Gene Symbol | TMPRSS4 |
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Entrez Gene | 56649 |
Alt Symbol | CAPH2, MT-SP2, TMPRSS3 |
Species | Human |
Gene Type | protein-coding |
Description | transmembrane protease, serine 4 |
Other Description | channel-activating protease 2|membrane-type serine protease 2|transmembrane protease serine 4|transmembrane serine protease 3|type II membrane serine protease |
Swissprots | B7Z8C5 Q9NRS4 E7ERX8 A8MU84 Q6UX37 Q5XKQ6 Q9NZA5 B0YJB0 |
Accessions | ACA06088 EAW67345 EAW67346 EAW67347 EAW67348 EAW67349 EAW67350 Q9NRS4 AF179224 AAF74526 AF216312 AAF31436 AK172766 BAD18749 AK290361 BAF83050 AK296855 BAH12444 AK303173 BAH13911 AK304113 BAH14107 AK304215 BAH14136 AK308434 AK311290 AY358530 AAQ88894 BC004855 AAH04855 BC011703 AAH11703 BC012752 BE736425 BP220493 BU685753 HQ447915 ADQ32399 XM_005271613 XP_005271670 XM_005271614 XP_005271671 XM_005271615 XP_005271672 XM_011542901 XP_011541203 XM_011542902 XP_011541204 XM_011542903 XP_011541205 XM_011542904 XP_011541206 NM_001083947 NP_001077416 NM_001173551 NP_001167022 NM_001173552 NP_001167023 NM_001290094 NP_001277023 NM_001290096 NP_001277025 NM_019894 NP_063947 NR_110734 NM_183247 |
Function | Probable protease. Seems to be capable of activating ENaC (By similarity). {ECO:0000250}. |
Subcellular Location | Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}. |
Tissue Specificity | High levels in pancreatic, gastric, colorectal and ampullary cancer. Very weak expression in normal gastrointestinal and urogenital tract. |
Top Pathways | Influenza A |
TMPRSS3 Antibody Blocking Peptide - LS-E21064 from LifeSpan Bioscience
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TMPRSS3 Antibody Blocking Peptide - LS-E21063 from LifeSpan Bioscience
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TMPRSS3 Antibody Blocking Peptide - LS-E26531 from LifeSpan Bioscience
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TMPRSS3 Antibody Blocking Peptide - LS-E8560 from LifeSpan Bioscience
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TMPRSS3 Antibody Blocking Peptide - LS-E23959 from LifeSpan Bioscience
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TMPRSS4 Antibody Blocking Peptide - LS-E29481 from LifeSpan Bioscience
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TMPRSS4 Antibody Blocking Peptide - LS-E17852 from LifeSpan Bioscience
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TMPRSS4 Antibody Blocking Peptide - LS-E26590 from LifeSpan Bioscience
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TMPRSS4 Antibody Blocking Peptide - LS-E26591 from LifeSpan Bioscience
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TMPRSS4 Antibody Blocking Peptide - LS-E29808 from LifeSpan Bioscience
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TMPRSS4 Antibody Blocking Peptide - LS-E29807 from LifeSpan Bioscience
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TMPRSS4 Antibody Blocking Peptide - LS-E29810 from LifeSpan Bioscience
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TMPRSS3 blocking peptide - GTX88931-PEP from GeneTex
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TMPRSS4 (aa245-57) blocking peptide - GTX47593-PEP from GeneTex
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TMPRSS4 blocking peptide - GTX88636-PEP from GeneTex
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TMPRSS4 Immunizing peptide - orb55102 from Biorbyt
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TMPRSS3 Blocking Peptide - 33R-6022 from Fitzgerald
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TMPRSS3 Blocking Peptide - 33R-6021 from Fitzgerald
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TMPRSS4 Blocking Peptide - 33R-5428 from Fitzgerald
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TMPRSS4 Blocking Peptide - 33R-4099 from Fitzgerald
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TMPRSS4 Peptide - AC21-1426-P from Abcore
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TMPRSS4 Peptide - AC21-1427-P from Abcore
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TMPRSS4 Peptide - 46-909P from ProSci
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TMPRSS4 Peptide - 42-029P from ProSci
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TMPRSS4 fusion protein - Ag1804 from Proteintech Group
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