IGSF8

Gene Symbol IGSF8
Entrez Gene 93185
Alt Symbol CD316, CD81P3, EWI-2, EWI2, KCT-4, LIR-D1, PGRL
Species Human
Gene Type protein-coding
Description immunoglobulin superfamily, member 8
Other Description CD81 partner 3|glu-Trp-Ile EWI motif-containing protein 2|immunoglobulin superfamily member 8|keratinocytes-associated transmembrane protein 4|prostaglandin regulatory-like protein
Swissprots Q969P0 Q9BTG9 Q8NG09 Q96DP4
Accessions EAW52743 EAW52744 EAW52745 EAW52746 Q969P0 AF311906 AAM94901 AF407274 AAL01052 AK055843 BAB71027 AK090396 BAC03377 AK308115 AY044845 AAK92220 AY157579 AAO13163 BC004108 AAH04108 BC011896 AAH11896 BC023649 AAH23649 BC053881 AAH53881 BU172537 DB501388 XM_005245614 XP_005245671 XM_006711631 XP_006711694 XM_011510159 XP_011508461 NM_001206665 NP_001193594 NM_052868 NP_443100
Function May play a key role in diverse functions ascribed to CD81 and CD9 such as oocytes fertilization or hepatitis C virus function. May regulate proliferation and differentiation of keratinocytes. May be a negative regulator of cell motility: suppresses T-cell mobility coordinately with CD81, associates with CD82 to suppress prostate cancer cell migration, regulates epidermoid cell reaggregation and motility on laminin-5 with CD9 and CD81 as key linkers. May also play a role on integrin- dependent morphology and motility functions. May participate in the regulation of neurite outgrowth and maintenance of the neural network in the adult brain. {ECO:0000269|PubMed:11504738, ECO:0000269|PubMed:12750295, ECO:0000269|PubMed:12752121, ECO:0000269|PubMed:14662754, ECO:0000269|PubMed:15070678}.
Subcellular Location Cell membrane {ECO:0000250}; Single-pass membrane protein.
Tissue Specificity Expressed in brain, kidney, testis, liver and placenta with moderate expression in all other tissues. Detected on a majority of B-cells, T-cells, and natural killer cells but not on monocytes, polynuclear cells and platelets. {ECO:0000269|PubMed:11504738, ECO:0000269|PubMed:12708969, ECO:0000269|PubMed:12750295}.

Immunoglobulin superfamily member 8 (IGSF8), Human, ELISA Kit - CSB-EL011565HU from ARP American Research Products

Category ELISA Kit
Prices $495.00, $695.00, $696.00, $699.00
Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

immunoglobulin superfamily, member 8, ELISA Kit - MBS911793 from MyBioSource

Category ELISA Kit
Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00
Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity The minimum detectable dose of human IGSF8 is typically less than 0.039 ng/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations.
Range 0.156 ng/ml -10 ng/ml.

Human Immunoglobulin superfamily member 8(IGSF8) ELISA kit - CSB-EL011565HU from Cusabio

Category ELISA Kit
Sensitivity 0.039 ng/ml
Range 0.156 ng/ml-10 ng/ml

Human Immunoglobulin superfamily member 8 (IGSF8) ELISA Kit - EKC34117 from Biomatik

Category ELISA Kit
Prices $705.00, $2,820.00, $5,288.00
Sizes 96 t, 5x96t, 10x96t
Sensitivity 0.039 ng/ml
Range 0.156 ng/ml-10 ng/ml

Human IGSF8 ELISA Kit - E019653 from Biobool

Category ELISA Kit
Sensitivity The minimum detectable dose of human IGSF8 is typically less than 0.039 ng/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the m

IGSF8 ELISA Kit (Human) (OKCA01306) - OKCA01306 from Aviva Systems Biology

Category ELISA Kit
Prices $600.00
Sizes 96 wells
Sensitivity 0.039 ng/mL
Range 0.156 - 10 ng/mL

Human IGSF8 ELISA Kit - orb404601 from Biorbyt

Category ELISA Kit
Sensitivity 0.039 ng/ml
Range 0.156 ng/ml-10 ng/ml
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