| Gene Symbol |
CXCL1
|
| Entrez Gene |
2919
|
| Alt Symbol |
FSP, GRO1, GROa, MGSA, MGSA-a, NAP-3, SCYB1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
|
| Other Description |
C-X-C motif chemokine 1|GRO-alpha(1-73)|GRO1 oncogene (melanoma growth stimulating activity, alpha)|GRO1 oncogene (melanoma growth-stimulating activity)|MGSA alpha|fibroblast secretory protein|growth-regulated alpha protein|melanoma growth stimulatory activity alpha|neutrophil-activating protein 3
|
| Swissprots |
P09341 Q9UCR7
|
| Accessions |
AAA03452 AAP13103 CAA38361 CBX54348 CCD62019 EAX05693 P09341 BC011976 AAH11976 BG121608 BM554448 BM996663 BQ000742 BT006880 AAP35526 CB112830 DQ893591 ABM84517 DQ894941 ABM85867 J03561 AAA35933 X12510 CAA31027 NM_001511 NP_001502 NR_046035
|
| Function |
Has chemotactic activity for neutrophils. May play a role in inflammation and exerts its effects on endothelial cells in an autocrine fashion. In vitro, the processed forms GRO- alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) show a 30-fold higher chemotactic activity. {ECO:0000269|PubMed:10095777}.
|
| Subcellular Location |
Secreted.
|
| Top Pathways |
TNF signaling pathway, Cytokine-cytokine receptor interaction, Legionellosis, Salmonella infection, Rheumatoid arthritis
|
![Western Blot: GRO alpha Overexpression Lysate (Adult Normal) [NBP2-10978] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for GRO alpha.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/3759_GRO%2520alpha%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-10978-img0001.jpg)