| Gene Symbol |
MCHR1
|
| Entrez Gene |
2847
|
| Alt Symbol |
GPR24, MCH-1R, MCH1R, SLC-1, SLC1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
melanin-concentrating hormone receptor 1
|
| Other Description |
G protein-coupled receptor 24|MCH receptor 1|somatostatin receptor-like protein
|
| Swissprots |
Q9BV08 Q5R3J1 Q96S47 B2RBX6 Q99705
|
| Accessions |
AAC14587 EAW60387 EAW60388 Q99705 AB063174 BAB60890 AF490537 AAO14670 AI934819 AK308739 AK314857 BAG37373 AY562945 AAS72373 AY745811 AAV98052 AY747629 AAV98053 BC001736 AAH01736 BC021146 AAH21146 BT006725 AAP35371 CR456497 CAG30383 CU013094 CAK54525 CU013382 CAK54824 DQ893603 ABM84529 DQ895065 ABM85991 NM_005297 NP_005288
|
| Function |
Receptor for melanin-concentrating hormone, coupled to both G proteins that inhibit adenylyl cyclase and G proteins that activate phosphoinositide hydrolysis. {ECO:0000269|PubMed:10421367}.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Highest level in brain, particularly in the frontal cortex and hypothalamus, lower levels in the liver and heart.
|
| Top Pathways |
Neuroactive ligand-receptor interaction
|
![Western Blot: MCHR Overexpression Lysate (Adult Normal) [NBL1-12947] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for MCHR.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/4035_MCHR%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-12947-img0002.jpg)