PTPRU

Gene Symbol PTPRU
Entrez Gene 10076
Alt Symbol FMI, PCP-2, PTP, PTP-J, PTP-PI, PTP-RO, PTPPSI, PTPRO, PTPU2, R-PTP-PSI, R-PTP-U, hPTP-J
Species Human
Gene Type protein-coding
Description protein tyrosine phosphatase, receptor type, U
Other Description PTP pi|Receptor protein tyrosine phosphatase hPTP-J|pancreatic carcinoma phosphatase 2|pi R-PTP-Psi|protein-tyrosine phosphatase J|protein-tyrosine phosphatase pi|protein-tyrosine phosphatase receptor omicron|receptor-type protein-tyrosine phosphatase psi|receptor-type tyrosine-protein phosphatase U
Swissprots Q5SYU4 Q92850 Q5SYU5 Q92729 Q92735 A6H8L1 O00197 P78399 Q59HA4
Accessions AAB07074 CCQ43332 EAX07650 EAX07651 EAX07652 Q92729 AB208855 BAD92092 AK094849 BAG52941 BC033131 BC146655 AAI46656 BM799833 BU687539 CN410555 U71075 AAC51938 U73727 AAB51343 X95712 CAA65016 X97198 CAA65832 XM_006710269 XP_006710332 XM_006710270 XP_006710333 XM_006710272 XP_006710335 XM_006710273 XP_006710336 XM_011540458 XP_011538760 NM_001195001 NP_001181930 NM_005704 NP_005695 NM_133177 NP_573438 NM_133178 NP_573439
Function Tyrosine-protein phosphatase which dephosphorylates CTNNB1. Regulates CTNNB1 function both in cell adhesion and signaling. May function in cell proliferation and migration and play a role in the maintenance of epithelial integrity. May play a role in megakaryocytopoiesis. {ECO:0000269|PubMed:10397721, ECO:0000269|PubMed:12501215, ECO:0000269|PubMed:16574648}.
Subcellular Location Cell junction {ECO:0000269|PubMed:8700514}. Cell membrane {ECO:0000269|PubMed:8700514}; Single-pass type I membrane protein {ECO:0000269|PubMed:8700514}.
Tissue Specificity High levels in brain, pancreas, and skeletal muscle; less in colon, kidney, liver, stomach, and uterus; not expressed in placenta and spleen. Also detected in heart, prostate, lung, thymus, testis and ovary. Ubiquitously expressed in brain. Expressed by hematopoietic stem cells. {ECO:0000269|PubMed:8700514, ECO:0000269|PubMed:8870675, ECO:0000269|PubMed:9070223, ECO:0000269|PubMed:9434160}.

Human PTP lambda peptide - ab13230 from Abcam

Category Peptide
All lanes : Anti-PTP lambda antibody ( ab13223 ) at 1/500 dilution Lane 1 : Human brain lysate Lane 2 : Human kidney lysate Lane 3 : Human pancreas lysate Lane 4 : Human heart lysate Lane 5 : Human brain lysate with Human PTP lambda peptide (ab13230) at 1 µg/ml Lane 6 : Human kidney lysate with Human PTP lambda peptide (ab13230) at 1 µg/ml Lane 7 : Human pancreas lysate with Human PTP lambda peptide (ab13230) at 1 µg/ml Lane 8 : Human heart lysate with Human PTP lambda peptide (ab13230) at 1 µg/ml Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG H&L (HRP) ( ab6721 ) at 1/5000 dilution Performed under reducing conditions. Exposure time : 5 minutes A weak band of predicted size (~160kDa) is observed in human kidney lysate which is quenched by the blocking peptide (ab13230).

PTPRU fusion protein - ag15542 from Proteintech Group

Category Protein
Source E. coli-derived, PET28a
Species Human

Recombinant Human Receptor-type tyrosine-protein phosphatase U(PTPRU) - CSB-YP856420HU CSB-EP856420HU CSB-BP856420HU CSB-MP856420HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

PTPRU Protein - abx163631 from Abbexa

Category Protein
Species Mouse, Rat

Recombinant Protein Tyrosine Phosphatase Receptor Type U (PTPRU) - RPD605Hu01 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Human

PTP pi/PTPRU Recombinant Protein Antigen - NBP1-81873PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

PTPRU-PTP-U-Antibody-N-term-Blocking-peptide - BP8418a from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

PTPRU Peptide, Human - M34GP12731H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

PTPRU Recombinant Protein (OPCD00405) - OPCD00405 from Aviva Systems Biology

Category Protein
Source E.coli
Species Human

Protein Tyrosine Phosphatase Receptor Type U, Recombinant Protein - MBS2034179 from MyBioSource

Category Protein
Prices $160.00, $315.00, $490.00
Sizes 10 µg, 50 µg, 100 µg
Source Prokaryotic Expression
Species Human

Receptor-type tyrosine-protein phosphatase U (PTPRU), Recombinant Protein - MBS1464088 from MyBioSource

Category Protein
Prices $1,540.00, $1,540.00, $1,770.00, $1,770.00, $2,650.00, $2,650.00, $3,090.00, $3,090.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human
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