Gene Symbol | PI4KA |
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Entrez Gene | 5297 |
Alt Symbol | PI4K-ALPHA, PIK4CA, pi4K230 |
Species | Human |
Gene Type | protein-coding |
Description | phosphatidylinositol 4-kinase, catalytic, alpha |
Other Description | PI4-kinase alpha|phosphatidylinositol 4-kinase 230|phosphatidylinositol 4-kinase alpha|phosphatidylinositol 4-kinase, type III, alpha|ptdIns-4-kinase alpha |
Swissprots | P42356 Q7Z625 Q9UPG2 |
Accessions | P42356 AB210002 BAE06084 AF012872 AAD13352 AK094594 AK095811 BAG53136 AK124692 AK131431 AK302424 BAG63727 AK314781 BAG37317 AL048955 BC018120 AAH18120 BC046202 BC053654 AAH53654 BC172398 AAI72398 BU685224 DA959365 L36151 AAA56839 XM_005261634 XP_005261691 XM_005261635 XP_005261692 XM_011530226 XP_011528528 XM_011530227 XP_011528529 XM_011530228 XP_011528530 XR_937868 NM_058004 NP_477352 NM_002650 |
Function | Acts on phosphatidylinositol (PtdIns) in the first committed step in the production of the second messenger inositol- 1,4,5,-trisphosphate. |
Subcellular Location | Cytoplasm {ECO:0000250}. Membrane {ECO:0000250}. Note=Associates with the membranes of Golgi vesicles and vacuoles. {ECO:0000250}. |
Tissue Specificity | Expressed ubiquitously. Highest levels in placenta and brain. Little or no expression in lung, liver, pancreas, testis or leukocytes. {ECO:0000269|PubMed:10101268, ECO:0000269|PubMed:7961848}. |
Top Pathways | Inositol phosphate metabolism, Phosphatidylinositol signaling system |
PI4 Kinase Antibody - 4902 from Cell Signaling Technology
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PI 4-kinase α (H-142) - sc-10799 from Santa Cruz Biotechnology
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PI 4-kinase α (N-19) - sc-1328 from Santa Cruz Biotechnology
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PI 4-kinase α (C-20) - sc-1327 from Santa Cruz Biotechnology
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Anti-PI4KA Antibody - LS-C38244 from LifeSpan Bioscience
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Anti-PI4KA antibody produced in rabbit - SAB2700958 from Sigma-Aldrich
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Anti-PI4KCA (N-term) antibody produced in rabbit - SAB1300025 from Sigma-Aldrich
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Anti-PI4KCA (C-term) antibody produced in rabbit - SAB1300440 from Sigma-Aldrich
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PI4KA antibody - 70R-19274 from Fitzgerald
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Phosphatidylinositol 4-Kinase, Catalytic, Alpha Antibody - abx114438 from Abbexa
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PI4KA antibody - 12411-1-AP from Acris Antibodies
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PI4KA antibody - 12411-1-AP from Proteintech Group
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PI4KA antibody - 66027-1-Ig from Proteintech Group
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phosphatidylinositol 4-kinase, catalytic, alpha , Polyclonal Antibody - MBS710596 from MyBioSource
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Anti-PI4KA (aa 1-331) polyclonal antibody - DPABH-01765 from Creative Diagnostics
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Anti-PI4KA monoclonal antibody - DCABH-12912 from Creative Diagnostics
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PI4KA Polyclonal Antibody - PA5-28570 from Thermo Fisher Scientific
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PI 4-Kinase, Polyclonal Antibody - MBS611815 from MyBioSource
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PI4 kinase alpha - MBS276181 from MyBioSource
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PI4KA Antibody - CSB-PA017955GA01HU from Cusabio
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PI4KA, Polyclonal Antibody - MBS5303078 from MyBioSource
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Polyclonal Antibody to Phosphatidylinositol-4-Kinase Catalytic Alpha (PI4Ka) - PAG843Hu01 from Uscn Life Science Inc.
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Polyclonal Antibody to Phosphatidylinositol-4-Kinase Catalytic Alpha (PI4Ka) - PAG843Hu01 from Cloud-clone
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Phosphatidylinositol-4-Kinase Catalytic Alpha, Polyclonal Antibody - MBS2026525 from MyBioSource
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PI4KA Monoclonal Antibody - EPM12830 from Elabscience
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