RAB25

Gene Symbol RAB25
Entrez Gene 57111
Alt Symbol CATX-8, RAB11C
Species Human
Gene Type protein-coding
Description RAB25, member RAS oncogene family
Other Description ras-related protein Rab-25
Swissprots Q96GB1 Q8NG24 Q9BT12 Q5VYA2 P57735
Accessions EAW53003 P57735 AF083124 AAF98238 AF274025 AAM69362 BC004416 AAH04416 BC009831 AAH09831 BC033322 AAH33322 EU831992 ACE87433 EU832085 ACE86747 HQ448660 ADQ33138 NM_020387 NP_065120
Function Involved in the regulation of cell survival. Promotes invasive migration of cells in which it functions to localize and maintain integrin alpha-V/beta-1 at the tips of extending pseudopodia (PubMed:17925226). Involved in the regulation of epithelial morphogenesis through the control of CLDN4 expression and localization at tight junctions (By similarity). May selectively regulate the apical recycling pathway. Together with MYO5B regulates transcytosis (By similarity). {ECO:0000250|UniProtKB:E2RQ15, ECO:0000250|UniProtKB:P46629, ECO:0000250|UniProtKB:Q9WTL2, ECO:0000269|PubMed:17925226}.
Subcellular Location Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Cell projection, pseudopodium membrane {ECO:0000269|PubMed:17925226}. Cytoplasmic vesicle {ECO:0000269|PubMed:17925226}. Note=Colocalizes with integrin alpha-V/beta-1 in vesicles at the pseudopodial tips. {ECO:0000269|PubMed:17925226}.
Tissue Specificity Expressed in ovarian epithelium (NOE) and breast tissue. Expressed in ovarian cancer; expression is increased relative to NOE cells. Expression in ovarian cancer is stage dependent, with stage III and stage IV showing higher levels than early stage cancers. Expressed in breast cancer; expression is increased relative to normal breast tissue. {ECO:0000269|PubMed:15502842}.

Rab25 (D4P6P) XP ® Rabbit mAb - 13048 from Cell Signaling Technology

Prices $109.00, $277.00
Sizes 20 µl (2 western blots), 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D4P6P
Western blot analysis of extracts from various cell lines using Rab25 (D4P6P) XP ® Rabbit mAb.

Rab25 (D3H4N) Rabbit mAb - 13081 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D3H4N
Western blot analysis of extracts from HCT-15, ZR-75-1, and MCF7 cells using Rab25 (D3H4N) Rabbit mAb.

Rab25 Antibody - 4314 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from COS-7 cells, untransfected (-) or transfected (+) with human Rab25, using Rab25 Antibody.

Rab 25 (D-3) - sc-166204 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Rab 25 (D-3): sc-166204. Western blot analysis of Rab 25 expression in non-transfected: sc-117752 (A) and human Rab 25 transfected: sc-114009 (B) 293T whole cell lysates.

Rab 25 (D-7) - sc-166144 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Rab 25 (D-7): sc-166144. Western blot analysis of Rab 25 expression in non-transfected: sc-117752 (A) and human Rab 25 transfected: sc-114009 (B) 293T whole cell lysates.

Rab 25 (3F12F3) - sc-65978 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Rab 25 (3F12F3): sc-65978. Western blot analysis of Rab 25 expression in K-562 whole cell lysate.

Rab 25 (E-7) - sc-166143 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Rab 25 (E-7): sc-166143. Western blot analysis of Rab 25 expression in non-transfected: sc-117752 (A) and human Rab 25 transfected: sc-114009 (B) 293T whole cell lysates.

Rab 25 (H-51) - sc-98697 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Rab 25 (H-51): sc-98697. Western blot analysis of Rab 25 expression in non-transfected: sc-117752 (A) and human Rab 25 transfected: sc-177814 (B) 293T whole cell lysates.

Rab 25 (S-13) - sc-74890 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Rab 25 (S-13): sc-74890. Western blot analysis of Rab 25 expression in non-transfected: sc-117752 (A) and human Rab 25 transfected: sc-114009 (B) 293T whole cell lysates.

Anti-Rab25 antibody - ab45855 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Rab25 antibody (ab45855) at 1 µg/mlLane 1 : MDA-MB-361 (Human breast adenocarcinoma cell line) Whole Cell LysateLane 2 : MCF7 (Human breast adenocarcinoma cell line) Whole Cell LysateLane 3 : T47D (Human ductal breast epithelial tumor cell line) Whole Cell LysateLysates/proteins at 10 µg per lane.SecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-Rab25 antibody - ab170040 from Abcam

Prices $378.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Rab25 antibody (ab170040) at 1/100 dilution + HEK293T cell lysate

Anti-Rab25 antibody [3F12] - ab106175 from Abcam

Prices $385.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3F12
All lanes : Anti-Rab25 antibody [3F12] (ab106175) at 1/500 dilutionLane 1 : MCF7 cell lysateLane 2 : T47D cell lysateLane 3 : GC7901 cell lysate

Anti-Rab25 antibody [3F12F3] - BSA and Azide free - ab175173 from Abcam

Prices $12,360.00
Sizes 10 ml
Host Mouse
Clonality Monoclonal
Clone 3F12F3

Anti-RAB25 Antibody (aa1-195, clone TS106) - LS-C191485 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone TS106

Anti-RAB25 Antibody (aa1-195) - LS-C184876 from LifeSpan Bioscience

Prices $605.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-RAB25 Antibody - LS-C190140 from LifeSpan Bioscience

Prices $445.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-RAB25 Antibody (aa113-141, AP) - LS-C239687 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RAB25 Antibody (aa113-141, APC) - LS-C239688 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RAB25 Antibody (aa113-141, Biotin) - LS-C239690 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RAB25 Antibody (aa113-141, FITC) - LS-C239689 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RAB25 Antibody (aa113-141, PE) - LS-C239693 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RAB25 Antibody (aa112-141) - LS-C324471 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RAB25 Antibody (aa113-141, Azide-free, HRP) - LS-C248603 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RAB25 Antibody (aa107-156) - LS-C135443 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
RAB25 antibody LS-C135443 Western blot of Transfected 293T cell lysate.

Anti-RAB25 Antibody (aa113-141) - LS-C162373 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
RAB25 Antibody western blot of mouse stomach,bladder tissue lysates (35 ug/lane). The RAB25 antibody detected the RAB25 protein (arrow).
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