| Gene Symbol |
MED22
|
| Entrez Gene |
6837
|
| Alt Symbol |
MED24, SURF5, surf-5
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
mediator complex subunit 22
|
| Other Description |
mediator of RNA polymerase II transcription subunit 22|surfeit locus protein 5
|
| Swissprots |
O76072 B3KW83 B3KWX4 Q15528 Q5T8U0
|
| Accessions |
CAA12052 CAA12053 CAA76691 CAI12827 CAI12829 CAI12830 CAI12831 EAW88056 EAW88057 EAW88058 EAW88059 EAW88060 Q15528 AJ224358 CAA11915 AJ224359 CAA11916 AJ224360 CAA11917 AK124518 BAG54045 AK126069 BAG54286 BC024225 AAH24225 BC040111 AAH40111 BI756582 GD160955 HQ448554 ADQ33033 HY154869 X85178 CAA59462 NM_133640 NP_598395 NM_181491 NP_852468 NM_006752
|
| Function |
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
|
| Subcellular Location |
Nucleus {ECO:0000305}.
|
