Gene Symbol | E2f6 |
---|---|
Entrez Gene | 50496 |
Alt Symbol | AI462434, E2F6b, EMA |
Species | Mouse |
Gene Type | protein-coding |
Description | E2F transcription factor 6 |
Other Description | E2F-6|E2F-binding site-modulating activity protein|transcription factor E2F6|transcriptional repressor E2F6 |
Swissprots | Q8K456 O54917 |
Accessions | AAL38216 AAL38217 AAM45941 AAM45942 EDK98479 O54917 AB221552 AF032131 AAC53521 AI851823 AK035116 BAC28950 AK075684 AK146792 BAE27435 AK149061 BAE28727 AK177128 AK183289 AK187122 BC019166 AAH19166 BC037656 AAH37656 BC057929 AAH57929 BY739130 CJ075693 XM_006515147 XP_006515210 XM_006515148 XP_006515211 XM_006515149 XP_006515212 XM_011243882 XP_011242184 NM_033270 NP_150373 NR_027677 |
Function | Inhibitor of E2F-dependent transcription. Binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3'. Has a preference for the 5'-TTTCCCGC-3' E2F recognition site. E2F6 lacks the transcriptional activation and pocket protein binding domains. Appears to regulate a subset of E2F-dependent genes whose products are required for entry into the cell cycle but not for normal cell cycle progression. May silence expression via the recruitment of a chromatin remodeling complex containing histone H3-K9 methyltransferase activity. Overexpression delays the exit of cells from the S-phase (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000305}. |
E2F-6 (M-40) - sc-22824 from Santa Cruz Biotechnology
|
||||||||||
E2F-6 (E-5) - sc-390022 from Santa Cruz Biotechnology
|
||||||||||
Anti-E2F6 Antibody - LS-C65139 from LifeSpan Bioscience
|
||||||||||
Anti-E2F6 Antibody - LS-C124945 from LifeSpan Bioscience
|
||||||||||
Anti-E2F6 Antibody (clone 2B6-G9) - LS-C139494 from LifeSpan Bioscience
|
||||||||||
Anti-E2F6 Antibody (aa43-92) - LS-C30546 from LifeSpan Bioscience
|
||||||||||
Anti-E2F6 Antibody - LS-C310208 from LifeSpan Bioscience
|
||||||||||
Anti-E2F6 Antibody - LS-C310209 from LifeSpan Bioscience
|
||||||||||
Anti-E2F6 Antibody (aa43-92) - LS-C29812 from LifeSpan Bioscience
|
||||||||||
Anti-E2F6 Antibody (aa162-177) - LS-C312953 from LifeSpan Bioscience
|
||||||||||
Anti-E2F6 Antibody (clone E2F6B9E2) - LS-C184330 from LifeSpan Bioscience
|
||||||||||
Anti-E2F6 Antibody (aa101-150) - LS-C170355 from LifeSpan Bioscience
|
||||||||||
Anti-E2F6 Antibody (aa269-281) - LS-C108901 from LifeSpan Bioscience
|
||||||||||
Anti-E2F6 Antibody (clone E2F6B9E2) - LS-C342384 from LifeSpan Bioscience
|
||||||||||
Anti-E2F6 Antibody - LS-C334526 from LifeSpan Bioscience
|
||||||||||
Anti-E2F6 Antibody (Glu170) - LS-C175996 from LifeSpan Bioscience
|
||||||||||
Anti-E2F6 Antibody (aa141-190) IHC-plus⢠- LS-B8383 from LifeSpan Bioscience
|
||||||||||
E2F6 antibody - 70R-31169 from Fitzgerald
|
||||||||||
Anti-Electron Transfer Flavoprotein Alpha Poly - 20-5019 from ARP American Research Products
|
||||||||||
Anti-Mucin 1 (MUC1) - 20-2667 from ARP American Research Products
|
||||||||||
E2F6, Polyclonal Antibody - MBS247518 from MyBioSource
|
||||||||||
E2F6 (Internal) antibody - pab75663 from Covalab
|
||||||||||
Polyclonal Antibody to Electron Transfer Flavoprotein Alpha Polypeptide (ETFa) - PAE527Mu01 from Cloud-clone
|
||||||||||
Anti-E2F6 Antibody (Internal) - LS-C352133 from LifeSpan Bioscience
|
||||||||||
E2f6 Antibody (OALA06894) - OALA06894 from Aviva Systems Biology
|