TMPRSS4

Gene Symbol TMPRSS4
Entrez Gene 56649
Alt Symbol CAPH2, MT-SP2, TMPRSS3
Species Human
Gene Type protein-coding
Description transmembrane protease, serine 4
Other Description channel-activating protease 2|membrane-type serine protease 2|transmembrane protease serine 4|transmembrane serine protease 3|type II membrane serine protease
Swissprots B7Z8C5 Q9NRS4 E7ERX8 A8MU84 Q6UX37 Q5XKQ6 Q9NZA5 B0YJB0
Accessions ACA06088 EAW67345 EAW67346 EAW67347 EAW67348 EAW67349 EAW67350 Q9NRS4 AF179224 AAF74526 AF216312 AAF31436 AK172766 BAD18749 AK290361 BAF83050 AK296855 BAH12444 AK303173 BAH13911 AK304113 BAH14107 AK304215 BAH14136 AK308434 AK311290 AY358530 AAQ88894 BC004855 AAH04855 BC011703 AAH11703 BC012752 BE736425 BP220493 BU685753 HQ447915 ADQ32399 XM_005271613 XP_005271670 XM_005271614 XP_005271671 XM_005271615 XP_005271672 XM_011542901 XP_011541203 XM_011542902 XP_011541204 XM_011542903 XP_011541205 XM_011542904 XP_011541206 NM_001083947 NP_001077416 NM_001173551 NP_001167022 NM_001173552 NP_001167023 NM_001290094 NP_001277023 NM_001290096 NP_001277025 NM_019894 NP_063947 NR_110734 NM_183247
Function Probable protease. Seems to be capable of activating ENaC (By similarity). {ECO:0000250}.
Subcellular Location Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Tissue Specificity High levels in pancreatic, gastric, colorectal and ampullary cancer. Very weak expression in normal gastrointestinal and urogenital tract.
Top Pathways Influenza A

TMPRSS4 (A-3) - sc-376415 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
TMPRSS4 (A-3): sc-376415. Immunoperoxidase staining of formalin fixed, paraffin-embedded human adrenal gland tissue showing cytoplasmic staining of glandular cells.

TMPRSS4 (D-17) - sc-66599 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

TMPRSS4 (D-1) - sc-390875 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
TMPRSS4 (D-1): sc-390875. Western blot analysis of TMPRSS4 expression in human pancreas tissue extract.

TMPRSS4 (M-216) - sc-135094 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

TMPRSS4 (N-17) - sc-66600 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-TMPRSS3 antibody - ab24158 from Abcam

Prices $370.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-TMPRSS3 antibody (ab24158)Lane 1 : total extract from 293T cells transfected with pHATMPRSS3Lane 2 : total extract from 293T cells transfected with pHA (empty vector)Lysates/proteins at 40 µg per lane.

Anti-TMPRSS4 antibody - ab133954 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-TMPRSS4 antibody (ab133954) at 1 µg/mlLane 1 : Colon tissue lysate (Human) Tissue Lysate - adult normal tissue (ab30051)Lane 2 : PANC-1 (Human Pancreatic Carcinoma) Whole Cell LysateLane 3 : SW480 (Human colon adenocarcinoma cell line) Whole Cell LysateLane 4 : Caco 2 (Human colonic carcinoma cell line) Whole Cell LysateLane 5 : HCT 116 (Human Colorectal Carcinoma) Whole Cell LysateLysates/proteins at 10 µg per lane.SecondaryGoat Anti-Rabbit IgG H&L (HRP) (ab97051) at 1/10000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-TMPRSS4 antibody - ab56117 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-TMPRSS4 antibody (ab56117) at 1/1000 dilutionLane 1 : Tissue lysate from mouse pancreasLane 2 : Tissue lysate from mouse pancreasLane 3 : Tissue lysate from mouse pancreasLane 4 : Whole cell lysate prepared from Madin Darby canine kidney (MDCK) cellsLane 5 : Whole cell lysate prepared from Madin Darby canine kidney (MDCK) cellsLane 6 : Whole cell lysate prepared from Madin Darby canine kidney (MDCK) cells

Anti-TMPRSS4 antibody - ab56119 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-TMPRSS4 antibody (ab56119) at 1/1000 dilutionLane 1 : Tissue lysate from rat lungLane 2 : Tissue lysate from rat lung

Anti-TMPRSS4 antibody - ab56120 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-TMPRSS4 antibody (ab56120) at 1/1000 dilutionLane 1 : Whole cell lysate from human epithelial carcinoma A431 cells Lane 2 : Whole cell lysate from human epithelial carcinoma A431 cells

Anti-TMPRSS4 antibody - ab82176 from Abcam

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Anti-TMPRSS4 antibody (ab82176) at 1 µg/ml + Human Bone Marrow lysate (in RIPA buffer) at 35 µgdeveloped using the ECL technique

Anti-TMPRSS4 Antibody (Internal) IHC-plus™ - LS-A9910 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-TMPRSS4 antibody LS-A9910 IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-TMPRSS4 Antibody (Internal) IHC-plus™ - LS-A8773 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-TMPRSS4 antibody IHC of human Pancreas, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-TMPRSS4 Antibody (Internal) IHC-plus™ - LS-A9908 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-TMPRSS4 antibody LS-A9908 IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-TMPRSS4 Antibody (N-Terminus) IHC-plus™ - LS-A9909 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-TMPRSS4 antibody LS-A9909 IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-TMPRSS4 Antibody (aa71-120) IHC-plus™ - LS-B11941 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)

Anti-TMPRSS4 Antibody (aa243-255) - LS-C112809 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
TMPRSS4 antibody (1 ug/ml) staining of HEK293 lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-TMPRSS4 Antibody (aa350-363) - LS-C87235 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Antibody (1 ug/ml) staining of Human Bone Marrow lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence

Anti-TMPRSS4 Antibody (aa179-228) - LS-C116372 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
TMPRSS4 antibody LS-C116372 Western blot of HepG2 cell lysate.

TMPRSS4 Antibody - NBP1-56991 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: TMPRSS4 Antibody [NBP1-56991] - HepG2 cell lysate, concentration 0.2-1 ug/ml.

TMPRSS4 Antibody - NBP1-82608 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: TMPRSS4 Antibody [NBP1-82608] - Staining of human urinary bladder shows cytoplasmic positivity in urothelial cells.

TMPRSS3 Antibody - NBP1-85240 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: TMPRSS3 Antibody [NBP1-85240] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11<br/>Lane 2: Human cell line RT-4<br/>Lane 3: Human cell line U-251MG sp<br/>Lane 4: Human plasma (IgG/HSA depleted)<br/>Lane 5: Human liver tissue<br/>Lane 6: Human tonsil tissue

TMPRSS4 Antibody - NBP1-50175 from Novus Biologicals

Prices $329.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

TMPRSS4 Antibody - NBP1-20985 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot: TMPRSS4 Antibody [NBP1-20985] - (1ug/ml) staining of Human Bone Marrow lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

TMPRSS4 Antibody - NBP1-36997 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot: TMPRSS4 Antibody [NBP1-36997] - Analysis of TMPRSS4 in HEK293 lysate (35ug protein in RIPA buffer) using this antibody at 1ug/ml. Primary incubation was 1 hour. Detected by chemiluminescence.
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