AOC3

Gene Symbol	AOC3
Entrez Gene	8639
Alt Symbol	HPAO, SSAO, VAP-1, VAP1
Species	Human
Gene Type	protein-coding
Description	amine oxidase, copper containing 3
Other Description	amine oxidase, copper containing 3 (vascular adhesion protein 1)|copper amine oxidase|membrane primary amine oxidase|placenta copper monamine oxidase|semicarbazide-sensitive amine oxidase
Swissprots	Q16853 Q45F94 L0L8N9 K7ESB3 B2RCI5
Accessions	AAZ38716 BAB18866 EAW60897 Q16853 AF054985 AAC09346 AF067406 AAC25170 AK025727 AK315129 BAG37582 BC036368 BC050549 AAH50549 DA592022 DB250074 JX020506 AGB67480 U39447 AAC50919 XM_011525419 XP_011523721 XM_011525420 XP_011523722 XR_934584 NM_001277731 NP_001264660 NM_001277732 NP_001264661 NM_003734 NP_003725 NR_102422
Function	Cell adhesion protein that participates in lymphocyte extravasation and recirculation by mediating the binding of lymphocytes to peripheral lymph node vascular endothelial cells in an L-selectin-independent fashion. Has semicarbazide-sensitive (SSAO) monoamine oxidase activity. May play a role in adipogenesis. {ECO:0000269|PubMed:17400359, ECO:0000269|PubMed:19588076, ECO:0000269|PubMed:23349812, ECO:0000269|PubMed:9653080}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:9653080}; Single-pass type II membrane protein {ECO:0000269|PubMed:9653080}.
Tissue Specificity	Strongly expressed on the high endothelial venules of peripheral lymph nodes and on hepatic endothelia. Also highly expressed in appendix, lung and small intestine. Expressed also in adipose tissue, in bone marrow, colon, heart, kidney, ovary, pancreas, placenta, prostate, skeletal muscle, spleen and testis. Isoform 2 seems to be the predominant transcript in fetal kidneys, fetal cartilage and fetal tonsils. The highest relative expression of isoform 2 occurs in skeletal muscle, heart, pancreas, kidney, and lung. {ECO:0000269|PubMed:17400359, ECO:0000269|PubMed:23349812, ECO:0000269|PubMed:9653080}.
Top Pathways	Glycine, serine and threonine metabolism, Phenylalanine metabolism, Tyrosine metabolism, beta-Alanine metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

AOC3 - MBS1268953 from MyBioSource Species Human Accession BC050549

Human AOC3 cDNA clone(NM_003734.2) - CDFH000883 from Creative Biomart Species Human Accession NM_003734.2

Human AOC3 ORF Clone(NM_003734.2) - CDCL153981 from Creative Biomart Species Human Accession NM_003734.2

Human AOC3 ORF Clone(NM_003734.2) - CDCR286360 from Creative Biomart Species Human Accession NM_003734.2

Human AOC3 ORF Clone(NM_003734.2) - CDCR286361 from Creative Biomart Species Human Accession NM_003734.2

Human AOC3 ORF Clone(NM_003734.2) - CDCR286362 from Creative Biomart Species Human Accession NM_003734.2

Human VAP1/AOC3 Gene ORF cDNA clone in cloning vector - HG12009-G from Sino Biological Species Human

Human VAP1/AOC3 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG12009-CM from Sino Biological Species Human

Human VAP1/AOC3 Gene ORF cDNA clone expression plasmid, C-His tag - HG12009-CH from Sino Biological Species Human

Human VAP1/AOC3 Gene ORF cDNA clone expression plasmid - HG12009-UT from Sino Biological Species Human

Human VAP1/AOC3 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG12009-ACG from Sino Biological Species Human

Human VAP1/AOC3 Gene ORF cDNA clone expression plasmid, C-HA tag - HG12009-CY from Sino Biological Species Human

Human VAP1/AOC3 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG12009-NF from Sino Biological Species Human

Human VAP1/AOC3 Gene ORF cDNA clone expression plasmid, N-HA tag - HG12009-NY from Sino Biological Species Human

Human VAP1/AOC3 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG12009-ACR from Sino Biological Species Human

Human VAP1/AOC3 Gene ORF cDNA clone expression plasmid, N-His tag - HG12009-NH from Sino Biological Species Human

Human VAP1/AOC3 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG12009-CF from Sino Biological Species Human

Human VAP1/AOC3 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG12009-NM from Sino Biological Species Human

Human AOC3 ORF clone (NM_003734.2) - CDCR028364 from Creative biogene Species Human

Human AOC3 ORF Clone (BC050549) - CDCS411435 from Creative biogene Species Human Accession Q16853

Human AOC3 ORF clone (NM_003734) - CDCB160310 from Creative biogene Species Human

Human AOC3 cDNA Clone(NM_003734.2) - CDFH000883 from Creative biogene Species Human

Human AOC3 gene - orb92494 from Biorbyt Prices $264.00 Sizes 10 μg Species Human

Mouse VAP-1/AOC3 (NP_033805) VersaClone cDNA - RDC2050 from R&D Systems Prices $499.00 Sizes 10 µg Species Mouse

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