PTPRU

Gene Symbol PTPRU
Entrez Gene 10076
Alt Symbol FMI, PCP-2, PTP, PTP-J, PTP-PI, PTP-RO, PTPPSI, PTPRO, PTPU2, R-PTP-PSI, R-PTP-U, hPTP-J
Species Human
Gene Type protein-coding
Description protein tyrosine phosphatase, receptor type, U
Other Description PTP pi|Receptor protein tyrosine phosphatase hPTP-J|pancreatic carcinoma phosphatase 2|pi R-PTP-Psi|protein-tyrosine phosphatase J|protein-tyrosine phosphatase pi|protein-tyrosine phosphatase receptor omicron|receptor-type protein-tyrosine phosphatase psi|receptor-type tyrosine-protein phosphatase U
Swissprots Q5SYU4 Q92850 Q5SYU5 Q92729 Q92735 A6H8L1 O00197 P78399 Q59HA4
Accessions AAB07074 CCQ43332 EAX07650 EAX07651 EAX07652 Q92729 AB208855 BAD92092 AK094849 BAG52941 BC033131 BC146655 AAI46656 BM799833 BU687539 CN410555 U71075 AAC51938 U73727 AAB51343 X95712 CAA65016 X97198 CAA65832 XM_006710269 XP_006710332 XM_006710270 XP_006710333 XM_006710272 XP_006710335 XM_006710273 XP_006710336 XM_011540458 XP_011538760 NM_001195001 NP_001181930 NM_005704 NP_005695 NM_133177 NP_573438 NM_133178 NP_573439
Function Tyrosine-protein phosphatase which dephosphorylates CTNNB1. Regulates CTNNB1 function both in cell adhesion and signaling. May function in cell proliferation and migration and play a role in the maintenance of epithelial integrity. May play a role in megakaryocytopoiesis. {ECO:0000269|PubMed:10397721, ECO:0000269|PubMed:12501215, ECO:0000269|PubMed:16574648}.
Subcellular Location Cell junction {ECO:0000269|PubMed:8700514}. Cell membrane {ECO:0000269|PubMed:8700514}; Single-pass type I membrane protein {ECO:0000269|PubMed:8700514}.
Tissue Specificity High levels in brain, pancreas, and skeletal muscle; less in colon, kidney, liver, stomach, and uterus; not expressed in placenta and spleen. Also detected in heart, prostate, lung, thymus, testis and ovary. Ubiquitously expressed in brain. Expressed by hematopoietic stem cells. {ECO:0000269|PubMed:8700514, ECO:0000269|PubMed:8870675, ECO:0000269|PubMed:9070223, ECO:0000269|PubMed:9434160}.

PTPψ (L-20) - sc-67804 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

PTPψ (N-20) - sc-67805 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-PTP lambda antibody - ab13223 from Abcam

Prices $242.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-PTP lambda antibody (ab13223) at 1/500 dilutionLane 1 : Human brain lysateLane 2 : Human kidney lysateLane 3 : Human pancreas lysateLane 4 : Human heart lysateLane 5 : Human brain lysate with Human PTP lambda peptide (ab13230) at 1 µg/mlLane 6 : Human kidney lysate with Human PTP lambda peptide (ab13230) at 1 µg/mlLane 7 : Human pancreas lysate with Human PTP lambda peptide (ab13230) at 1 µg/mlLane 8 : Human heart lysate with Human PTP lambda peptide (ab13230) at 1 µg/mlLysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG H&L (HRP) (ab6721) at 1/5000 dilutionPerformed under reducing conditions.Exposure time : 5 minutesA weak band of predicted size (~160kDa) is observed in human kidney lysate which is quenched by the blocking peptide (ab13230).

Anti-PTPRU Antibody (aa52-67) - LS-C3173 from LifeSpan Bioscience

Prices $265.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

PTP pi/PTPRU Antibody (764209) - MAB7475 from Novus Biologicals

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Mouse
Clonality Monoclonal
Clone 764209
Western blot shows lysates of human brain (cerebellum) tissue and rat brain tissue. PVDF membrane was probed with 0.5 µg/mL of Mouse Anti-Human PTPπ/PTPRU Monoclonal Antibody (Catalog # MAB7475) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF018). A specific band was detected for PTPπ/PTPRU at approximately 180-200 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

PTP pi/PTPRU Antibody - NBP1-81873 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: PTP pi/PTPRU Antibody [NBP1-81873] - Staining of human stomach, lower shows strong cytoplasmic positivity in glandular cells.

Anti-PTPRU antibody produced in rabbit - HPA039832 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-PTPRU: <B>Cat. No. HPA039832</B>: Immunohistochemical staining of human stomach, lower shows strong cytoplasmic positivity in glandular cells.

Anti-PTP-U (N-term) antibody produced in rabbit - SAB1300494 from Sigma-Aldrich

Prices $291.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Human/Rat PTPπ/PTPRU Antibody - MAB7475 from R&D Systems

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Mouse
Clone 764209
Detection of Human and Rat PTPp/PTPRU by Western Blot. Western blot shows lysates of human brain (cerebellum) tissue and rat brain tissue. PVDF membrane was probed with 0.5 µg/mL of Mouse Anti-Human PTPp/PTPRU Monoclonal Antibody (Catalog # MAB7475) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF018 ). A specific band was detected for PTPp/PTPRU at approximately 180-200 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1 .

Human/Rat PTP pi/PTPRU MAb (Clone 764209), Mouse IgG1 - MAB7475-SP from R&D Systems

Host Mouse
Clonality Monoclonal
Clone 764209
Detection of Human and Rat PTPp/PTPRU by Western Blot. Western blot shows lysates of human brain (cerebellum) tissue and rat brain tissue. PVDF membrane was probed with 0.5 µg/mL of Mouse Anti-Human PTPp/PTPRU Monoclonal Antibody (Catalog # MAB7475) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF018). A specific band was detected for PTPp/PTPRU at approximately 180-200 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

PTPRU, Monoclonal Antibody - MBS6002703 from MyBioSource

Prices $580.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3F4

Anti-PTPRU antibody - STJ110773 from St John's Laboratory Ltd

Host Rabbit
Clonality Polyclonal

PTPRU - A8475 from NeoScientific

Prices $220.00, $380.00
Sizes 100 µl, 200 µl
Host Rabbit
Clonality Monoclonal

PTPRU Polyclonal Antibody - A8475 from ABclonal

Prices $130.00, $220.00, $380.00
Sizes 50 µl, 100 µl, 200 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of rat brain cells, using PTPRU antibody.

PTPRU, Polyclonal Antibody - MBS9128213 from MyBioSource

Prices $230.00, $305.00, $460.00
Sizes 50 µl, 100 µl, 200 µl
Host Rabbit
Clonality Polyclonal

PTPRU Antibody - abx006232 from Abbexa

Host Rabbit
Clonality Polyclonal

PTPRO - BT-AP6003 from Nordic BioSite

Host Rabbit
Clonality Polyclonal
Clone polyclonal

Anti-PTPRU monoclonal antibody, clone 875300 - CABT-BL3064 from Creative Diagnostics

Host Mouse
Clonality Monoclonal
Clone 875300

Protein Tyrosine Phosphatase Receptor Type U, Polyclonal Antibody - MBS2034081 from MyBioSource

Prices $160.00, $320.00, $495.00
Sizes 20 µg, 100 µg, 200 µg
Host Rabbit
Clonality Polyclonal

Protein Tyrosine Phosphatase Receptor Type U (PTPRU), Polyclonal Antibody - MBS2072043 from MyBioSource

Prices $900.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Protein Tyrosine Phosphatase Receptor Type U (PTPRU), Polyclonal Antibody - MBS2072044 from MyBioSource

Prices $380.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Protein Tyrosine Phosphatase Receptor Type U (PTPRU), Polyclonal Antibody - MBS2072045 from MyBioSource

Prices $465.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Protein Tyrosine Phosphatase Receptor Type U (PTPRU), Polyclonal Antibody - MBS2072046 from MyBioSource

Prices $605.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Protein Tyrosine Phosphatase Receptor Type U (PTPRU), Polyclonal Antibody - MBS2072047 from MyBioSource

Prices $380.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Protein Tyrosine Phosphatase Receptor Type U (PTPRU), Polyclonal Antibody - MBS2072048 from MyBioSource

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
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