Gene Symbol | GTF2A1L |
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Entrez Gene | 11036 |
Alt Symbol | ALF |
Species | Human |
Gene Type | protein-coding |
Description | general transcription factor IIA, 1-like |
Other Description | GTF2A1-like factor|TFIIA large subunit isoform ALF|TFIIA-alpha and beta-like factor|TFIIA-alpha/beta-like factor|general transcription factor II A, 1-like factor |
Swissprots | Q53FD9 B4DY14 Q5D050 Q9UNN4 |
Accessions | EAX00193 EAX00194 Q9UNN4 AF106857 AAD39634 AI037906 AK223350 BAD97070 AK302220 BAG63576 BC025991 AAH25991 BC064585 AAH64585 BG207854 BG717289 DQ891566 ABM82492 DQ894756 ABM85682 HY049561 NM_001193487 NP_001180416 NM_006872 NP_006863 NM_172196 |
Function | May function as a testis specific transcription factor. Binds DNA in conjunction with GTF2A2 and TBP (the TATA-binding protein) and together with GTF2A2, allows mRNA transcription. {ECO:0000269|PubMed:10364255}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:16525715}. Note=Mainly localizes in the annulus and partly in acrosomal cap area of spermatozoa. |
Tissue Specificity | Testis specific. Detected in adult testis mostly in round and elongating spermatids (at protein level). Detected in testis. {ECO:0000269|PubMed:10364255, ECO:0000269|PubMed:16525715}. |
Top Pathways | Viral carcinogenesis, Basal transcription factors |
ALF (H-57) - sc-292178 from Santa Cruz Biotechnology
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ALF (L-20) - sc-68946 from Santa Cruz Biotechnology
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ALF (N-20) - sc-68947 from Santa Cruz Biotechnology
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ALF (24) - sc-130304 from Santa Cruz Biotechnology
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Anti-ALF antibody - ab56842 from Abcam
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Anti-ALF antibody - ab22882 from Abcam
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Anti-ALF antibody - ab123300 from Abcam
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Anti-ALF antibody - ab197207 from Abcam
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Anti-ALF antibody - ab56839 from Abcam
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Anti-GTF2A1L / ALF Antibody (aa86-135) - LS-C30433 from LifeSpan Bioscience
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Anti-GTF2A1L / ALF Antibody (aa86-135) - LS-C31080 from LifeSpan Bioscience
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Anti-GTF2A1L / ALF Antibody (C-Terminus) - LS-C30550 from LifeSpan Bioscience
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Anti-GTF2A1L / ALF Antibody (aa398-428, AP) - LS-C236017 from LifeSpan Bioscience
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Anti-GTF2A1L / ALF Antibody (aa337-386) - LS-C81606 from LifeSpan Bioscience
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Anti-GTF2A1L / ALF Antibody (aa398-428, Biotin) - LS-C236019 from LifeSpan Bioscience
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Anti-GTF2A1L / ALF Antibody (aa398-428, APC) - LS-C236018 from LifeSpan Bioscience
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Anti-GTF2A1L / ALF Antibody - LS-C137528 from LifeSpan Bioscience
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Anti-GTF2A1L / ALF Antibody (aa398-428, FITC) - LS-C236020 from LifeSpan Bioscience
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Anti-GTF2A1L / ALF Antibody (aa398-428, PE) - LS-C236021 from LifeSpan Bioscience
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Anti-GTF2A1L / ALF Antibody (aa398-428, Azide-free, HRP) - LS-C249144 from LifeSpan Bioscience
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Anti-GTF2A1L / ALF Antibody (aa251-349) - LS-C306201 from LifeSpan Bioscience
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Anti-GTF2A1L / ALF Antibody - LS-C308145 from LifeSpan Bioscience
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Anti-GTF2A1L / ALF Antibody - LS-C310547 from LifeSpan Bioscience
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Anti-GTF2A1L / ALF Antibody (aa371-420) - LS-C135310 from LifeSpan Bioscience
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Anti-GTF2A1L / ALF Antibody (aa351-400) - LS-C135309 from LifeSpan Bioscience
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