| Gene Symbol |
RFNG
|
| Entrez Gene |
5986
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
|
| Other Description |
O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase|beta-1,3-N-acetylglucosaminyltransferase radical fringe|radical fringe homolog
|
| Swissprots |
Q9Y644 O00588
|
| Accessions |
AAD34321 EAW89735 EAW89736 EAW89737 EAW89738 EAW89739 EAW89740 Q9Y644 AF038196 AK094016 BAC04269 AK293568 BAG57039 AK302068 BAG63458 BC014495 BC035781 BC050399 BC069034 BC080181 BC146805 AAI46806 BF435018 U94353 AAC51359 XM_011523587 XP_011521889 NM_002917 NP_002908
|
| Function |
Glycosyltransferase that initiates the elongation of O- linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. May be involved in limb formation and in neurogenesis (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
|
| Top Pathways |
Other types of O-glycan biosynthesis, Notch signaling pathway
|
![Western Blot: Radical Fringe Overexpression Lysate (Adult Normal) [NBP2-10855] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Radical Fringe.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/25060_Radical%2520Fringe%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBP2-10855-img0001.jpg)