Dkk3

Gene Symbol Dkk3
Entrez Gene 50781
Alt Symbol AW061014, C87148
Species Mouse
Gene Type protein-coding
Description dickkopf homolog 3 (Xenopus laevis)
Other Description dickkopf-3|dickkopf-related protein 3|dkk-3|mDkk-3
Swissprots Q9QUN9
Accessions EDL17021 EDL17022 EDL17023 EDL17024 Q9QUN9 AF177400 AAF02680 AJ243964 CAB60111 AK004853 BAB23617 AK013054 AK013622 AK191518 AK192759 AK199048 AK207247 AK208577 AK209927 BC005519 BC046304 AAH46304 BC050934 AAH50934 XM_006508013 XP_006508076 XM_006508014 XP_006508077 NM_015814 NP_056629
Function Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero- posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity). {ECO:0000250}.
Subcellular Location Secreted.
Tissue Specificity Highest expression in brain, eye and heart.

Dkk-3 CRISPR/Cas9 KO Plasmid (m) - sc-424494 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Dkk-3 HDR Plasmid (m) - sc-424494-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Dkk-3 Double Nickase Plasmid (m) - sc-424494-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Dkk-3 Double Nickase Plasmid (m2) - sc-424494-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Dkk-3 CRISPR Activation Plasmid (m) - sc-424494-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Dkk-3 CRISPR Activation Plasmid (m2) - sc-424494-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Dkk-3 Lentiviral Activation Particles (m) - sc-424494-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Dkk-3 Lentiviral Activation Particles (m2) - sc-424494-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Dkk-3 siRNA (m) - sc-41103 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

Dkk-3 shRNA Plasmid (m) - sc-41103-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

Dkk-3 shRNA (m) Lentiviral Particles - sc-41103-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

MISSION® esiRNA - EMU012251 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN30017 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND30017 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

DKK3 siRNA (Mouse) - CRM5147 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

DKK3 - MBS8214047 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

shRNA set against Mouse DKK3 (NM_015814.2) - SHH278369 from Creative biogene

Category siRNA
Species Reactivities Mouse

shRNA set against Mouse Dkk3(NM_015814.2) - SHH006203 from Creative biogene

Category siRNA
Species Reactivities Mouse

Mouse DKK3 siRNA - orb284623 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

DKK3 shRNA Plasmid (Mouse) - CHM5147 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Mouse
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