RAB11B

Gene Symbol	RAB11B
Entrez Gene	9230
Alt Symbol	H-YPT3
Species	Human
Gene Type	protein-coding
Description	RAB11B, member RAS oncogene family
Other Description	GTP-binding protein YPT3|RAB11B, member of RAS oncogene family|ras-related protein Rab-11B
Swissprots	Q2YDT2 Q8NI07 Q15907 Q6FHR0 B2R7I4 Q6FI42 B4DMK0 Q5U0I1 A5YM50 D6W671
Accessions	EAW68925 EAW68926 EAW68927 Q15907 AF498947 AAM21095 AK225036 AK225642 AK297498 BAG59912 AK310573 AK312994 BAG35831 BC110081 AAI10082 BP367041 BP396219 BT019535 AAV38342 BT019536 AAV38343 BX647356 CR536494 CAG38733 CR541691 CAG46492 CX787570 D38516 EF560724 ABQ59034 GQ129215 ACT64349 GQ129216 ACT64350 X79780 CAA56176 NM_004218 NP_004209
Function	The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab plays a role in endocytic recycling, regulating apical recycling of several transmembrane proteins including cystic fibrosis transmembrane conductance regulator/CFTR, epithelial sodium channel/ENaC, potassium voltage- gated channel, and voltage-dependent L-type calcium channel. May also regulate constitutive and regulated secretion, like insulin granule exocytosis. Required for melanosome transport and release from melanocytes. Also regulates V-ATPase intracellular transport in response to extracellular acidosis. {ECO:0000269|PubMed:14627637, ECO:0000269|PubMed:19029296, ECO:0000269|PubMed:19244346, ECO:0
Subcellular Location	Recycling endosome membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cytoplasmic vesicle, phagosome membrane {ECO:0000305|PubMed:21255211}; Lipid-anchor {ECO:0000305|PubMed:21255211}; Cytoplasmic side {ECO:0000305|PubMed:21255211}. Note=Recruited to phagosomes containing S.aureus.
Top Pathways	Endocytosis, Vasopressin-regulated water reabsorption, AMPK signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Rab11 peptide - ab41779 from Abcam Category Peptide Species Human

Human Rab11 peptide - ab66706 from Abcam Category Peptide

Recombinant Human Rab11 Protein - H00009230-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human Rab11 Protein - H00009230-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

RAB11B-Antibody-C-term-Blocking-peptide - BP12943b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human RAB11B (His Tag) protein - orb232381 from Biorbyt Category Protein Prices $323.00, $646.00 Sizes 20 μg, 100 μg Species Human

RAB11B Blocking Peptide - 33R-3953 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

RAB11B - H00009230-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

RAB11B - H00009230-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

RAB11B - H00009230-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

RAB11B - H00009230-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Human RAB11B Protein (His Tag) - 15636-H07H-20 from Sino Biological Category Protein Prices $138.00, $348.00 Sizes 20 µg, 100 µg Source Human Cells Species Human

Recombinant Human Ras-related protein Rab-11B(RAB11B) - CSB-YP614903HU CSB-EP614903HU CSB-BP614903HU CSB-MP614903HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

RAB11B Peptide - abx165029 from Abbexa Category Peptide Species Human, Mouse, Rat

RAB11B - TP322162 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Human RAB11B Protein (His Tag) - PKSH030533 from Elabscience Category Protein Source Human Cell Species Human

Recombinant Human RAB11B Protein, His-tagged - RAB11B-706H from Creative Biomart Category Protein Source HEK293 Species Human

RAB11B Peptide, Human - M34GP12815H from Creative Peptides Category Peptide Source Synthetic. Species Human

RAB11B Recombinant Protein Antigen - NBP2-58127PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

RAB11B, Recombinant Protein - MBS2545225 from MyBioSource Category Protein Prices $375.00, $905.00 Sizes 20 µg, 100 µg Source Human Cells

Ras-related protein Rab-11B (RAB11B), Recombinant Protein - MBS1378061 from MyBioSource Category Protein Prices $965.00, $965.00, $1,190.00, $1,190.00, $1,450.00, $1,450.00, $1,915.00, $1,915.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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