Gene Symbol | HENMT1 |
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Entrez Gene | 113802 |
Alt Symbol | C1orf59, HEN1 |
Species | Human |
Gene Type | protein-coding |
Description | HEN1 methyltransferase homolog 1 (Arabidopsis) |
Other Description | small RNA 2'-O-methyltransferase |
Swissprots | A8MRR6 Q96NN0 B1AM17 Q5T8I9 Q96EJ7 B1AM16 |
Accessions | EAW56324 EAW56325 EAW56326 Q5T8I9 AK055087 BAB70852 AK310152 AK311542 BC012198 AAH12198 BC088366 AAH88366 BP378034 DB510959 HQ448278 ADQ32758 XM_005270411 XP_005270468 XM_011540567 XP_011538869 XM_011540568 XP_011538870 NM_001102592 NP_001096062 NM_144584 NP_653185 |
Function | Methyltransferase that adds a 2'-O-methyl group at the 3'-end of piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. This probably protects the 3'-end of piRNAs from uridylation activity and subsequent degradation. Stabilization of piRNAs is essential for gametogenesis (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Note=Component of the meiotic nuage, also named P granule, a germ-cell-specific organelle required to repress transposon activity during meiosis. {ECO:0000250}. |
C1orf59 (E-16) - sc-163886 from Santa Cruz Biotechnology
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C1orf59 (H-60) - sc-368708 from Santa Cruz Biotechnology
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Anti-HENMT1 antibody - ab121991 from Abcam
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Anti-HENMT1 antibody - C-terminal - ab178036 from Abcam
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Anti-HENMT1 Antibody (aa21-70) - LS-C205499 from LifeSpan Bioscience
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Anti-HENMT1 Antibody (aa278-327) - LS-C205498 from LifeSpan Bioscience
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HENMT1 Antibody - NBP1-32620 from Novus Biologicals
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HENMT1 Antibody - NBP1-88330 from Novus Biologicals
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HENMT1 Polyclonal Antibody - bs-15454R from Bioss
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Anti-HENMT1 antibody produced in rabbit - HPA028495 from Sigma-Aldrich
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HENMT1 Antibody - C-terminal region (ARP70536_P050) - ARP70536_P050 from Aviva Systems Biology
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HENMT1 Antibody - N-terminal region (ARP70537_P050) - ARP70537_P050 from Aviva Systems Biology
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HENMT1 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-15454R-A350 from Bioss
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HENMT1 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-15454R-A488 from Bioss
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HENMT1 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-15454R-A555 from Bioss
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HENMT1 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-15454R-A647 from Bioss
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HENMT1 Polyclonal Antibody, Cy3 Conjugated - bs-15454R-Cy3 from Bioss
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HENMT1 Polyclonal Antibody, Cy5 Conjugated - bs-15454R-Cy5 from Bioss
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HENMT1 Polyclonal Antibody, Cy5.5 Conjugated - bs-15454R-Cy5.5 from Bioss
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HENMT1 Polyclonal Antibody, Cy7 Conjugated - bs-15454R-Cy7 from Bioss
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HENMT1 Polyclonal Antibody, FITC Conjugated - bs-15454R-FITC from Bioss
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HENMT1 Polyclonal Antibody, Biotin Conjugated - bs-15454R-Biotin from Bioss
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HENMT1 Polyclonal Antibody, HRP Conjugated - bs-15454R-HRP from Bioss
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LOC113802 - MBS275528 from MyBioSource
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Anti-HENMT1 (aa 278-327) polyclonal antibody - DPABH-12672 from Creative Diagnostics
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