Gene Symbol | MED22 |
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Entrez Gene | 6837 |
Alt Symbol | MED24, SURF5, surf-5 |
Species | Human |
Gene Type | protein-coding |
Description | mediator complex subunit 22 |
Other Description | mediator of RNA polymerase II transcription subunit 22|surfeit locus protein 5 |
Swissprots | O76072 B3KW83 B3KWX4 Q15528 Q5T8U0 |
Accessions | CAA12052 CAA12053 CAA76691 CAI12827 CAI12829 CAI12830 CAI12831 EAW88056 EAW88057 EAW88058 EAW88059 EAW88060 Q15528 AJ224358 CAA11915 AJ224359 CAA11916 AJ224360 CAA11917 AK124518 BAG54045 AK126069 BAG54286 BC024225 AAH24225 BC040111 AAH40111 BI756582 GD160955 HQ448554 ADQ33033 HY154869 X85178 CAA59462 NM_133640 NP_598395 NM_181491 NP_852468 NM_006752 |
Function | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. |
Subcellular Location | Nucleus {ECO:0000305}. |
Human SURF5 full length protein - ab159618 from Abcam
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Human SURF5 protein fragment - ab159619 from Abcam
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MED22 Antibody Blocking Peptide - LS-E1853 from LifeSpan Bioscience
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MED22 Antibody Blocking Peptide - LS-E24111 from LifeSpan Bioscience
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MED24 / TRAP100 Blocking Peptide - LS-E26452 from LifeSpan Bioscience
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Recombinant Human SURF5 Protein - H00006837-Q01 from Novus Biologicals
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Recombinant Human MED24 Protein - H00009862-Q01 from Novus Biologicals
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Recombinant Human SURF5 Protein - H00006837-P01 from Novus Biologicals
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Recombinant Human MED24 Protein - H00009862-P01 from Novus Biologicals
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MED22-Antibody-N-term-Blocking-peptide - BP12666a from Abgent, a WuXi AppTec company
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MED22 Blocking Peptide - abx064213 from Abbexa
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MED22 / SURF5 - H00006837-P01-10 from Acris Antibodies
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MED22 / SURF5 - H00006837-P01-25 from Acris Antibodies
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MED22 / SURF5 - H00006837-Q01-10 from Acris Antibodies
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MED22 / SURF5 - H00006837-Q01-25 from Acris Antibodies
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MED22 fusion protein - Ag10102 from Proteintech Group
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MED22 fusion protein - Ag9800 from Proteintech Group
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Recombinant Human MED22, GST-tagged - MED22-808H from Creative Biomart
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MED22 Blocking Peptide - CBP3019 from Cohesion Biosciences
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Recombinant Mediator of RNA polymerase II transcription subunit 22(mdt-22) - CSB-YP714027CXX CSB-EP714027CXX CSB-BP714027CXX CSB-MP714027CXX from Cusabio
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Recombinant Human Mediator of RNA polymerase II transcription subunit 22(MED22) - CSB-YP620882HU CSB-EP620882HU CSB-BP620882HU CSB-MP620882HU from Cusabio
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MED22 / SURF5 (transcript variant c) - TP308015 from Acris Antibodies
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SURF5 Recombinant Protein Antigen - NBP1-87818PEP from Novus Biologicals
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MED22 Peptide, Human - M34GP09367H from Creative Peptides
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MED24 Peptide, Human - M34GP09369H from Creative Peptides
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