SLC5A11

Gene Symbol SLC5A11
Entrez Gene 115584
Alt Symbol KST1, RKST1, SGLT6, SMIT2
Species Human
Gene Type protein-coding
Description solute carrier family 5 (sodium/inositol cotransporter), member 11
Other Description Na(+)/myo-inositol cotransporter 2|homolog of rabbit KST1|putative sodium-coupled cotransporter RKST1|sodium-dependent glucose cotransporter|sodium/glucose cotransporter KST1|sodium/myo-inositol cotransporter 2|sodium/myo-inositol transporter 2|solute carrier family 5 (sodium/glucose cotransporter), member 11
Swissprots Q6PF02 B7Z329 Q96PP5 Q86Y55 Q6ZUW3 Q05BF1 Q8WWX8
Accessions EAW55781 Q8WWX8 AA772233 AF292385 AAK97053 AJ305237 CAC83728 AK125267 BAC86105 AK295427 BAH12065 AK298373 BAH12770 AK303691 BAH14019 AY044906 AAK97784 BC049385 AAH49385 BC057780 AAH57780 DC332171 U41898 AAB61733 XM_005255080 XP_005255137 XM_005255082 XP_005255139 XM_006721015 XP_006721078 XM_011545723 XP_011544025 XM_011545724 XP_011544026 XM_011545725 XP_011544027 XM_011545726 XP_011544028 XM_011545727 XP_011544029 XM_011545728 XP_011544030 NM_001258411 NP_001245340 NM_001258412 NP_001245341 NM_001258413 NP_001245342 NM_001258414 NP_001245343 NM_052944 NP_443176
Function Involved in the sodium-dependent cotransport of myo- inositol (MI) with a Na(+):MI stoichiometry of 2:1. Exclusively responsible for apical MI transport and absorption in intestine. Also can transport D-chiro-inositol (DCI) but not L-fructose. Exhibits stereospecific cotransport of both D-glucose and D- xylose. May induce apoptosis through the TNF-alpha, PDCD1 pathway. May play a role in the regulation of MI concentration in serum, involving reabsorption in at least the proximal tubule of the kidney. {ECO:0000269|PubMed:15172003}.
Subcellular Location Membrane {ECO:0000250|UniProtKB:Q28728}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q28728}.
Tissue Specificity Highest expression in heart, skeletal muscle, kidney, liver and placenta. Weaker expression in brain, colon, spleen, lung and peripheral blood leukocytes. {ECO:0000269|PubMed:12039040}.

SGLT-6 CRISPR/Cas9 KO Plasmid (h) - sc-409432 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SGLT-6 HDR Plasmid (h) - sc-409432-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SGLT-6 Double Nickase Plasmid (h) - sc-409432-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SGLT-6 Double Nickase Plasmid (h2) - sc-409432-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SGLT-6 CRISPR Activation Plasmid (h) - sc-409432-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SGLT-6 CRISPR Activation Plasmid (h2) - sc-409432-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SGLT-6 Lentiviral Activation Particles (h) - sc-409432-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SGLT-6 Lentiviral Activation Particles (h2) - sc-409432-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SGLT-6 siRNA (h) - sc-93032 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SGLT-6 shRNA Plasmid (h) - sc-93032-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SGLT-6 shRNA (h) Lentiviral Particles - sc-93032-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SLC5A11 RNAi - H00115584-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN19660 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19660 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

SLC5A11 siRNA (Human) - CRJ4455 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SLC5A11 - MBS8212198 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SLC5A11 (NM_052944.3) - SHH411664 from Creative biogene

Category siRNA
Species Reactivities Human

Human SLC5A11 siRNA - orb274956 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SLC5A11 shRNA Plasmid (Human) - CHJ4455 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SLC5A11 miRNA 3'UTR clone - MiUTR3H-11104 from Creative biogene

Species Reactivities Human
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