SLC5A11

Gene Symbol SLC5A11
Entrez Gene 115584
Alt Symbol KST1, RKST1, SGLT6, SMIT2
Species Human
Gene Type protein-coding
Description solute carrier family 5 (sodium/inositol cotransporter), member 11
Other Description Na(+)/myo-inositol cotransporter 2|homolog of rabbit KST1|putative sodium-coupled cotransporter RKST1|sodium-dependent glucose cotransporter|sodium/glucose cotransporter KST1|sodium/myo-inositol cotransporter 2|sodium/myo-inositol transporter 2|solute carrier family 5 (sodium/glucose cotransporter), member 11
Swissprots Q6PF02 B7Z329 Q96PP5 Q86Y55 Q6ZUW3 Q05BF1 Q8WWX8
Accessions EAW55781 Q8WWX8 AA772233 AF292385 AAK97053 AJ305237 CAC83728 AK125267 BAC86105 AK295427 BAH12065 AK298373 BAH12770 AK303691 BAH14019 AY044906 AAK97784 BC049385 AAH49385 BC057780 AAH57780 DC332171 U41898 AAB61733 XM_005255080 XP_005255137 XM_005255082 XP_005255139 XM_006721015 XP_006721078 XM_011545723 XP_011544025 XM_011545724 XP_011544026 XM_011545725 XP_011544027 XM_011545726 XP_011544028 XM_011545727 XP_011544029 XM_011545728 XP_011544030 NM_001258411 NP_001245340 NM_001258412 NP_001245341 NM_001258413 NP_001245342 NM_001258414 NP_001245343 NM_052944 NP_443176
Function Involved in the sodium-dependent cotransport of myo- inositol (MI) with a Na(+):MI stoichiometry of 2:1. Exclusively responsible for apical MI transport and absorption in intestine. Also can transport D-chiro-inositol (DCI) but not L-fructose. Exhibits stereospecific cotransport of both D-glucose and D- xylose. May induce apoptosis through the TNF-alpha, PDCD1 pathway. May play a role in the regulation of MI concentration in serum, involving reabsorption in at least the proximal tubule of the kidney. {ECO:0000269|PubMed:15172003}.
Subcellular Location Membrane {ECO:0000250|UniProtKB:Q28728}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q28728}.
Tissue Specificity Highest expression in heart, skeletal muscle, kidney, liver and placenta. Weaker expression in brain, colon, spleen, lung and peripheral blood leukocytes. {ECO:0000269|PubMed:12039040}.

SGLT-6 (H-40) - sc-135408 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

SGLT-6 (P-14) - sc-165476 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

SGLT-6 (S-15) - sc-165477 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

SGLT-6 (D-22) - sc-133997 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Rabbit
Clonality Polyclonal

Anti-SLC5A11 antibody - ab140942 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human liver tissue labelling SLC5A11 with ab140942 at 10 µg/ml.

Anti-SLC5A11 antibody - ab104848 from Abcam

Host Rabbit
Clonality Polyclonal
Anti-SLC5A11 antibody (ab104848) at 1 µg/ml + Jurkat cell lysate at 10 µg

Anti-SLC5A11 antibody - ab61018 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ab61018 at 10µg/ml staining formalin fixed paraffin embedded brain cortex tissue

Anti-SLC5A11 / SMIT2 Antibody (Extracellular Domain) - LS-C122439 from LifeSpan Bioscience

Prices $665.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-SLC5A11 / SMIT2 Antibody (aa226-275) - LS-C80636 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Jurkat cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-SLC5A11 / SMIT2 Antibody - LS-C179229 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC5A11 / SMIT2 Antibody (Extracellular Domain) IHC-plus™ - LS-A2797 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-SLC5A11 antibody LS-A2797 IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-SLC5A11 / SMIT2 Antibody (Internal) IHC-plus™ - LS-A2798 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-SLC5A11 antibody LS-A2798 IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-SLC5A11 / SMIT2 Antibody (N-Terminus) - LS-C16162 from LifeSpan Bioscience

Prices $385.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

SLC5A11 Antibody - NBP1-59635 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SLC5A11 Antibody [NBP1-59635] - Jurkat cell lysate, concentration 0.2-1 ug/ml.

SLC5A11 Antibody - NBP1-82862 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: SLC5A11 Antibody [NBP1-82862] - Staining of human duodenum shows moderate cytoplasmic positivity in glandular cells.

Anti-SLC5A11 antibody produced in rabbit - AV44083 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Cell Type: Jurkat (<B>Cat. No. AV44083</B>).<BR/><B>Lanes</B><BR/>1. Antibody dilution (concentration) 1.0 μg/mL in cell type Jurkat

Anti-SLC5A11 antibody produced in rabbit - HPA035331 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-SLC5A11: <B>Cat. No. HPA035331</B>: Immunohistochemical staining of human duodenum shows moderate cytoplasmic positivity in glandular cells.

SLC5A11 antibody - middle region (ARP44083_P050) - ARP44083_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti -KST1 - K6890-05 from USBiological Life Science

Host Rabbit
Clonality Polyclonal

Anti -KST1 - K6890-06 from USBiological Life Science

Host Rabbit
Clonality Polyclonal

SLC5A11 Antibody (OALA00534) - OALA00534 from Aviva Systems Biology

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

SLC5A11 Antibody (OALA00535) - OALA00535 from Aviva Systems Biology

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

SLC5A11 antibody - 70R-6545 from Fitzgerald

Prices $345.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

SLC5A11 antibody - 70R-20362 from Fitzgerald

Prices $375.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

SLC5A11 / KST1 antibody - 14089-1-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal
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