (aa75-141) - LS-C306540 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-BHLHA15 Antibody (aa167-189) - LS-C319837 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BHLHA15 Antibody (aa160-189) - LS-C156809 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
BHLHA15 Antibody western blot of mouse Neuro-2a cell line lysates (35 ug/lane). The BHLHA15 antibody detected the BHLHA15 protein (arrow).

Anti-BHLHA15 Antibody (Internal) IHC-plus™ - LS-B10140 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-BHLHA15 antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

MIST1 Antibody (6E8/A12/C11P1) - NBP2-22478 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 6E8/A12/C11P1
Immunohistochemistry-Paraffin: MIST1 Antibody (6E8/A12/C11P1) [NBP2-22478] - Staining of mouse pancreas tissues. The antibody gives nuclear staining in acinar cells but not in duct or islet cells.

MIST1 Antibody - NBP2-30979 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

MIST1 Antibody (1E7) - H00168620-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1E7
Sandwich ELISA: MIST1 Antibody (1E7) [H00168620-M01] - Detection limit for recombinant GST tagged BHLHA15 is 1 ng/ml as a capture antibody.

Monoclonal Anti-BHLHA15 antibody produced in mouse - SAB1402038 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1E7
<B>Immunoblotting</B><BR/>Monoclonal Anti-BHLHA15, antibody produced in mouse, clone 1E7, purified immunoglobulin: <B>Cat. No. SAB1402038</B>: Antibody concentration: 1.0 μg/mL. Specific band of ~33.37 kDa using immunogen protein lysate.
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