Gene Symbol | CROCC |
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Entrez Gene | 9696 |
Alt Symbol | ROLT |
Species | Human |
Gene Type | protein-coding |
Description | ciliary rootlet coiled-coil, rootletin |
Other Description | Tax1-binding protein 2|ciliary rootlet coiled-coil protein|rootletin|rootletin, ciliary rootlet protein |
Swissprots | Q5TZA2 Q7Z5D7 Q7Z2L4 Q2VHY3 Q66GT7 |
Accessions | EAW94814 EAW94815 EAW94816 EAW94817 Q5TZA2 AB007914 BAA32290 AF527734 AAP85633 AK026910 BC126911 AAI26912 BC126912 AAI26913 BK005505 DAA05505 BM678006 DQ139275 ABA43896 XM_006711058 XP_006711121 XM_011542468 XP_011540770 XM_011542469 XP_011540771 XM_011542470 XP_011540772 XM_011542471 XP_011540773 XM_011542472 XP_011540774 NM_014675 NP_055490 |
Function | Major structural component of the ciliary rootlet, a cytoskeletal-like structure in ciliated cells which originates from the basal body at the proximal end of a cilium and extends proximally toward the cell nucleus. Contributes to centrosome cohesion before mitosis. {ECO:0000250|UniProtKB:Q8CJ40, ECO:0000269|PubMed:16203858}. |
Subcellular Location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269|PubMed:14654843}. Note=In ciliated cells, associated with ciliary rootlets. In non-ciliated cells, localized between, around and at the proximal ends of the centrioles. Dissociates from the centrioles at the onset of mitosis and reassociates with them at anaphase. |
Rootletin (C-2) - sc-374056 from Santa Cruz Biotechnology
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Rootletin (E-5) - sc-390720 from Santa Cruz Biotechnology
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Rootletin (C-20) - sc-67824 from Santa Cruz Biotechnology
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Rootletin (H-84) - sc-135275 from Santa Cruz Biotechnology
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Rootletin (Q-15) - sc-67828 from Santa Cruz Biotechnology
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Anti-CROCC antibody - ab121653 from Abcam
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Anti-CROCC antibody - ab121694 from Abcam
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CROCC Antibody - NBP1-80820 from Novus Biologicals
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CROCC Antibody - NBP1-80821 from Novus Biologicals
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Anti-CROCC antibody produced in rabbit - HPA021762 from Sigma-Aldrich
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Rabbit anti-Human CROCC polyclonal antibody - DPABH-19641 from Creative Diagnostics
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Rabbit anti-Human CROCC polyclonal antibody - DPABH-20012 from Creative Diagnostics
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Anti-CROCC antibody produced in rabbit - HPA021191 from Sigma-Aldrich
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CROCC antibody - orb338672 from Biorbyt
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CROCC antibody - orb182754 from Biorbyt
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Recombinant Anti-Human CROCC Antibody - MOB-3832z from Creative Biolabs
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Recombinant Anti-Human CROCC Antibody scFv Fragment - MOB-3832z-S(P) from Creative Biolabs
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Recombinant Anti-Human CROCC Antibody Fab Fragment - MOB-3832z-F(E) from Creative Biolabs
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CROCC Antibody - 46217 from Signalway Antibody
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CROCC Antibody - DF9876 from Affinity Biosciences
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TAX1BP2, Polyclonal Antibody - MBS417818 from MyBioSource
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CROCC antibody - orb399311 from Biorbyt
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CROCC antibody (FITC) - orb187067 from Biorbyt
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