Gene Symbol | KIF1B |
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Entrez Gene | 23095 |
Alt Symbol | CMT2, CMT2A, CMT2A1, HMSNII, KLP, NBLST1 |
Species | Human |
Gene Type | protein-coding |
Description | kinesin family member 1B |
Other Description | kinesin superfamily protein KIF1B|kinesin-like protein KIF1B |
Swissprots | Q9P280 A6NFS8 O60333 Q9BV80 Q4VXC5 Q4VXC6 Q4VXC3 A6NKQ4 Q96Q94 Q4VXC4 |
Accessions | CAC16629 EAW71641 EAW71642 EAW71643 EAW71644 EAW71645 O60333 AA609163 AB011163 BAA25517 AB017133 BAB69038 AB040881 BAA95972 AB088210 BAE02543 AB088211 BAE02544 AB088212 BAE02545 AB088213 BAE02546 AF257176 AAK49332 AK022977 BAB14341 AK023184 AK025761 AK025771 AK074279 AK297439 BAG59865 AK308121 AU121683 AV726155 AY043362 AAK85155 AY139835 AAN17742 BC001415 AAH01415 BC028114 BC040017 BC047632 BC063684 BC073883 BC094856 BC115395 AAI15396 BF940695 BI601300 BP239973 BT007174 AAP35838 BU626971 DA113609 DA485632 DA774937 NM_015074 NP_055889 NM_183416 NP_904325 |
Function | Motor for anterograde transport of mitochondria. Has a microtubule plus end-directed motility. Isoform 2 is required for induction of neuronal apoptosis. {ECO:0000269|PubMed:18334619}. |
Subcellular Location | Cytoplasmic vesicle {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Mitochondrion {ECO:0000269|PubMed:16225668}. Note=Colocalizes with synaptophysin at synaptic cytoplasmic transport vesicles in the neurites of hippocampal neurons. {ECO:0000250}. |
Tissue Specificity | Isoform 3 is abundant in the skeletal muscle. It is also expressed in fetal brain, lung and kidney, and adult heart, placenta, testis, ovary and small intestine. Isoform 2 is abundant in the brain and also expressed in fetal heart, lung, liver and kidney, and adult skeletal muscle, placenta, liver, kidney, heart, spleen, thymus, prostate, testis, ovary, small intestine, colon and pancreas. {ECO:0000269|PubMed:10762626, ECO:0000269|PubMed:11526494, ECO:0000269|PubMed:12888911}. |
Phospho-KIF1B (Ser1487) Antibody - 11993 from Cell Signaling Technology
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KIF1B (E-12) - sc-376246 from Santa Cruz Biotechnology
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KIF1B (H-190) - sc-28540 from Santa Cruz Biotechnology
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KIF1B (L-20) - sc-18739 from Santa Cruz Biotechnology
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Anti-KIF1B antibody - ab69614 from Abcam
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Anti-KIF1B antibody - ab72108 from Abcam
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Anti-KIF1B / CMT2 Antibody (C-Terminus) - LS-C71334 from LifeSpan Bioscience
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Anti-KIF1B / CMT2 Antibody (C-Terminus) - LS-C287886 from LifeSpan Bioscience
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Anti-KIF1B / CMT2 Antibody - LS-C335694 from LifeSpan Bioscience
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Anti-KIF1B / CMT2 Antibody (aa1575-1625) - LS-C71333 from LifeSpan Bioscience
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Anti-KIF1B / CMT2 Antibody (aa1575-1625) - LS-C287884 from LifeSpan Bioscience
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KIF1B Antibody - NB100-57493 from Novus Biologicals
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KIF1B Antibody - NB100-57494 from Novus Biologicals
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KIF1B Antibody - NBP1-85536 from Novus Biologicals
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KIF1B Antibody - H00023095-B01 from Novus Biologicals
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Anti-KIF1B antibody produced in rabbit - HPA026434 from Sigma-Aldrich
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MAD2L1BP antibody - GTX82363 from GeneTex
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KIF1B antibody - 70R-18114 from Fitzgerald
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Anti -KIF1B (Kinesin Family Member 1B, Charcot Marie Tooth Neuropathy 2A, CMT2A, CMT2A1,D4Mil1e, HMSNII, Hereditary Motor Sensory Neuropathy II, KIF1B p130, KIF1B p204,Kinesin-like Protein KIF1B, KLP) - K1759-05 from USBiological Life Science
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Anti -KIF1B (Kinesin Family Member 1B, Charcot Marie Tooth Neuropathy 2A, CMT2A, CMT2A1,D4Mil1e, HMSNII, Hereditary Motor Sensory Neuropathy II, KIF1B p130, KIF1B p204,Kinesin-like Protein KIF1B, KLP) - K1759-05A from USBiological Life Science
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Anti -KIF1B (Kinesin Family Member 1B, KLP, CMT2, CMT2A, CMT2A1, HMSNII, NBLST1) - 219042 from USBiological Life Science
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KIF1B Polyclonal Antibody - A6638 from ABclonal
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KIF1B Antibody - abx005089 from Abbexa
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KIF1B antibody - 15263-1-AP from Acris Antibodies
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KIF1B antibody - H00023095-B01 from Acris Antibodies
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