Gene Symbol | RFNG |
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Entrez Gene | 5986 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
Other Description | O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase|beta-1,3-N-acetylglucosaminyltransferase radical fringe|radical fringe homolog |
Swissprots | Q9Y644 O00588 |
Accessions | AAD34321 EAW89735 EAW89736 EAW89737 EAW89738 EAW89739 EAW89740 Q9Y644 AF038196 AK094016 BAC04269 AK293568 BAG57039 AK302068 BAG63458 BC014495 BC035781 BC050399 BC069034 BC080181 BC146805 AAI46806 BF435018 U94353 AAC51359 XM_011523587 XP_011521889 NM_002917 NP_002908 |
Function | Glycosyltransferase that initiates the elongation of O- linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. May be involved in limb formation and in neurogenesis (By similarity). {ECO:0000250}. |
Subcellular Location | Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}. |
Top Pathways | Other types of O-glycan biosynthesis, Notch signaling pathway |
Radical Fringe CRISPR/Cas9 KO Plasmid (h) - sc-410977 from Santa Cruz Biotechnology
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Radical Fringe HDR Plasmid (h) - sc-410977-HDR from Santa Cruz Biotechnology
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Radical Fringe Double Nickase Plasmid (h) - sc-410977-NIC from Santa Cruz Biotechnology
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Radical Fringe Double Nickase Plasmid (h2) - sc-410977-NIC-2 from Santa Cruz Biotechnology
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Radical Fringe CRISPR Activation Plasmid (h) - sc-410977-ACT from Santa Cruz Biotechnology
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Radical Fringe CRISPR Activation Plasmid (h2) - sc-410977-ACT-2 from Santa Cruz Biotechnology
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Radical Fringe Lentiviral Activation Particles (h) - sc-410977-LAC from Santa Cruz Biotechnology
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Radical Fringe Lentiviral Activation Particles (h2) - sc-410977-LAC-2 from Santa Cruz Biotechnology
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Radical Fringe siRNA (h) - sc-39494 from Santa Cruz Biotechnology
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Radical Fringe shRNA Plasmid (h) - sc-39494-SH from Santa Cruz Biotechnology
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Radical Fringe shRNA (h) Lentiviral Particles - sc-39494-V from Santa Cruz Biotechnology
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RFNG RNAi - H00005986-R02 from Novus Biologicals
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RFNG RNAi - H00005986-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN18172 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18172 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR12322 from Sigma-Aldrich
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RFNG siRNA (Human) - CRH4054 from Cohesion Biosciences
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RFNG - MBS8223195 from MyBioSource
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shRNA set against Human RFNG (NM_002917.1) - SHH392276 from Creative biogene
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shRNA set against Human RFNG(NM_002917.1) - SHR177396 from Creative biogene
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Human RFNG siRNA - orb264556 from Biorbyt
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RFNG shRNA Plasmid (Human) - CHH4054 from Cohesion Biosciences
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RFNG miRNA 3'UTR clone - MiUTR1H-08755 from Creative biogene
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