RAB11B

Gene Symbol	RAB11B
Entrez Gene	9230
Alt Symbol	H-YPT3
Species	Human
Gene Type	protein-coding
Description	RAB11B, member RAS oncogene family
Other Description	GTP-binding protein YPT3|RAB11B, member of RAS oncogene family|ras-related protein Rab-11B
Swissprots	Q2YDT2 Q8NI07 Q15907 Q6FHR0 B2R7I4 Q6FI42 B4DMK0 Q5U0I1 A5YM50 D6W671
Accessions	EAW68925 EAW68926 EAW68927 Q15907 AF498947 AAM21095 AK225036 AK225642 AK297498 BAG59912 AK310573 AK312994 BAG35831 BC110081 AAI10082 BP367041 BP396219 BT019535 AAV38342 BT019536 AAV38343 BX647356 CR536494 CAG38733 CR541691 CAG46492 CX787570 D38516 EF560724 ABQ59034 GQ129215 ACT64349 GQ129216 ACT64350 X79780 CAA56176 NM_004218 NP_004209
Function	The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab plays a role in endocytic recycling, regulating apical recycling of several transmembrane proteins including cystic fibrosis transmembrane conductance regulator/CFTR, epithelial sodium channel/ENaC, potassium voltage- gated channel, and voltage-dependent L-type calcium channel. May also regulate constitutive and regulated secretion, like insulin granule exocytosis. Required for melanosome transport and release from melanocytes. Also regulates V-ATPase intracellular transport in response to extracellular acidosis. {ECO:0000269|PubMed:14627637, ECO:0000269|PubMed:19029296, ECO:0000269|PubMed:19244346, ECO:0
Subcellular Location	Recycling endosome membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cytoplasmic vesicle, phagosome membrane {ECO:0000305|PubMed:21255211}; Lipid-anchor {ECO:0000305|PubMed:21255211}; Cytoplasmic side {ECO:0000305|PubMed:21255211}. Note=Recruited to phagosomes containing S.aureus.
Top Pathways	Endocytosis, Vasopressin-regulated water reabsorption, AMPK signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Rab11b Antibody - 2414 from Cell Signaling Technology Prices $246.00 Sizes 100 µl (10 western blots) Host Rabbit Clonality Polyclonal

Rab 11B (K-13) - sc-26591 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Rab 11B (P-22) - sc-133937 from Santa Cruz Biotechnology Prices $279.00 Sizes 50 µg/0.5 ml Host Rabbit Clonality Polyclonal

Anti-Rab11 antibody - ab3612 from Abcam Prices $400.00 Sizes 200 µg Host Rabbit Clonality Polyclonal

Anti-Rab11 antibody - ab168559 from Abcam Prices $376.00 Sizes 50 µg Host Mouse Clonality Polyclonal

Anti-Rab11 antibody - N-terminal - ab195976 from Abcam Prices $359.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-RAB11B antibody [EPR12719] - ab176344 from Abcam Prices $357.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR12719

Anti-RAB11B antibody [EPR12725] - ab175925 from Abcam Prices $357.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR12725

Anti-RAB11B Antibody - LS-C131773 from LifeSpan Bioscience Prices $405.00 Sizes 100 µg Host Rat Clonality Monoclonal

Anti-RAB11B Antibody - LS-C131772 from LifeSpan Bioscience Prices $405.00 Sizes 100 µg Host Rat Clonality Monoclonal

Anti-RAB11B Antibody (clone KT80) - LS-C193543 from LifeSpan Bioscience Prices $355.00 Sizes 100 µg Host Rat Clonality Monoclonal Clone KT80

Anti-RAB11B Antibody (C-Terminus) - LS-C348299 from LifeSpan Bioscience Prices $375.00 Sizes 200 µl Host Goat Clonality Polyclonal

Anti-RAB11B Antibody (C-Terminus) - LS-C81194 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-RAB11B Antibody (aa164-213) - LS-C199510 from LifeSpan Bioscience Prices $315.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-RAB11B Antibody (C-Terminus) - LS-C348298 from LifeSpan Bioscience Prices $375.00 Sizes 200 µl Host Goat Clonality Polyclonal

Anti-RAB11B Antibody (aa164-193) - LS-C162356 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-RAB11B Antibody (clone KT81) - LS-C193544 from LifeSpan Bioscience Prices $355.00 Sizes 100 µg Host Rat Clonality Monoclonal Clone KT81

RAB11B Antibody - NBP2-15085 from Novus Biologicals Prices $329.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Rab11 Antibody - NBP1-58933 from Novus Biologicals Prices $329.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Rab11 Antibody - H00009230-B02P from Novus Biologicals Prices $359.00 Sizes 50 µg Host Mouse Clonality Polyclonal

Rab11 Antibody (2F1) - H00009230-M03A from Novus Biologicals Prices $349.00 Sizes 200 µl Host Mouse Clonality Monoclonal Clone 2F1

Anti-RAB11B antibody produced in mouse - SAB1406799 from Sigma-Aldrich Prices $347.00 Sizes 50 µg Host Mouse Clonality Polyclonal

Monoclonal Anti-RAB11B antibody produced in mouse - WH0009230M3 from Sigma-Aldrich Prices $347.00 Sizes 200 µl Host Mouse Clonality Monoclonal Clone 2F1

Anti-RAB11B, C-Terminal antibody produced in rabbit - SAB4503590 from Sigma-Aldrich Prices $335.50 Sizes 100 µg Host Rabbit Clonality Polyclonal

RAB11B antibody - C-terminal region (ARP48246_P050) - ARP48246_P050 from Aviva Systems Biology Prices $289.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Search more