P2RX2

Gene Symbol	P2RX2
Entrez Gene	22953
Alt Symbol	DFNA41, P2X2
Species	Human
Gene Type	protein-coding
Description	purinergic receptor P2X, ligand gated ion channel, 2
Other Description	ATP receptor|P2X Receptor, subunit 2|P2X purinoceptor 2|purinergic receptor P2X, ligand-gated ion channel, 2
Swissprots	Q9UHD6 Q9NR37 A6NHC2 A6NIG9 A6NH93 Q9UHD5 Q9UHD7 A6NGB4 Q9Y638 Q9NR38 Q9Y637 Q9UBL9 A6NHU3 Q6V9R6
Accessions	AAF19174 EAW54835 EAW54836 EAW54837 EAW54838 EAW54839 EAW54840 Q9UBL9 AF109387 AAD42947 AF109388 AAD42948 AF190822 AAF19170 AF190823 AAF19171 AF190824 AAF19172 AF190825 AAF19173 AF260426 AAF74201 AF260427 AAF74202 AF260428 AAF74203 AF260429 AAF74204 AY346374 AAQ54329 BC109200 AAI09201 HQ323686 XM_005266154 XP_005266211 XM_005266155 XP_005266212 XM_005266156 XP_005266213 XM_011534786 XP_011533088 NM_001282164 NP_001269093 NM_001282165 NP_001269094 NM_012226 NP_036358 NM_016318 NP_057402 NM_170682 NP_733782 NM_170683 NP_733783 NM_174872 NP_777361 NM_174873 NP_777362
Function	Ion channel gated by extracellular ATP involved in a variety of cellular responses, such as excitatory postsynaptic responses in sensory neurons, neuromuscular junctions (NMJ) formation, hearing, perception of taste and peristalsis. In the inner ear, regulates sound transduction and auditory neurotransmission, outer hair cell electromotility, inner ear gap junctions, and K(+) recycling. Mediates synaptic transmission between neurons and from neurons to smooth muscle. {ECO:0000269|PubMed:23345450}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:23345450}; Multi-pass membrane protein {ECO:0000269|PubMed:23345450}. Note=Localizes to the apical membranes of hair cells in the organ of Corti.
Top Pathways	Calcium signaling pathway, Neuroactive ligand-receptor interaction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human P2X2 full length protein - ab132031 from Abcam Category Protein Source Wheat germ Species Human

Human P2X2 peptide - ab95915 from Abcam Category Peptide Species Human

Human P2X2 protein fragment - ab153197 from Abcam Category Protein Source Wheat germ Species Human

P2X2 peptide - ab38196 from Abcam Category Peptide

P2RX2 / P2X2 Antibody Blocking Peptide - LS-E3833 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

P2RX2 / P2X2 Antibody Blocking Peptide - LS-E12598 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

P2RX2 / P2X2 Blocking Peptide - LS-E12599 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

P2RX2 / P2X2 Antibody Blocking Peptide - LS-E12600 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

P2RX2 / P2X2 Antibody Blocking Peptide - LS-E12601 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

P2RX2 / P2X2 Antibody Blocking Peptide - LS-E12523 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

P2RX2 / P2X2 Antibody Blocking Peptide - LS-E12524 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

P2RX2 / P2X2 Antibody Blocking Peptide - LS-E12541 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

P2RX2 / P2X2 Antibody Blocking Peptide - LS-E12540 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

P2RX2 / P2X2 Antibody Blocking Peptide - LS-E12633 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

P2RX2 / P2X2 Antibody Blocking Peptide - LS-E12634 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human P2X2/P2RX2 Protein - H00022953-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human P2X2/P2RX2 Protein - H00022953-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

P2RX2-Antibody-N-term-Blocking-Peptide - BP16011a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

P2RX2 Blocking Peptide - 33R-1942 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

P2rx2 Blocking Peptide - 33R-10318 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

P2RX2 Blocking Peptide - 33R-4132 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

P2RX2 Blocking Peptide - 33R-7540 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

P2RX2 Blocking Peptide - 33R-9779 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

P2RX2 Blocking Peptide - 33R-5050 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

P2RX2 Blocking Peptide - 33R-1943 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

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