Gene Symbol | HEXIM2 |
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Entrez Gene | 124790 |
Alt Symbol | L3 |
Species | Human |
Gene Type | protein-coding |
Description | hexamethylene bis-acetamide inducible 2 |
Other Description | MAQ1 paralog|hexamethylene bis-acetamide-inducible protein 2|hexamethylene-bis-acetamide-inducible transcript 2|protein HEXIM2 |
Swissprots | D3DX66 Q96MH2 |
Accessions | EAW51541 EAW51542 Q96MH2 AA223138 AK056946 BAB71319 AK096785 AW340131 AY598322 AAT06733 BC003531 AAH03531 BC012474 AAH12474 BC025970 AAH25970 BG696988 BI829228 BI829844 BP209696 BP398345 BU501076 CA312679 CN425800 DB160394 HQ447675 ADQ32160 HY007091 XM_006721687 XP_006721750 XM_011524302 XP_011522604 XM_011524303 XP_011522605 XM_011524304 XP_011522606 XM_011524305 XP_011522607 XM_011524306 XP_011522608 XM_011524307 XP_011522609 XM_011524308 XP_011522610 NM_001303436 NP_001290365 NM_001303437 NP_001290366 NM_001303438 NP_001290367 NM_001303439 NP_001290368 NM_001303440 NP_001290369 NM_001303441 NP_001290370 NM_001303442 NP_001290371 NM_001303443 NP_001290372 NM_001303444 NP_001290373 NM_144608 NP_653209 |
Function | Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. {ECO:0000269|PubMed:15713661, ECO:0000269|PubMed:15713662}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:15994294}. |
Tissue Specificity | Ubiquitously expressed with higher expression in testis. HEXIM1 and HEXIM2 are differentially expressed. {ECO:0000269|PubMed:15713661}. |
HEXIM2 (A-7) - sc-390814 from Santa Cruz Biotechnology
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HEXIM2 (C-16) - sc-48874 from Santa Cruz Biotechnology
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HEXIM2 (H-90) - sc-98901 from Santa Cruz Biotechnology
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HEXIM2 (M-90) - sc-98902 from Santa Cruz Biotechnology
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HEXIM2 (N-17) - sc-48877 from Santa Cruz Biotechnology
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Anti-HEXIM2 antibody - ab127710 from Abcam
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Anti-HEXIM2 antibody - ab46528 from Abcam
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Anti-HEXIM2 antibody - ab112041 from Abcam
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Anti-HEXIM2 Antibody - LS-C314013 from LifeSpan Bioscience
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Anti-HEXIM2 Antibody (aa1-50) - LS-C289777 from LifeSpan Bioscience
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Anti-HEXIM2 Antibody (N-Terminus) - LS-C110607 from LifeSpan Bioscience
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Anti-HEXIM2 Antibody - LS-C155665 from LifeSpan Bioscience
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HEXIM2 Antibody - NBP1-93877 from Novus Biologicals
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HEXIM2 Antibody - NBP2-16812 from Novus Biologicals
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HEXIM2 Antibody - NBP1-93876 from Novus Biologicals
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HEXIM2 Polyclonal Antibody - bs-15469R from Bioss
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FAAH1 Polyclonal Antibody - bs-5104R from Bioss
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Anti-HEXIM2 antibody produced in rabbit - SAB2702124 from Sigma-Aldrich
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Anti-HEXIM2 antibody produced in rabbit - HPA023323 from Sigma-Aldrich
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Anti-HEXIM2 antibody produced in rabbit - SAB2101031 from Sigma-Aldrich
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Anti-HEXIM2 antibody produced in rabbit - HPA028455 from Sigma-Aldrich
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HEXIM2 antibody - N-terminal region (ARP41121_P050) - ARP41121_P050 from Aviva Systems Biology
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HEXIM2 antibody - GTX121524 from GeneTex
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HEXIM2 antibody, N-term - GTX47216 from GeneTex
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Anti -Hexim2 (Protein HEXIM2, Hexamethylene bis-acetamide-inducible Protein 2, ORF Names:L3) - 223210 from USBiological Life Science
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