PACS2

Gene Symbol PACS2
Entrez Gene 23241
Alt Symbol PACS-2, PACS1L
Species Human
Gene Type protein-coding
Description phosphofurin acidic cluster sorting protein 2
Other Description PACS1-like protein
Swissprots Q96FL7 A2VDJ9 Q6P191 O60342 G8JLK3 Q86VP3
Accessions EAW81915 Q86VP3 AB011174 BAA25528 AB029326 BAB87116 AB072449 BAB88325 AK098354 BAC05290 AL539052 AY320284 AAQ83882 BC010663 AAH10663 BC028418 BC050351 AAH50351 BC065220 AAH65220 BC095493 BC131591 AAI31592 BU944012 CA423467 DA177001 DA275449 DA408379 DA491365 HY009105 XM_005267462 XP_005267519 XM_005267463 XP_005267520 XM_006720085 XP_006720148 XM_006720086 XP_006720149 XM_006720087 XP_006720150 XM_006720088 XP_006720151 XM_006720089 XP_006720152 XM_006720090 XP_006720153 XM_006720091 XP_006720154 XM_006720092 XP_006720155 XM_011536585 XP_011534887 NM_001100913 NP_001094383 NM_001243127 NP_001230056 NM_015197 NP_056012
Function Multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria communication, including the apposition of mitochondria with the ER and ER homeostasis. In addition, in response to apoptic inducer, translocates BIB to mitochondria, which initiates a sequence of events including the formation of mitochondrial truncated BID, the release of cytochrome c, the activation of caspase-3 thereby causing cell death. May also be involved in ion channel trafficking, directing acidic cluster-containing ion channels to distinct subcellular compartments. {ECO:0000269|PubMed:15692563, ECO:0000269|PubMed:15692567}.
Subcellular Location Endoplasmic reticulum lumen {ECO:0000269|PubMed:15692567}. Mitochondrion {ECO:0000269|PubMed:15692567}.
Tissue Specificity Broadly expressed, with greatest levels in skeletal muscle followed by heart, brain, pancreas and testis. {ECO:0000269|PubMed:15692567}.

PACS-2 (Q-20) - sc-160645 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PACS-2 (Q-20): sc-160645. Western blot analysis of PACS-2 expression in mouse skeletal muscle tissue extract.

PACS-2 (E-17) - sc-160643 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PACS-2 (E-17): sc-160643. Western blot analysis of PACS-2 expression in A549 (A), K-562 (B) and Hep G2 (C) whole cell lysates.

Anti-PACS2 antibody - ab129402 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-PACS2 antibody (ab129402) at 1/100 dilution + HL-60 cell line lysate at 35 µg

Anti-PACS2 antibody - ab121136 from Abcam

Prices $443.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical staining of paraffin embedded human liver tissue with anti-PACS2 antibody (ab121136; dilution 1:50) showing strong cytoplasmic positivity in hepatocytes.

Anti-PACS2 Antibody (aa641-671, AP) - LS-C265441 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PACS2 Antibody (aa641-671, Biotin) - LS-C265442 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PACS2 Antibody (aa641-671, APC) - LS-C265443 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PACS2 Antibody (aa641-671, FITC) - LS-C265444 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PACS2 Antibody (aa641-671, PE) - LS-C265445 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PACS2 Antibody (aa641-671, Azide-free, HRP) - LS-C265446 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PACS2 Antibody (Internal) IHC-plus™ - LS-B12223 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)

Anti-PACS2 Antibody (aa642-671) - LS-C163335 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
PACS2 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human skeletal muscle followed by peroxidase-conjugated secondary antibody and DAB staining.

PACS2 Antibody - NBP1-81496 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PACS2 antibody produced in rabbit - SAB2105784 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-PACS2: <B>Cat. No. SAB2105784</B>: PACS2 in A549 cell lysates with PACS2 antibody at 1.0 μg/mL.

Anti-PACS2 antibody produced in rabbit - HPA001423 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-PACS2: <B>Cat. No. HPA001423</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human liver tissue showing cytoplasmic and/or membranous staining of hepatocytes.

PACS2 antibody - middle region (ARP51659_P050) - ARP51659_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PACS2-Antibody-C-term - AP13142b from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
PACS2 Antibody (C-term) (Cat. #AP13142b) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the PACS2 antibody detected the PACS2 protein (arrow).

PACS2 antibody - GTX110869 from GeneTex

Prices $119.00
Sizes 25 μl
Host Rabbit
Clonality Polyclonal

PACS2 Antibody - C-terminal region (OAAB09441) - OAAB09441 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

Phosphofurin Acidic Cluster Sorting Protein 2 Antibody - abx114462 from Abbexa

Host Rabbit
Clonality Polyclonal

PACS2 antibody - 19508-1-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal
Immunofluorescent analysis of MCF-7 cells using 19508-1-AP( PACS2-Specific Antibody) at dilution of 1:25 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

PACS2 Antibody - 8189 from ProSci

Prices $79.00, $325.00
Sizes 20 µg, 100 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of PACS2 in mouse brain tissue lysate with PACS2 antibody at 1 μg/ml.

PACS2-Specific antibody - 19508-1-AP from Proteintech Group

Prices $279.00
Sizes con: 47 μg/150μl
Host Rabbit
Clonality Polyclonal
mouse brain tissue were subjected to SDS PAGE followed by western blot with 19508-1-AP(PACS2-Specific antibody) at dilution of 1:600

PACS2, Polyclonal Antibody - MBS153374 from MyBioSource

Prices $140.00, $355.00
Sizes 20 µg, 100 µg
Host Rabbit
Clonality Polyclonal

PACS2 Antibody - GWB-MS262A from Genway Biotech

Prices $404.00
Sizes 50 µg
Clonality Polyclonal
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