Gene Symbol |
CROCC
|
Entrez Gene |
9696
|
Alt Symbol |
ROLT
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
ciliary rootlet coiled-coil, rootletin
|
Other Description |
Tax1-binding protein 2|ciliary rootlet coiled-coil protein|rootletin|rootletin, ciliary rootlet protein
|
Swissprots |
Q5TZA2 Q7Z5D7 Q7Z2L4 Q2VHY3 Q66GT7
|
Accessions |
EAW94814 EAW94815 EAW94816 EAW94817 Q5TZA2 AB007914 BAA32290 AF527734 AAP85633 AK026910 BC126911 AAI26912 BC126912 AAI26913 BK005505 DAA05505 BM678006 DQ139275 ABA43896 XM_006711058 XP_006711121 XM_011542468 XP_011540770 XM_011542469 XP_011540771 XM_011542470 XP_011540772 XM_011542471 XP_011540773 XM_011542472 XP_011540774 NM_014675 NP_055490
|
Function |
Major structural component of the ciliary rootlet, a cytoskeletal-like structure in ciliated cells which originates from the basal body at the proximal end of a cilium and extends proximally toward the cell nucleus. Contributes to centrosome cohesion before mitosis. {ECO:0000250|UniProtKB:Q8CJ40, ECO:0000269|PubMed:16203858}.
|
Subcellular Location |
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269|PubMed:14654843}. Note=In ciliated cells, associated with ciliary rootlets. In non-ciliated cells, localized between, around and at the proximal ends of the centrioles. Dissociates from the centrioles at the onset of mitosis and reassociates with them at anaphase.
|