RAB25

Gene Symbol	RAB25
Entrez Gene	57111
Alt Symbol	CATX-8, RAB11C
Species	Human
Gene Type	protein-coding
Description	RAB25, member RAS oncogene family
Other Description	ras-related protein Rab-25
Swissprots	Q96GB1 Q8NG24 Q9BT12 Q5VYA2 P57735
Accessions	EAW53003 P57735 AF083124 AAF98238 AF274025 AAM69362 BC004416 AAH04416 BC009831 AAH09831 BC033322 AAH33322 EU831992 ACE87433 EU832085 ACE86747 HQ448660 ADQ33138 NM_020387 NP_065120
Function	Involved in the regulation of cell survival. Promotes invasive migration of cells in which it functions to localize and maintain integrin alpha-V/beta-1 at the tips of extending pseudopodia (PubMed:17925226). Involved in the regulation of epithelial morphogenesis through the control of CLDN4 expression and localization at tight junctions (By similarity). May selectively regulate the apical recycling pathway. Together with MYO5B regulates transcytosis (By similarity). {ECO:0000250|UniProtKB:E2RQ15, ECO:0000250|UniProtKB:P46629, ECO:0000250|UniProtKB:Q9WTL2, ECO:0000269|PubMed:17925226}.
Subcellular Location	Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Cell projection, pseudopodium membrane {ECO:0000269|PubMed:17925226}. Cytoplasmic vesicle {ECO:0000269|PubMed:17925226}. Note=Colocalizes with integrin alpha-V/beta-1 in vesicles at the pseudopodial tips. {ECO:0000269|PubMed:17925226}.
Tissue Specificity	Expressed in ovarian epithelium (NOE) and breast tissue. Expressed in ovarian cancer; expression is increased relative to NOE cells. Expression in ovarian cancer is stage dependent, with stage III and stage IV showing higher levels than early stage cancers. Expressed in breast cancer; expression is increased relative to normal breast tissue. {ECO:0000269|PubMed:15502842}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Rab25 full length protein - ab131892 from Abcam Category Protein Source Wheat germ Species Human

Human Rab25 peptide - ab69566 from Abcam Category Peptide

Human Rab25 protein fragment - ab153439 from Abcam Category Protein Source Wheat germ Species Human

RAB25 Antibody Blocking Peptide - LS-E3837 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RAB25 Antibody Blocking Peptide - LS-E20955 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Rab25 Protein - H00057111-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human Rab25 Protein - H00057111-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

RAB25-Antibody-Center-Blocking-Peptide - BP16015c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

RAB25 Blocking Peptide - 33R-5083 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

RAB25 - H00057111-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

RAB25 - H00057111-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

RAB25 - H00057111-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

RAB25 - H00057111-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

RAB25 fusion protein - Ag3864 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human RAB25, GST-tagged - RAB25-2109H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Ras-related protein Rab-25(RAB25) - CSB-YP019175HU CSB-EP019175HU CSB-BP019175HU CSB-MP019175HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

RAB25 - TP303413 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Rab25 Recombinant Protein Antigen - NBP1-86612PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Source E.coli Species Human

RAB25 Peptide, Human - M34GP12835H from Creative Peptides Category Peptide Source Synthetic. Species Human

Ras-related protein Rab-25 (RAB25), Recombinant Protein - MBS717994 from MyBioSource Category Protein Prices $960.00, $960.00, $1,185.00, $1,185.00, $1,440.00, $1,440.00, $1,905.00, $1,905.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

RAB25 fusion protein - Ag27011 from Proteintech Group Category Protein Source E. coli -derived, PET28a Species Human

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