Gene Symbol | UBA52 |
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Entrez Gene | 7311 |
Alt Symbol | CEP52, HUBCEP52, L40, RPL40 |
Species | Human |
Gene Type | protein-coding |
Description | ubiquitin A-52 residue ribosomal protein fusion product 1 |
Other Description | 60S ribosomal protein L40|ubiquitin carboxyl extension protein 52|ubiquitin-52 amino acid fusion protein|ubiquitin-60S ribosomal protein L40|ubiquitin-CEP52 |
Swissprots | P14793 P62987 |
Accessions | AAC25582 ABE96835 CAA40312 EAW84715 EAW84716 EAW84717 EAW84718 P62987 AF348700 AAK31162 AF545864 AAP97731 AK057790 AK314717 BAG37261 BC101830 AAI01831 BC101832 AAI01833 BC143668 AAI43669 BQ428515 BQ428688 BU677484 CB124676 D28425 BAA05791 X56998 CAA40313 X56999 CAA40314 Y00361 CAA68439 XM_005260051 XP_005260108 XM_005260052 XP_005260109 XM_005260053 XP_005260110 XM_005260054 XP_005260111 XM_006722871 XP_006722934 NM_001033930 NP_001029102 NM_003333 NP_003324 |
Function | Ubiquitin: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; Lys-11-linked is involved in ERAD (endoplasmic reticulum-associated degradation) and in cell-cycle regulation; Lys-29-linked is involved in lysosomal degradation; Lys-33-linked is involved in kinase modification; Lys-48-linked is involved in protein degradation via the proteasome; Lys-63-linked is involved in endocytosis, DNA-damage responses as well as in signaling processes leading to activation of the transcription fac |
Subcellular Location | Ubiquitin: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. |
Top Pathways | Ribosome |
UBA52 (C-14) - sc-324975 from Santa Cruz Biotechnology
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UBA52 (Y-13) - sc-324974 from Santa Cruz Biotechnology
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Anti-UBA52 antibody - ab104455 from Abcam
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Anti-UBA52 antibody - ab104651 from Abcam
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Anti-UBA52 antibody - ab196778 from Abcam
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Anti-UBA52 antibody [EPR4546] - ab109227 from Abcam
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Anti-UBA52 antibody [EPR4547] - ab109230 from Abcam
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Anti-UBA52 Antibody (aa100-128, AP) - LS-C218229 from LifeSpan Bioscience
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Anti-UBA52 Antibody (aa100-128, APC) - LS-C218230 from LifeSpan Bioscience
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Anti-UBA52 Antibody (aa100-128, Biotin) - LS-C218232 from LifeSpan Bioscience
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Anti-UBA52 Antibody (aa100-128, FITC) - LS-C218233 from LifeSpan Bioscience
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Anti-UBA52 Antibody (aa100-128, Azide-free, HRP) - LS-C218234 from LifeSpan Bioscience
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Anti-UBA52 Antibody (aa100-128, PE) - LS-C218235 from LifeSpan Bioscience
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Anti-UBA52 Antibody (aa107-136) - LS-C326121 from LifeSpan Bioscience
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Anti-UBA52 Antibody (Internal, clone EPR4547) - LS-C137849 from LifeSpan Bioscience
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Anti-UBA52 Antibody (aa77-128, clone 5H7) - LS-C339377 from LifeSpan Bioscience
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Anti-UBA52 Antibody (aa77-128, clone 6H4) - LS-C339376 from LifeSpan Bioscience
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Anti-UBA52 Antibody (aa77-128, clone 4E1) - LS-C339361 from LifeSpan Bioscience
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Anti-UBA52 Antibody (aa77-128, clone 2F1) - LS-C339375 from LifeSpan Bioscience
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Anti-UBA52 Antibody (aa77-128, clone 4A3) - LS-C339378 from LifeSpan Bioscience
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Anti-UBA52 Antibody (aa77-128, clone 5E3) - LS-C339397 from LifeSpan Bioscience
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Anti-UBA52 Antibody (aa77-128, clone 8H2) - LS-C339399 from LifeSpan Bioscience
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Anti-UBA52 Antibody (aa77-128, clone 3C4) - LS-C339398 from LifeSpan Bioscience
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Anti-UBA52 Antibody (aa77-128, clone 7A8) - LS-C339400 from LifeSpan Bioscience
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Anti-UBA52 Antibody (aa77-128, clone 7G6) - LS-C339440 from LifeSpan Bioscience
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