Gene Symbol | KIF1B |
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Entrez Gene | 23095 |
Alt Symbol | CMT2, CMT2A, CMT2A1, HMSNII, KLP, NBLST1 |
Species | Human |
Gene Type | protein-coding |
Description | kinesin family member 1B |
Other Description | kinesin superfamily protein KIF1B|kinesin-like protein KIF1B |
Swissprots | Q9P280 A6NFS8 O60333 Q9BV80 Q4VXC5 Q4VXC6 Q4VXC3 A6NKQ4 Q96Q94 Q4VXC4 |
Accessions | CAC16629 EAW71641 EAW71642 EAW71643 EAW71644 EAW71645 O60333 AA609163 AB011163 BAA25517 AB017133 BAB69038 AB040881 BAA95972 AB088210 BAE02543 AB088211 BAE02544 AB088212 BAE02545 AB088213 BAE02546 AF257176 AAK49332 AK022977 BAB14341 AK023184 AK025761 AK025771 AK074279 AK297439 BAG59865 AK308121 AU121683 AV726155 AY043362 AAK85155 AY139835 AAN17742 BC001415 AAH01415 BC028114 BC040017 BC047632 BC063684 BC073883 BC094856 BC115395 AAI15396 BF940695 BI601300 BP239973 BT007174 AAP35838 BU626971 DA113609 DA485632 DA774937 NM_015074 NP_055889 NM_183416 NP_904325 |
Function | Motor for anterograde transport of mitochondria. Has a microtubule plus end-directed motility. Isoform 2 is required for induction of neuronal apoptosis. {ECO:0000269|PubMed:18334619}. |
Subcellular Location | Cytoplasmic vesicle {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Mitochondrion {ECO:0000269|PubMed:16225668}. Note=Colocalizes with synaptophysin at synaptic cytoplasmic transport vesicles in the neurites of hippocampal neurons. {ECO:0000250}. |
Tissue Specificity | Isoform 3 is abundant in the skeletal muscle. It is also expressed in fetal brain, lung and kidney, and adult heart, placenta, testis, ovary and small intestine. Isoform 2 is abundant in the brain and also expressed in fetal heart, lung, liver and kidney, and adult skeletal muscle, placenta, liver, kidney, heart, spleen, thymus, prostate, testis, ovary, small intestine, colon and pancreas. {ECO:0000269|PubMed:10762626, ECO:0000269|PubMed:11526494, ECO:0000269|PubMed:12888911}. |
Human KIF1B peptide - ab74827 from Abcam
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Human KIF1B protein fragment - ab132804 from Abcam
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CMT2 / MAD2L1BP Antibody Blocking Peptide - LS-E4388 from LifeSpan Bioscience
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CMT2 / MAD2L1BP Antibody Blocking Peptide - LS-E22440 from LifeSpan Bioscience
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Recombinant Human KIF1B Protein - H00023095-P01 from Novus Biologicals
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KIF1B - H00023095-P01-10 from Acris Antibodies
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KIF1B - H00023095-P01-25 from Acris Antibodies
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KIF1B fusion protein - Ag7263 from Proteintech Group
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Recombinant Human KIF1B, His-tagged - KIF1B-364H from Creative Biomart
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MAD2L1BP 1-274aa - CMB-1274 from Reagent Proteins
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Recombinant Human Kinesin-like protein KIF1B(KIF1B) ,partial - CSB-YP012319HU CSB-EP012319HU CSB-BP012319HU CSB-MP012319HU from Cusabio
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KIF1B Protein - NBP1-85536PEP from Novus Biologicals
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KIF1B Peptide, Human - M34GP08182H from Creative Peptides
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PDZ domain scaffold protein anti-Human KIF1Bα - SPD-L164 from Creative Biolabs
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Kinesin-like protein KIF1B (KIF1B), partial, Recombinant Protein - MBS1029210 from MyBioSource
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