| Gene Symbol |
TMPRSS4
|
| Entrez Gene |
56649
|
| Alt Symbol |
CAPH2, MT-SP2, TMPRSS3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
transmembrane protease, serine 4
|
| Other Description |
channel-activating protease 2|membrane-type serine protease 2|transmembrane protease serine 4|transmembrane serine protease 3|type II membrane serine protease
|
| Swissprots |
B7Z8C5 Q9NRS4 E7ERX8 A8MU84 Q6UX37 Q5XKQ6 Q9NZA5 B0YJB0
|
| Accessions |
ACA06088 EAW67345 EAW67346 EAW67347 EAW67348 EAW67349 EAW67350 Q9NRS4 AF179224 AAF74526 AF216312 AAF31436 AK172766 BAD18749 AK290361 BAF83050 AK296855 BAH12444 AK303173 BAH13911 AK304113 BAH14107 AK304215 BAH14136 AK308434 AK311290 AY358530 AAQ88894 BC004855 AAH04855 BC011703 AAH11703 BC012752 BE736425 BP220493 BU685753 HQ447915 ADQ32399 XM_005271613 XP_005271670 XM_005271614 XP_005271671 XM_005271615 XP_005271672 XM_011542901 XP_011541203 XM_011542902 XP_011541204 XM_011542903 XP_011541205 XM_011542904 XP_011541206 NM_001083947 NP_001077416 NM_001173551 NP_001167022 NM_001173552 NP_001167023 NM_001290094 NP_001277023 NM_001290096 NP_001277025 NM_019894 NP_063947 NR_110734 NM_183247
|
| Function |
Probable protease. Seems to be capable of activating ENaC (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
|
| Tissue Specificity |
High levels in pancreatic, gastric, colorectal and ampullary cancer. Very weak expression in normal gastrointestinal and urogenital tract.
|
| Top Pathways |
Influenza A
|
![Western Blot: TMPRSS4 Overexpression Lysate (Adult Normal) [NBP2-10066] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for TMPRSS4.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/6575_TMPRSS4%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-10066-img0001.jpg)