Gene Symbol | CXCL1 |
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Entrez Gene | 2919 |
Alt Symbol | FSP, GRO1, GROa, MGSA, MGSA-a, NAP-3, SCYB1 |
Species | Human |
Gene Type | protein-coding |
Description | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) |
Other Description | C-X-C motif chemokine 1|GRO-alpha(1-73)|GRO1 oncogene (melanoma growth stimulating activity, alpha)|GRO1 oncogene (melanoma growth-stimulating activity)|MGSA alpha|fibroblast secretory protein|growth-regulated alpha protein|melanoma growth stimulatory activity alpha|neutrophil-activating protein 3 |
Swissprots | P09341 Q9UCR7 |
Accessions | AAA03452 AAP13103 CAA38361 CBX54348 CCD62019 EAX05693 P09341 BC011976 AAH11976 BG121608 BM554448 BM996663 BQ000742 BT006880 AAP35526 CB112830 DQ893591 ABM84517 DQ894941 ABM85867 J03561 AAA35933 X12510 CAA31027 NM_001511 NP_001502 NR_046035 |
Function | Has chemotactic activity for neutrophils. May play a role in inflammation and exerts its effects on endothelial cells in an autocrine fashion. In vitro, the processed forms GRO- alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) show a 30-fold higher chemotactic activity. {ECO:0000269|PubMed:10095777}. |
Subcellular Location | Secreted. |
Top Pathways | TNF signaling pathway, Cytokine-cytokine receptor interaction, Legionellosis, Salmonella infection, Rheumatoid arthritis |
GROα (G-7) - sc-514065 from Santa Cruz Biotechnology
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GROα (5G11) - sc-130316 from Santa Cruz Biotechnology
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GROα (C-15) - sc-1374 from Santa Cruz Biotechnology
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GROα/β/γ (FL-100) - sc-28972 from Santa Cruz Biotechnology
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Anti-GRO alpha antibody - ab86436 from Abcam
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Anti-GRO alpha antibody - ab10376 from Abcam
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Anti-GRO alpha antibody [EPR4902] - ab124898 from Abcam
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Anti-GRO alpha antibody [EPR4903] - ab124731 from Abcam
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Anti-GRO alpha antibody [MM0208-9A18] - ab89318 from Abcam
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Anti-GRO / CXCL1 Antibody - LS-C6266 from LifeSpan Bioscience
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Anti-GRO / CXCL1 Antibody - LS-C87021 from LifeSpan Bioscience
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Anti-GRO / CXCL1 Antibody (aa35-107) - LS-C67127 from LifeSpan Bioscience
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Anti-GRO / CXCL1 Antibody (C-Terminus) - LS-C30065 from LifeSpan Bioscience
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Anti-GRO / CXCL1 Antibody (Biotin) - LS-C104613 from LifeSpan Bioscience
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Anti-GRO / CXCL1 Antibody (aa36-107, clone 7A11) - LS-C125418 from LifeSpan Bioscience
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Anti-GRO / CXCL1 Antibody - LS-C48831 from LifeSpan Bioscience
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Anti-GRO / CXCL1 Antibody (aa36-107) - LS-C137618 from LifeSpan Bioscience
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Anti-GRO / CXCL1 Antibody (C-Terminus) - LS-C108147 from LifeSpan Bioscience
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Anti-GRO / CXCL1 Antibody - LS-C193997 from LifeSpan Bioscience
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Anti-GRO / CXCL1 Antibody - LS-C193998 from LifeSpan Bioscience
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Anti-GRO / CXCL1 Antibody (N-Terminus) - LS-C193999 from LifeSpan Bioscience
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Anti-GRO / CXCL1 Antibody (aa39-88) - LS-C199875 from LifeSpan Bioscience
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Anti-GRO / CXCL1 Antibody (clone 2D7) - LS-C139335 from LifeSpan Bioscience
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Anti-GRO / CXCL1 Antibody (Internal, clone EPR4903) - LS-C138715 from LifeSpan Bioscience
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Anti-GRO / CXCL1 Antibody (clone 6G2) - LS-C200925 from LifeSpan Bioscience
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