Abca7

Gene Symbol Abca7
Entrez Gene 27403
Alt Symbol ABCX, Abc51
Species Mouse
Gene Type protein-coding
Description ATP-binding cassette, sub-family A (ABC1), member 7
Other Description ATP-binding cassette sub-family A member 7
Swissprots Q9JL36 Q91V24
Accessions AAK56863 EDL31613 Q91V24 AF213395 AAF31434 AF287141 AAK56862 AK143653 AK178671 AK194023 AK195405 BC024511 AAH24511 BC036566 BC038521 BC145120 AAI45121 BC150708 AAI50709 XM_006513710 XP_006513773 XM_006513711 XP_006513774 XM_006513712 XP_006513775 XM_006513713 XP_006513776 XM_006513714 XP_006513777 XR_380402 XR_380403 NM_013850 NP_038878
Function Plays a role in phagocytosis by macrophages of apoptotic cells. Binds APOA1 and may function in apolipoprotein-mediated phospholipid efflux from cells. May also mediate cholesterol efflux. May regulate cellular ceramide homeostasis during keratinocytes differentiation. {ECO:0000269|PubMed:12917409, ECO:0000269|PubMed:15550377, ECO:0000269|PubMed:16908670}.
Subcellular Location Cell membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. Note=Localizes to cell membrane ruffles and phagocytic cups of macrophages stimulated with C1q or apoptotic cells. Localizes to the cytoplasm of resting macrophages, probably in Golgi and endosomes. Localizes to the apical brush border of cells in the proximal tubules of kidney.
Tissue Specificity Widely expressed with higher expression in brain, lung, adrenal gland and spleen (at protein level). Highly expressed in spleen and hematopoietic tissues. {ECO:0000269|PubMed:11435699, ECO:0000269|PubMed:12917409, ECO:0000269|PubMed:15550377}.
Top Pathways ABC transporters

ABCA7 (M-70) - sc-50525 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
ABCA7 (M-70): sc-50525. Western blot analysis of ABCA7 expression in human PBL whole cell lysate.

ABCA7 (7A1-144) - sc-130576 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rat
Clonality Monoclonal

Anti-ABCA7 antibody - ab110718 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-ABCA7 antibody (ab110718) at 1 µg/ml + Mouse liver lysate at 10 µg

ABCA7 Antibody (7A1-144) - NB400-166 from Novus Biologicals

Prices $299.00
Sizes 100 µl
Host Rat
Clonality Monoclonal
Clone 7A1-144
Western Blot: ABCA7 Antibody (7A1-144) [NB400-166] - Detection of ABCA7 using NB 400-166 at various dilutions in ABCA7 transfected HeLa cell lysates.

ABCA7 Antibody (7A1-144) - NB400-163 from Novus Biologicals

Prices $99.00, $299.00
Sizes 25 µl, 100 µl
Host Rat
Clonality Monoclonal
Clone 7A1-144
Western Blot: ABCA7 Antibody (7A1-144) [NB400-163] - Total protein from mouse platelets was separated on a 7.5% gel by SDS-PAGE, transferred to PVDF membrane and blocked in 5% non-fat milk in TBST. The membrane was probed with 0.5 ug/ml anti-ABCA7 in 5% non-fat milk in TBST and detected with an anti-rat HRP secondary antibody using chemiluminescence.

ABCA7 Antibody - NBP1-69064 from Novus Biologicals

Prices $349.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western Blot: ABCA7 Antibody [NBP1-69064] - Titration: 0.2-1 ug/ml, Positive Control: Mouse Liver.

ABCA7 Antibody (7A1-144) [DyLight 550] - NB400-163R from Novus Biologicals

Prices $319.00
Sizes 100 µl
Host Rat
Clonality Monoclonal
Clone 7A1-144

ABCA7 Antibody (7A1-144) [DyLight 488] - NB400-163G from Novus Biologicals

Prices $319.00
Sizes 100 µl
Host Rat
Clonality Monoclonal
Clone 7A1-144

ABCA7 Antibody (7A1-144) [DyLight 650] - NB400-163C from Novus Biologicals

Prices $319.00
Sizes 100 µl
Host Rat
Clonality Monoclonal
Clone 7A1-144

ABCA7 Antibody (7A1-144) [HRP] - NB400-163H from Novus Biologicals

Prices $309.00
Sizes 100 µl
Host Rat
Clonality Monoclonal
Clone 7A1-144

ABCA7 Antibody (7A1-144) [Biotin] - NB400-163B from Novus Biologicals

Prices $299.00
Sizes 100 µl
Host Rat
Clonality Monoclonal
Clone 7A1-144

ABCA7 Antibody (7A1-144) [Allophycocyanin] - NB400-163APC from Novus Biologicals

Prices $329.00
Sizes 100 tests
Host Rat
Clonality Monoclonal
Clone 7A1-144

ABCA7 Antibody (7A1-144) [DyLight 350] - NB400-163UV from Novus Biologicals

Prices $319.00
Sizes 100 tests
Host Rat
Clonality Monoclonal
Clone 7A1-144

ABCA7 Antibody (7A1-144) [DyLight 405] - NB400-163V from Novus Biologicals

Prices $319.00
Sizes 100 µl
Host Rat
Clonality Monoclonal
Clone 7A1-144

ABCA7 Antibody (7A1-144) [FITC] - NB400-163F from Novus Biologicals

Prices $299.00
Sizes 100 µl
Host Rat
Clonality Monoclonal
Clone 7A1-144

ABCA7 Antibody (7A1-144) [PerCP] - NB400-163PCP from Novus Biologicals

Prices $329.00
Sizes 100 tests
Host Rat
Clonality Monoclonal
Clone 7A1-144

ABCA7 Antibody (7A1-144) [Alexa Fluor (R) 700] - NB400-163AF700 from Novus Biologicals

Prices $319.00
Sizes 100 tests
Host Rat
Clonality Monoclonal
Clone 7A1-144

ABCA7 Antibody (7A1-144) [Alexa Fluor (R) 647] - NB400-163AF647 from Novus Biologicals

Prices $319.00
Sizes 100 tests
Host Rat
Clonality Monoclonal
Clone 7A1-144

ABCA7 Antibody (7A1-144) [Alexa Fluor (R) 488] - NB400-163AF488 from Novus Biologicals

Prices $329.00
Sizes 100 tests
Host Rat
Clonality Monoclonal
Clone 7A1-144

ABCA7 Antibody (7A1-144) [Alexa Fluor (R) 405] - NB400-163AF405 from Novus Biologicals

Prices $319.00
Sizes 100 tests
Host Rat
Clonality Monoclonal
Clone 7A1-144

ABCA7 Antibody (7A1-144) [7C] - NB400-163V2 from Novus Biologicals

Prices $319.00
Sizes 100 tests
Host Rat
Clonality Monoclonal
Clone 7A1-144

ABCA7 Antibody (7A1-144) [DyLight 405LS] - NB400-163V3 from Novus Biologicals

Prices $319.00
Sizes 100 tests
Host Rat
Clonality Monoclonal
Clone 7A1-144

ABCA7 Antibody (7A1-144) [DyLight 680] - NB400-163FR from Novus Biologicals

Prices $319.00
Sizes 100 tests
Host Rat
Clonality Monoclonal
Clone 7A1-144

ABCA7 Antibody (7A1-144) [DyLight 755] - NB400-163IR from Novus Biologicals

Prices $319.00
Sizes 100 tests
Host Rat
Clonality Monoclonal
Clone 7A1-144

ABCA7 Antibody (7A1-144) [PE] - NB400-163PE from Novus Biologicals

Host Rat
Clonality Monoclonal
Clone 7A1-144
Search more