Gene Symbol | HNRNPU |
---|---|
Entrez Gene | 3192 |
Alt Symbol | HNRPU, SAF-A, SAFA, U21.1, hnRNP U |
Species | Human |
Gene Type | protein-coding |
Description | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) |
Other Description | heterogeneous nuclear ribonucleoprotein U|p120 nuclear protein|pp120|scaffold attachment factor A |
Swissprots | Q8N174 Q00839 Q9BQ09 O75507 Q96HY9 |
Accessions | EAW77126 EAW77127 Q00839 AF068846 AAC19382 AF461014 AAP97707 AK095525 AK126868 BAG54384 AK130669 AK297119 BAG59625 AK307661 BC003367 AAH03367 BC003621 AAH03621 BC007950 AAH07950 BC015782 AAH15782 BC024767 AAH24767 BC034925 AAH34925 DQ893316 ABM84242 DQ896631 ABM87630 EU831468 ACE87155 EU831555 ACE86474 X65488 CAA46472 NM_004501 NP_004492 NM_031844 NP_114032 |
Function | Component of the CRD-mediated complex that promotes MYC mRNA stabilization. Binds to pre-mRNA. Has high affinity for scaffold-attached region (SAR) DNA. Binds to double- and single- stranded DNA and RNA. Plays a role in the circadian regulation of the core clock component ARNTL/BMAL1 transcription (By similarity). {ECO:0000250|UniProtKB:Q8VEK3, ECO:0000269|PubMed:19029303}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:20858735}. Cytoplasm {ECO:0000269|PubMed:19029303}. Cell surface {ECO:0000269|PubMed:7993898}. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Component of ribonucleosomes. {ECO:0000269|PubMed:17289661}. |
Top Pathways | Spliceosome |
Human hnRNP U peptide - ab21993 from Abcam
|
||||||||||
Human hnRNP U protein fragment - ab152451 from Abcam
|
||||||||||
HnRNP U Antibody Blocking Peptide - LS-E14800 from LifeSpan Bioscience
|
||||||||||
HnRNP U Antibody Blocking Peptide - LS-E14801 from LifeSpan Bioscience
|
||||||||||
hnRNP U Partial Recombinant Protein - H00003192-Q01 from Novus Biologicals
|
||||||||||
HNRNPU Blocking Peptide - 33R-6695 from Fitzgerald
|
||||||||||
HNRNPU Blocking Peptide - 33R-2489 from Fitzgerald
|
||||||||||
hnRNP-U / HNRNPU - H00003192-Q01-10 from Acris Antibodies
|
||||||||||
hnRNP-U / HNRNPU - H00003192-Q01-25 from Acris Antibodies
|
||||||||||
HNRNPU fusion protein - ag9151 from Proteintech Group
|
||||||||||
HNRNPU fusion protein - ag9144 from Proteintech Group
|
||||||||||
HNRNPU fusion protein - Ag6141 from Proteintech Group
|
||||||||||
Recombinant Heterogeneous Nuclear Ribonucleoprotein U (HNRPU) - RPF128Hu01 from Uscn Life Science Inc.
|
||||||||||
Recombinant Heterogeneous Nuclear Ribonucleoprotein U (HNRPU) - RPF128Hu01 from Cloud-clone
|
||||||||||
hnRNP-U / HNRNPU (transcript variant 2) - TP301627 from Acris Antibodies
|
||||||||||
hnRNP U Recombinant Protein Antigen - NBP2-49290PEP from Novus Biologicals
|
||||||||||
hnRNP U Recombinant Protein Antigen - NBP2-48729PEP from Novus Biologicals
|
||||||||||
HNRNPU-Blocking-Peptide-C-term - BP21212b from Abgent, a WuXi AppTec company
|
||||||||||
HNRNPU Peptide, Human - M34GP07166H from Creative Peptides
|