Gene Symbol | EIF4G2 |
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Entrez Gene | 1982 |
Alt Symbol | AAG1, DAP5, NAT1, P97 |
Species | Human |
Gene Type | protein-coding |
Description | eukaryotic translation initiation factor 4 gamma, 2 |
Other Description | DAP-5|aging-associated protein 1|death-associated protein 5|eIF-4-gamma 2|eIF-4G 2|eIF4G 2|eukaryotic translation initiation factor 4 gamma 2|eukaryotic translation initiation factor 4G-like 1 |
Swissprots | Q58EZ2 Q49A79 Q2NKW9 Q0VH01 P78344 Q0VH00 O60877 Q8NI71 Q53EU1 Q96C16 P78404 |
Accessions | EAW68552 EAW68553 EAW68554 EAW68555 P78344 AB063323 BAB93515 AB073654 BAE45728 AB209267 BAD92504 AI362365 AK123338 AK223548 BAD97268 AK302886 BAG64064 AK310387 AK310738 AY513274 AAT08027 BC014930 AAH14930 BC018746 AAH18746 BC018975 AAH18975 BC039851 AAH39851 BC043149 AAH43149 BC065276 AAH65276 BC111415 AAI11416 BC111548 AAI11549 BX647799 DB072494 DB231980 DB272352 U73824 AAB49973 U76111 AAC51166 X89713 CAA61857 NM_001042559 NP_001036024 NM_001172705 NP_001166176 NM_001418 NP_001409 |
Function | Appears to play a role in the switch from cap-dependent to IRES-mediated translation during mitosis, apoptosis and viral infection. Cleaved by some caspases and viral proteases. {ECO:0000269|PubMed:11511540, ECO:0000269|PubMed:11943866, ECO:0000269|PubMed:9032289, ECO:0000269|PubMed:9049310}. |
Tissue Specificity | Ubiquitously expressed in all adult tissues examined, with high levels in skeletal muscle and heart. Also expressed in fetal brain, lung, liver and kidney. {ECO:0000269|PubMed:9030685, ECO:0000269|PubMed:9032289, ECO:0000269|PubMed:9049310}. |
Top Pathways | RNA transport |
Human DAP5 protein fragment - ab158342 from Abcam
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DAP-5 / EIF4G2 Antibody Blocking Peptide - LS-E14711 from LifeSpan Bioscience
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DAP-5 / EIF4G2 Antibody Blocking Peptide - LS-E14710 from LifeSpan Bioscience
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NAT1 / AAC1 Antibody Blocking Peptide - LS-E2243 from LifeSpan Bioscience
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NAT1 / AAC1 Antibody Blocking Peptide - LS-E26743 from LifeSpan Bioscience
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Recombinant Human DAP5 Protein - H00001982-Q01 from Novus Biologicals
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NAT1 Recombinant Protein - H00000009-P01 from Novus Biologicals
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NAT1 Partial Recombinant Protein - H00000009-Q01 from Novus Biologicals
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Recombinant Human NAT1 Protein - NBP1-72356 from Novus Biologicals
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Human NAT1 protein - orb168900 from Biorbyt
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NAT1 Immunizing peptide - orb17046 from Biorbyt
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EIF4G2 Blocking Peptide - 33R-4390 from Fitzgerald
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EIF4G2 Blocking Peptide - 33R-7233 from Fitzgerald
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EIF4G2 Blocking Peptide - abx062573 from Abbexa
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eIF4G2 / DAP5 - H00001982-Q01-10 from Acris Antibodies
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eIF4G2 / DAP5 - H00001982-Q01-25 from Acris Antibodies
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EIF4G2 fusion protein - ag12080 from Proteintech Group
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EIF4G2 fusion protein - Ag12125 from Proteintech Group
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EIF4G2 Blocking Peptide - CBP1379 from Cohesion Biosciences
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DAP-5 (N65) Peptide - BS2414P from Bioworld Technology
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Recombinant Human Eukaryotic translation initiation factor 4 gamma 2(EIF4G2) ,partial - CSB-YP007569HU CSB-EP007569HU CSB-BP007569HU CSB-MP007569HU from Cusabio
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NAT1 Recombinant Protein Antigen - NBP2-13641PEP from Novus Biologicals
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DAP5 Recombinant Protein Antigen - NBP1-85311PEP from Novus Biologicals
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DAP5 Recombinant Protein Antigen - NBP1-85310PEP from Novus Biologicals
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EIF4G2-Blocking-Peptide-N-term - BP20594a from Abgent, a WuXi AppTec company
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