BHLHA15

Gene Symbol	BHLHA15
Entrez Gene	168620
Alt Symbol	BHLHB8, MIST1
Species	Human
Gene Type	protein-coding
Description	basic helix-loop-helix family, member a15
Other Description	MIST-1|basic helix-loop-helix domain containing, class B, 8|class A basic helix-loop-helix protein 15|class B basic helix-loop-helix protein 8|class II bHLH protein MIST1|muscle, intestine and stomach expression 1
Swissprots	A4D271 Q14DE4 Q7RTS1
Accessions	EAL23893 Q7RTS1 BC113394 AAI13395 BC113396 AAI13397 BK000276 DAA01056 BX648200 NM_177455 NP_803238
Function	Plays a role in controlling the transcriptional activity of MYOD1, ensuring that expanding myoblast populations remain undifferentiated. Repression may occur through muscle-specific E- box occupancy by homodimers. May also negatively regulate bHLH- mediated transcription through an N-terminal repressor domain. Serves as a key regulator of acinar cell function, stability, and identity. Also required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport. May function as a unique regulator of gene expression in several different embryonic and postnatal cell lineages. Binds to the E- box consensus sequence 5'-CANNTG-3' (By similarity). {ECO:0000250|UniProtKB:Q9QYC3}.
Subcellular Location	Nucleus {ECO:0000305}.
Tissue Specificity	Expressed in brain, liver, spleen and skeletal muscle. {ECO:0000269|PubMed:14516699}.
Top Pathways	Maturity onset diabetes of the young

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human BHLHA15 protein fragment - ab165804 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

BHLHA15 Antibody Blocking Peptide - LS-E373 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human MIST1 Protein - H00168620-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

BHLHA15-Antibody-C-term-Blocking-Peptide - BP10649b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

BHLHB8 / BHLHA15 - H00168620-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

BHLHB8 / BHLHA15 - H00168620-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

BHLHA15 Peptide - 7529P from ProSci Category Peptide Species Human

BHLHA15 fusion protein - ag18199 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

BHLHA15 fusion protein - Ag18509 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Basic Helix Loop Helix Domain Containing Protein B8 (BHLHB8) - RPL256Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Basic Helix Loop Helix Domain Containing Protein B8 (BHLHB8) - RPL256Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Class A basic helix-loop-helix protein 15(BHLHA15) - CSB-YP755911HU CSB-EP755911HU CSB-BP755911HU CSB-MP755911HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

BHLHB8 / BHLHA15 - TP315938 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

BHLHA15 Peptide - 8541P from ProSci Category Peptide Prices $70.00 Sizes 50 µg Species Human

BHLHA15 Peptide, Human - M34GP01427H from Creative Peptides Category Peptide Source Synthetic. Species Human

MIST1 Recombinant Protein Antigen - NBP2-30979PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Class A basic helix-loop-helix protein 15 (BHLHA15), Recombinant Protein - MBS1408864 from MyBioSource Category Protein Prices $935.00, $935.00, $1,160.00, $1,160.00, $1,400.00, $1,400.00, $1,855.00, $1,855.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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