CROCC

Gene Symbol CROCC
Entrez Gene 9696
Alt Symbol ROLT
Species Human
Gene Type protein-coding
Description ciliary rootlet coiled-coil, rootletin
Other Description Tax1-binding protein 2|ciliary rootlet coiled-coil protein|rootletin|rootletin, ciliary rootlet protein
Swissprots Q5TZA2 Q7Z5D7 Q7Z2L4 Q2VHY3 Q66GT7
Accessions EAW94814 EAW94815 EAW94816 EAW94817 Q5TZA2 AB007914 BAA32290 AF527734 AAP85633 AK026910 BC126911 AAI26912 BC126912 AAI26913 BK005505 DAA05505 BM678006 DQ139275 ABA43896 XM_006711058 XP_006711121 XM_011542468 XP_011540770 XM_011542469 XP_011540771 XM_011542470 XP_011540772 XM_011542471 XP_011540773 XM_011542472 XP_011540774 NM_014675 NP_055490
Function Major structural component of the ciliary rootlet, a cytoskeletal-like structure in ciliated cells which originates from the basal body at the proximal end of a cilium and extends proximally toward the cell nucleus. Contributes to centrosome cohesion before mitosis. {ECO:0000250|UniProtKB:Q8CJ40, ECO:0000269|PubMed:16203858}.
Subcellular Location Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269|PubMed:14654843}. Note=In ciliated cells, associated with ciliary rootlets. In non-ciliated cells, localized between, around and at the proximal ends of the centrioles. Dissociates from the centrioles at the onset of mitosis and reassociates with them at anaphase.

Human CROCC ORF clone(NM_014675.3) - CDCH384163 from Creative biogene

Species Human
Search more