EIF4G2

Gene Symbol EIF4G2
Entrez Gene 1982
Alt Symbol AAG1, DAP5, NAT1, P97
Species Human
Gene Type protein-coding
Description eukaryotic translation initiation factor 4 gamma, 2
Other Description DAP-5|aging-associated protein 1|death-associated protein 5|eIF-4-gamma 2|eIF-4G 2|eIF4G 2|eukaryotic translation initiation factor 4 gamma 2|eukaryotic translation initiation factor 4G-like 1
Swissprots Q58EZ2 Q49A79 Q2NKW9 Q0VH01 P78344 Q0VH00 O60877 Q8NI71 Q53EU1 Q96C16 P78404
Accessions EAW68552 EAW68553 EAW68554 EAW68555 P78344 AB063323 BAB93515 AB073654 BAE45728 AB209267 BAD92504 AI362365 AK123338 AK223548 BAD97268 AK302886 BAG64064 AK310387 AK310738 AY513274 AAT08027 BC014930 AAH14930 BC018746 AAH18746 BC018975 AAH18975 BC039851 AAH39851 BC043149 AAH43149 BC065276 AAH65276 BC111415 AAI11416 BC111548 AAI11549 BX647799 DB072494 DB231980 DB272352 U73824 AAB49973 U76111 AAC51166 X89713 CAA61857 NM_001042559 NP_001036024 NM_001172705 NP_001166176 NM_001418 NP_001409
Function Appears to play a role in the switch from cap-dependent to IRES-mediated translation during mitosis, apoptosis and viral infection. Cleaved by some caspases and viral proteases. {ECO:0000269|PubMed:11511540, ECO:0000269|PubMed:11943866, ECO:0000269|PubMed:9032289, ECO:0000269|PubMed:9049310}.
Tissue Specificity Ubiquitously expressed in all adult tissues examined, with high levels in skeletal muscle and heart. Also expressed in fetal brain, lung, liver and kidney. {ECO:0000269|PubMed:9030685, ECO:0000269|PubMed:9032289, ECO:0000269|PubMed:9049310}.
Top Pathways RNA transport

eIF4G2/p97 (D88B6) XP ® Rabbit mAb - 5169 from Cell Signaling Technology

Prices $277.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D88B6
Western blot analysis of extracts from various cell types using eIF4G2/p97 (D88B6) XP ® Rabbit mAb.

eIF4G2/p97 (D1A10) Rabbit mAb - 3468 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D1A10
Western blot analysis of extracts from various cell types using eIF4G2/p97 (D1A10) Rabbit mAb.

eIF4G2/p97 Antibody - 2182 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from human (Jurkat and HeLa), mouse (NIH/3T3 and L929) and rat (C6 and PC12) cells, using eIF4G2/p97 Antibody.

DAP-5 (B-1) - sc-374236 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
DAP-5 (B-1): sc-374236. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.

DAP-5 (B-8) - sc-137131 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
DAP-5 (B-8): sc-137131. Western blot analysis of DAP-5 expression in HeLa (A), MCF7 (B) and SW480 (C) nuclear extracts.

DAP-5 (C-17) - sc-31679 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
DAP-5 (C-17): sc-31679. Western blot analysis of DAP-5 expression in IFN-γ-induced HeLa (A), untreated HeLa (B), MCF7 (C) and K-562 (D) nuclear extracts.

DAP-5 (F-2) - sc-137011 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
DAP-5 (F-2): sc-137011. Western blot analysis of DAP-5 expression in MCF7 (A), SW480 (B), K-562 (C) and Sol8 (D) nuclear extracts.

DAP-5 (G-20) - sc-13736 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
DAP-5 (G-20): sc-13736. Immunofluorescence staining of methanol-fixed HeLa cells (A) and immunoperoxidase staining of formalin-fixed, paraffin-embedded human breast tumor (B) showing cytoplasmic staining.

DAP-5 (K-15) - sc-31677 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
DAP-5 (K-15): sc-31677. Immunoperoxidase staining of formalin fixed, paraffin-embedded human upper stomach tissue showing cytoplasmic staining of glandular cells.

DAP-5 (H-300) - sc-28224 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
DAP-5 (H-300): sc-28224. Western blot analysis of DAP-5 expression in HeLa (A) and MCF7 (B) nuclear extracts.

DAP-5 (35) - sc-135999 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Mouse
Clonality Monoclonal
DAP-5 (35): sc-135999. Western blot analysis of DAP-5 expression in HeLa whole cell lysate.

Anti-DAP5 antibody - ab2556 from Abcam

Prices $359.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-DAP5 antibody - ab54972 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
DAP5 antibody (ab54972) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human heart.

Anti-DAP5 antibody - ab11929 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
DAP-5 detection by Western blot. The analysis of 10 µg of total cell extract from Jurkat cells with the ab11929 at a 1 µg/ml dilution.

Anti-DAP5 antibody - ab69635 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-DAP5 antibody (ab69635) at 1/500 dilutionLane 1 : Extracts from A549 cellsLane 2 : Extracts from A549 cells with immunising peptide at 5 µgLysates/proteins at 5 µg per lane.

Anti-DAP-5 / EIF4G2 Antibody - LS-C332278 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of paraffin-embedded human colon cancer tissue using EIF4G2 antibody.

Anti-DAP-5 / EIF4G2 Antibody (aa12-44) - LS-C344233 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of lysate from K562 cell line with EIF4G2 Antibody. Antibody was diluted at 1:1000. A goat anti-rabbit IgG H&L (HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35 ug.

Anti-DAP-5 / EIF4G2 Antibody (aa125-175) - LS-C286879 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human DAP5 by Immunohistochemistry. Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-DAP5 used at a dilution of 1:100. Detection:Red-fluorescent Goat anti-Rabbit IgG-heavy and light chain cross-adsorbed Antibody DyLight 594 Conjugated (A120-601D4) used at a dilution of 1:100.

Anti-DAP-5 / EIF4G2 Antibody (clone 3B5) - LS-C133164 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3B5
Immunoperoxidase of monoclonal antibody to EIF4G2 on formalin-fixed paraffin-embedded human heart. [antibody concentration 3 ug/ml].

Anti-DAP-5 / EIF4G2 Antibody (aa796-812, clone 39C534.1) IHC-plus™ - LS-B2026 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 39C534.1
Anti-EIF4G2 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2026 concentration 10 ug/ml.

Anti-DAP-5 / EIF4G2 Antibody IHC-plus™ - LS-B4208 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-EIF4G2 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4208 concentration 10 ug/ml.

Anti-DAP-5 / EIF4G2 Antibody (aa766-815) IHC-plus™ - LS-B944 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-EIF4G2 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B944 concentration 5 ug/ml.

Anti-DAP-5 / EIF4G2 Antibody (aa805) - LS-C14799 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-DAP-5 / EIF4G2 Antibody (aa796-812) - LS-C14800 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-DAP-5 / EIF4G2 Antibody (aa144-193) - LS-C101837 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
EIF4G2 antibody LS-C101837 Western blot of 721_B cell lysate.
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