Gene Symbol | PI4KA |
---|---|
Entrez Gene | 5297 |
Alt Symbol | PI4K-ALPHA, PIK4CA, pi4K230 |
Species | Human |
Gene Type | protein-coding |
Description | phosphatidylinositol 4-kinase, catalytic, alpha |
Other Description | PI4-kinase alpha|phosphatidylinositol 4-kinase 230|phosphatidylinositol 4-kinase alpha|phosphatidylinositol 4-kinase, type III, alpha|ptdIns-4-kinase alpha |
Swissprots | P42356 Q7Z625 Q9UPG2 |
Accessions | P42356 AB210002 BAE06084 AF012872 AAD13352 AK094594 AK095811 BAG53136 AK124692 AK131431 AK302424 BAG63727 AK314781 BAG37317 AL048955 BC018120 AAH18120 BC046202 BC053654 AAH53654 BC172398 AAI72398 BU685224 DA959365 L36151 AAA56839 XM_005261634 XP_005261691 XM_005261635 XP_005261692 XM_011530226 XP_011528528 XM_011530227 XP_011528529 XM_011530228 XP_011528530 XR_937868 NM_058004 NP_477352 NM_002650 |
Function | Acts on phosphatidylinositol (PtdIns) in the first committed step in the production of the second messenger inositol- 1,4,5,-trisphosphate. |
Subcellular Location | Cytoplasm {ECO:0000250}. Membrane {ECO:0000250}. Note=Associates with the membranes of Golgi vesicles and vacuoles. {ECO:0000250}. |
Tissue Specificity | Expressed ubiquitously. Highest levels in placenta and brain. Little or no expression in lung, liver, pancreas, testis or leukocytes. {ECO:0000269|PubMed:10101268, ECO:0000269|PubMed:7961848}. |
Top Pathways | Inositol phosphate metabolism, Phosphatidylinositol signaling system |
Human Phosphatidylinositol 4 kinase III alpha full length protein - ab159132 from Abcam
|
||||||||||
Human Phosphatidylinositol 4 kinase III alpha protein fragment - ab114905 from Abcam
|
||||||||||
Recombinant Human PIK4CA Protein - H00005297-P01 from Novus Biologicals
|
||||||||||
PIK4CA Partial Recombinant Protein - H00005297-Q01 from Novus Biologicals
|
||||||||||
Recombinant Human PIK4CA Protein - H00005297-A01 from Novus Biologicals
|
||||||||||
PIK4CA Peptide - P3012 from Novus Biologicals
|
||||||||||
PI4KCA-Antibody-N-term-Blocking-Peptide - BP8029a from Abgent, a WuXi AppTec company
|
||||||||||
PI4KA - H00005297-P01 from Acris Antibodies
|
||||||||||
PI4KA - H00005297-Q01-10 from Acris Antibodies
|
||||||||||
PI4KA - H00005297-Q01-25 from Acris Antibodies
|
||||||||||
PI4KA fusion protein - Ag17168 from Proteintech Group
|
||||||||||
PI4KA fusion protein - Ag3062 from Proteintech Group
|
||||||||||
Recombinant Human PI4KA - PI4KA-30331TH from Creative Biomart
|
||||||||||
Recombinant Human PI4KA, GST-tagged - PI4KA-117H from Creative Biomart
|
||||||||||
Recombinant Human PI4KA, His-tagged - PI4KA-1700H from Creative Biomart
|
||||||||||
Recombinant Human Phosphatidylinositol 4-kinase alpha(PI4KA) ,partial - CSB-YP017955HU CSB-EP017955HU CSB-BP017955HU CSB-MP017955HU from Cusabio
|
||||||||||
Recombinant Phosphatidylinositol-4-Kinase Catalytic Alpha (PI4Ka) - RPG843Hu01 from Cloud-clone
|
||||||||||
Recombinant Phosphatidylinositol-4-Kinase Catalytic Alpha (PI4Ka) - RPG843Hu01 from Uscn Life Science Inc.
|
||||||||||
Phosphatidylinositol 4-kinase alpha (PI4KA), partial, Recombinant Protein - MBS957756 from MyBioSource
|
||||||||||
PI4KA, Recombinant Protein - MBS515434 from MyBioSource
|
||||||||||
PI4KIIIα Protein, 250 µg - 14-908M from EMD Millipore
|
||||||||||
PI4KIIIα Protein - 14-908 from EMD Millipore
|
||||||||||
PI4KCA-Antibody-C-term-Blocking-Peptide - BP8029b from Abgent, a WuXi AppTec company
|
||||||||||
PI4KA Peptide, Human - M34GP11739H from Creative Peptides
|
||||||||||
PI4KA Recombinant Protein (OPCD06159) - OPCD06159 from Aviva Systems Biology
|