IGSF8

Gene Symbol IGSF8
Entrez Gene 93185
Alt Symbol CD316, CD81P3, EWI-2, EWI2, KCT-4, LIR-D1, PGRL
Species Human
Gene Type protein-coding
Description immunoglobulin superfamily, member 8
Other Description CD81 partner 3|glu-Trp-Ile EWI motif-containing protein 2|immunoglobulin superfamily member 8|keratinocytes-associated transmembrane protein 4|prostaglandin regulatory-like protein
Swissprots Q969P0 Q9BTG9 Q8NG09 Q96DP4
Accessions EAW52743 EAW52744 EAW52745 EAW52746 Q969P0 AF311906 AAM94901 AF407274 AAL01052 AK055843 BAB71027 AK090396 BAC03377 AK308115 AY044845 AAK92220 AY157579 AAO13163 BC004108 AAH04108 BC011896 AAH11896 BC023649 AAH23649 BC053881 AAH53881 BU172537 DB501388 XM_005245614 XP_005245671 XM_006711631 XP_006711694 XM_011510159 XP_011508461 NM_001206665 NP_001193594 NM_052868 NP_443100
Function May play a key role in diverse functions ascribed to CD81 and CD9 such as oocytes fertilization or hepatitis C virus function. May regulate proliferation and differentiation of keratinocytes. May be a negative regulator of cell motility: suppresses T-cell mobility coordinately with CD81, associates with CD82 to suppress prostate cancer cell migration, regulates epidermoid cell reaggregation and motility on laminin-5 with CD9 and CD81 as key linkers. May also play a role on integrin- dependent morphology and motility functions. May participate in the regulation of neurite outgrowth and maintenance of the neural network in the adult brain. {ECO:0000269|PubMed:11504738, ECO:0000269|PubMed:12750295, ECO:0000269|PubMed:12752121, ECO:0000269|PubMed:14662754, ECO:0000269|PubMed:15070678}.
Subcellular Location Cell membrane {ECO:0000250}; Single-pass membrane protein.
Tissue Specificity Expressed in brain, kidney, testis, liver and placenta with moderate expression in all other tissues. Detected on a majority of B-cells, T-cells, and natural killer cells but not on monocytes, polynuclear cells and platelets. {ECO:0000269|PubMed:11504738, ECO:0000269|PubMed:12708969, ECO:0000269|PubMed:12750295}.

IGSF8 (D-15) - sc-103561 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
IGSF8 (D-15): sc-103561. Western blot analysis of IGSF8 expression in non-transfected: sc-117752 (A) and mouse IGSF8 transfected: sc-121018 (B) 293T whole cell lysates.

IGSF8 (P-13) - sc-103562 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

IGSF8 (S-15) - sc-103563 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-IGSF8 antibody - ab170625 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-IGSF8 antibody (ab170625) at 1/100 dilution + Mouse cerebellum tissue lysates at 35 µg

Anti-IGSF8 antibody - ab74890 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-IGSF8 antibody (ab74890) at 1 µg/ml + Brain (Human) Tissue Lysate - adult normal tissue (ab29466) at 10 µgSecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutionPerformed under reducing conditions.

Anti-IGSF8 antibody - ab194549 from Abcam

Prices $370.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Anti-IGSF8 antibody (ab194549) at 1/500 dilution + Raw 264.7 cell lysate at 50 µg

Anti-IGSF8 antibody - ab133390 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of Formalin-fixed, Paraffin-embedded Human brain (putamen) tissue labelling IGSF8 with ab133390 at 20 µg/ml, followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-CD316 / IGSF8 Antibody (aa226-254, AP) - LS-C236534 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CD316 / IGSF8 Antibody (aa226-254, Biotin) - LS-C236535 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CD316 / IGSF8 Antibody (aa226-254, APC) - LS-C236536 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CD316 / IGSF8 Antibody (aa226-254, PE) - LS-C236541 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CD316 / IGSF8 Antibody (aa226-254, FITC) - LS-C236537 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CD316 / IGSF8 Antibody (aa226-254, Azide-free, HRP) - LS-C249257 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CD316 / IGSF8 Antibody (aa220-323) - LS-C306825 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-CD316 / IGSF8 Antibody (aa233-262) - LS-C322181 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CD316 / IGSF8 Antibody (aa226-254) - LS-C165162 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
IGSF8 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human kidney tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-CD316 / IGSF8 Antibody (Internal) IHC-plus™ - LS-A9934 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-IGSF8 antibody LS-A9934 IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-CD316 / IGSF8 Antibody (Internal) IHC-plus™ - LS-A9272 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-IGSF8 antibody LS-A9272 IHC of human brain, putamen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IGSF8/CD316 Antibody - NBP1-68899 from Novus Biologicals

Prices $139.00
Sizes 20 µl
Host Rabbit
Clonality Polyclonal
Western Blot: IGSF8 Antibody [NBP1-68899] - Titration: 0.2-1 ug/ml, Positive Control: 721_B cell lysate.

IGSF8/CD316 Antibody - NBP1-85761 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

IGSF8/CD316 Antibody - H00093185-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: IGSF8/CD316 Antibody [H00093185-A01] - IGSF8 polyclonal antibody (A01), Lot # ABNOVA060707QCS1 Western Blot analysis of IGSF8 expression in K-562 ( Cat # L009V1 ).

IGSF8/CD316 Antibody (1E4) - H00093185-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1E4
Sandwich ELISA: IGSF8/CD316 Antibody (1E4) [H00093185-M01] - Detection limit for recombinant GST tagged IGSF8 is approximately 0.1ng/ml as a capture antibody.

Monoclonal Anti-IGSF8 antibody produced in mouse - WH0093185M1 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1E4
<B>Sandwich ELISA</B><BR/>Monoclonal Anti-IGSF8, <B>Cat. No. WH0093185M1</B>: the detection limit for recombinant GST tagged IGSF8 is approximately 0.1ng/mL.

Anti-IGSF8 antibody produced in rabbit - SAB2900687 from Sigma-Aldrich

Prices $465.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-IGSF8 (Internal), antibody produced in rabbit: <B>Cat. No. SAB2900687</B>: Anti-IGSF8 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

ANTI-IGSF8 (CENTER) antibody produced in rabbit - SAB1307022 from Sigma-Aldrich

Prices $326.00
Sizes 40 tst
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-IGSF8 (Center): <B>Cat. No. SAB1307022</B>: IGSF8 Antibody (Center) western blot analysis in Mouse cerebellum tissue lysates (35 μg/lane).
Search more