MCHR1

Gene Symbol MCHR1
Entrez Gene 2847
Alt Symbol GPR24, MCH-1R, MCH1R, SLC-1, SLC1
Species Human
Gene Type protein-coding
Description melanin-concentrating hormone receptor 1
Other Description G protein-coupled receptor 24|MCH receptor 1|somatostatin receptor-like protein
Swissprots Q9BV08 Q5R3J1 Q96S47 B2RBX6 Q99705
Accessions AAC14587 EAW60387 EAW60388 Q99705 AB063174 BAB60890 AF490537 AAO14670 AI934819 AK308739 AK314857 BAG37373 AY562945 AAS72373 AY745811 AAV98052 AY747629 AAV98053 BC001736 AAH01736 BC021146 AAH21146 BT006725 AAP35371 CR456497 CAG30383 CU013094 CAK54525 CU013382 CAK54824 DQ893603 ABM84529 DQ895065 ABM85991 NM_005297 NP_005288
Function Receptor for melanin-concentrating hormone, coupled to both G proteins that inhibit adenylyl cyclase and G proteins that activate phosphoinositide hydrolysis. {ECO:0000269|PubMed:10421367}.
Subcellular Location Cell membrane; Multi-pass membrane protein.
Tissue Specificity Highest level in brain, particularly in the frontal cortex and hypothalamus, lower levels in the liver and heart.
Top Pathways Neuroactive ligand-receptor interaction

MCH-1R (C-17) - sc-5534 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
MCH-1R (C-17): sc-5534. Western blot analysis of MCH-1R expression in rat hypothalmus (A) and rat cerebellum (B) tissue extracts.

MCH-1R (C-20) - sc-14513 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
MCH-1R (C-20): sc-14513. Immunoperoxidase staining of formalin fixed, paraffin-embedded human skin tissue showing cytoplasmic staining of keratinocytes, Langerhans cells and melanocytes.

MCH-1R (H-190) - sc-25667 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

MCH-1R (N-15) - sc-14510 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

MCH-1R (W-17) - sc-14511 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

MCH-1R (52-W7) - sc-100327 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
MCH-1R (52-W7): sc-100327. Western blot analysis of MCH-1R expression in HL-60 whole cell lysate.

Anti-MCHR antibody - ab97509 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-MCHR antibody (ab97509) at 1/1000 dilution + IMR32 whole cell lysate at 30 µg

Anti-MCHR antibody - ab115474 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ab115474 at 10-18ug/ml staining MCHR in Formalin-fixed, Paraffin-embedded Human brain (substantia nigra) tissue by Immunohistochemistry, followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen

Anti-MCHR antibody - ab107539 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-MCHR antibody (ab107539) at 1/100 dilution + K562 cell line lysates at 35 µg

Anti-MCHR antibody - ab55137 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-MCHR antibody - ab128288 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-MCHR antibody (ab128288) at 1 µg/ml + 293T cell lysate at 10 µgdeveloped using the ECL technique

Anti-MCHR antibody - N-terminal - ab140881 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry analysis of Formalin fixed and Paraffin Embedded Human adrenal tissue labelling MCHR with ab140881 at 15 µg/ml.

Anti-MCHR antibody - N-terminal - ab188945 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human brain tissue labeling MCHR with ab188945 at 44µg/ml.

Anti-MCHR1 Antibody (C-Terminus) - LS-C8964 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-MCHR1 Antibody (C-Terminus) - LS-C8965 from LifeSpan Bioscience

Prices $385.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-MCHR1 Antibody (aa14-114) - LS-C125929 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-MCHR1 Antibody (aa1-422) - LS-C130706 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MCHR1 Antibody (aa399-426, AP) - LS-C262839 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MCHR1 Antibody (aa399-426, Biotin) - LS-C262841 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MCHR1 Antibody (aa399-426, APC) - LS-C262840 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MCHR1 Antibody (aa399-426, Azide-free, HRP) - LS-C262843 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MCHR1 Antibody (aa399-426, FITC) - LS-C262842 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MCHR1 Antibody (aa56-105) - LS-C151532 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
MCHR1 antibody Western Blot of 293T.

Anti-MCHR1 Antibody (aa399-426, PE) - LS-C262844 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MCHR1 Antibody (aa358-422) - LS-C185953 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Sample (30 ug of whole cell lysate). A: IMR32 10% SDS PAGE. SLC1 / MCHR1 antibody diluted at 1:1000.
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