Gene Symbol | UBA52 |
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Entrez Gene | 7311 |
Alt Symbol | CEP52, HUBCEP52, L40, RPL40 |
Species | Human |
Gene Type | protein-coding |
Description | ubiquitin A-52 residue ribosomal protein fusion product 1 |
Other Description | 60S ribosomal protein L40|ubiquitin carboxyl extension protein 52|ubiquitin-52 amino acid fusion protein|ubiquitin-60S ribosomal protein L40|ubiquitin-CEP52 |
Swissprots | P14793 P62987 |
Accessions | AAC25582 ABE96835 CAA40312 EAW84715 EAW84716 EAW84717 EAW84718 P62987 AF348700 AAK31162 AF545864 AAP97731 AK057790 AK314717 BAG37261 BC101830 AAI01831 BC101832 AAI01833 BC143668 AAI43669 BQ428515 BQ428688 BU677484 CB124676 D28425 BAA05791 X56998 CAA40313 X56999 CAA40314 Y00361 CAA68439 XM_005260051 XP_005260108 XM_005260052 XP_005260109 XM_005260053 XP_005260110 XM_005260054 XP_005260111 XM_006722871 XP_006722934 NM_001033930 NP_001029102 NM_003333 NP_003324 |
Function | Ubiquitin: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; Lys-11-linked is involved in ERAD (endoplasmic reticulum-associated degradation) and in cell-cycle regulation; Lys-29-linked is involved in lysosomal degradation; Lys-33-linked is involved in kinase modification; Lys-48-linked is involved in protein degradation via the proteasome; Lys-63-linked is involved in endocytosis, DNA-damage responses as well as in signaling processes leading to activation of the transcription fac |
Subcellular Location | Ubiquitin: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. |
Top Pathways | Ribosome |
Human UBA52 protein fragment - ab159768 from Abcam
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UBA52 Antibody Blocking Peptide - LS-E90 from LifeSpan Bioscience
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Recombinant Human UBA52 Protein - H00007311-Q01 from Novus Biologicals
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UBA52-Antibody-C-Term-Blocking-peptide - BP10176b from Abgent, a WuXi AppTec company
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Ubiquitin protein - 30R-2726 from Fitzgerald
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UBA52 - H00007311-Q01-10 from Acris Antibodies
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UBA52 - H00007311-Q01-25 from Acris Antibodies
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UBA52 fusion protein - Ag12669 from Proteintech Group
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UBA52 fusion protein - ag12687 from Proteintech Group
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Recombinant Human UBA52, GST-tagged - UBA52-3517H from Creative Biomart
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Recombinant Ubiquitin A 52 Residue Ribosomal Protein Fusion Product 1 (UBA52) - RPE592Hu01 from Uscn Life Science Inc.
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Ub Blocking Peptide - CBP2201 from Cohesion Biosciences
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Recombinant Ubiquitin A 52 Residue Ribosomal Protein Fusion Product 1 (UBA52) - RPE592Hu01 from Cloud-clone
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Recombinant Human Ubiquitin-60S ribosomal protein L40(UBA52) - CSB-YP025416HU CSB-EP025416HU CSB-BP025416HU CSB-MP025416HU from Cusabio
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UBA52 (transcript variant 2) - TP311036 from Acris Antibodies
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UBA52 Peptide, Human - M34GP16933H from Creative Peptides
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Ub Blocking Peptide - CBP7412 from Cohesion Biosciences
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UBA52 Recombinant Protein (OPCD07784) - OPCD07784 from Aviva Systems Biology
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UBA52 Recombinant Protein Antigen - NBP2-55293PEP from Novus Biologicals
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Recombinant Human UBA52 protein, His & T7-tagged - UBA52-1246H from Creative Biomart
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