PACS2

Gene Symbol	PACS2
Entrez Gene	23241
Alt Symbol	PACS-2, PACS1L
Species	Human
Gene Type	protein-coding
Description	phosphofurin acidic cluster sorting protein 2
Other Description	PACS1-like protein
Swissprots	Q96FL7 A2VDJ9 Q6P191 O60342 G8JLK3 Q86VP3
Accessions	EAW81915 Q86VP3 AB011174 BAA25528 AB029326 BAB87116 AB072449 BAB88325 AK098354 BAC05290 AL539052 AY320284 AAQ83882 BC010663 AAH10663 BC028418 BC050351 AAH50351 BC065220 AAH65220 BC095493 BC131591 AAI31592 BU944012 CA423467 DA177001 DA275449 DA408379 DA491365 HY009105 XM_005267462 XP_005267519 XM_005267463 XP_005267520 XM_006720085 XP_006720148 XM_006720086 XP_006720149 XM_006720087 XP_006720150 XM_006720088 XP_006720151 XM_006720089 XP_006720152 XM_006720090 XP_006720153 XM_006720091 XP_006720154 XM_006720092 XP_006720155 XM_011536585 XP_011534887 NM_001100913 NP_001094383 NM_001243127 NP_001230056 NM_015197 NP_056012
Function	Multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria communication, including the apposition of mitochondria with the ER and ER homeostasis. In addition, in response to apoptic inducer, translocates BIB to mitochondria, which initiates a sequence of events including the formation of mitochondrial truncated BID, the release of cytochrome c, the activation of caspase-3 thereby causing cell death. May also be involved in ion channel trafficking, directing acidic cluster-containing ion channels to distinct subcellular compartments. {ECO:0000269|PubMed:15692563, ECO:0000269|PubMed:15692567}.
Subcellular Location	Endoplasmic reticulum lumen {ECO:0000269|PubMed:15692567}. Mitochondrion {ECO:0000269|PubMed:15692567}.
Tissue Specificity	Broadly expressed, with greatest levels in skeletal muscle followed by heart, brain, pancreas and testis. {ECO:0000269|PubMed:15692567}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human PACS2 full length protein - ab161579 from Abcam Category Protein Source Wheat germ Species Human

PACS2 Antibody Blocking Peptide - LS-E2219 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human PACS2 Protein - H00023241-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

PACS2-Antibody-C-term-Blocking-Peptide - BP13142b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

PACS2 - H00023241-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

PACS2 - H00023241-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

PACS2 Peptide - 8189P from ProSci Category Peptide Species Human

Recombinant Human Phosphofurin acidic cluster sorting protein 2(PACS2) ,partial - CSB-YP017372HU CSB-EP017372HU CSB-BP017372HU CSB-MP017372HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

PACS2 (transcript variant 1) - TP318762 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Phosphofurin acidic cluster sorting protein 2 (PACS2), partial, Recombinant Protein - MBS1380846 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

PACS2 Recombinant Protein Antigen - NBP1-81496PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

PACS2 Peptide, Human - M34GP11233H from Creative Peptides Category Peptide Source Synthetic. Species Human

PACS2 Recombinant Protein Antigen - NBP2-58824PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Recombinant Human PACS2 Protein, MYC/DDK-tagged - PACS2-206H from Creative Biomart Category Protein Source HEK293 Species Human

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