Gene Symbol | Fgf8 |
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Entrez Gene | 14179 |
Alt Symbol | Aigf, Fgf-8 |
Species | Mouse |
Gene Type | protein-coding |
Description | fibroblast growth factor 8 |
Other Description | HBGF-8|androgen-induced growth factor|heparin-binding growth factor 8 |
Swissprots | P37237 |
Accessions | AAA61908 EDL41963 EDL41964 EDL41965 EDL41966 P37237 AK131980 BAE20919 BC048734 AAH48734 BU512456 D12482 BAA02050 D12483 BAA02051 HQ260698 AEN94297 U18673 AAA65387 Z48746 CAA88637 XM_006526668 XP_006526731 XM_011247142 XP_011245444 XM_011247143 XP_011245445 NM_001166361 NP_001159833 NM_001166362 NP_001159834 NM_001166363 NP_001159835 NM_010205 NP_034335 |
Function | Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. Required for normal brain, eye, ear and limb development during embryogenesis. Required for normal development of the gonadotropin-releasing hormone (GnRH) neuronal system. Plays a role in neurite outgrowth in hippocampal cells (By similarity). Cooperates with Wnt-1 in mouse mammary tumor virus- induced murine mammary tumorigenesis (PubMed:7884899). {ECO:0000250|UniProtKB:P55075}. |
Subcellular Location | Secreted. |
Tissue Specificity | Absent in normal mammary glands and detected only in adult testis and ovary and in midgestational embryos. |
Top Pathways | Melanoma, MAPK signaling pathway, PI3K-Akt signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton |
Anti-FGF8 antibody - N-terminal - ab174373 from Abcam
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Anti-FGF8 Antibody (aa30-59, APC) - LS-C214218 from LifeSpan Bioscience
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Anti-FGF8 Antibody (aa30-59, AP) - LS-C214217 from LifeSpan Bioscience
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Anti-FGF8 Antibody (aa30-59, FITC) - LS-C214219 from LifeSpan Bioscience
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Anti-FGF8 Antibody (aa30-59, Biotin) - LS-C214220 from LifeSpan Bioscience
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Anti-FGF8 Antibody (aa30-59, Azide-free, HRP) - LS-C214221 from LifeSpan Bioscience
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Anti-FGF8 Antibody (aa30-59, PE) - LS-C214222 from LifeSpan Bioscience
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Anti-FGF8 Antibody (aa30-59) - LS-C321369 from LifeSpan Bioscience
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Anti-FGF8 Antibody (aa30-59) - LS-C157912 from LifeSpan Bioscience
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FGF-8 Antibody [Biotin] - BAF423 from Novus Biologicals
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FGF8 Polyclonal Antibody - bs-0735R from Bioss
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FGF8 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-0735R-A350 from Bioss
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FGF8 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-0735R-A488 from Bioss
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FGF8 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-0735R-A555 from Bioss
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FGF8 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-0735R-A647 from Bioss
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FGF8 Polyclonal Antibody, Cy3 Conjugated - bs-0735R-Cy3 from Bioss
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FGF8 Polyclonal Antibody, Cy5 Conjugated - bs-0735R-Cy5 from Bioss
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FGF8 Polyclonal Antibody, Cy5.5 Conjugated - bs-0735R-Cy5.5 from Bioss
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FGF8 Polyclonal Antibody, Cy7 Conjugated - bs-0735R-Cy7 from Bioss
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FGF8 Polyclonal Antibody, FITC Conjugated - bs-0735R-FITC from Bioss
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FGF8 Polyclonal Antibody, Biotin Conjugated - bs-0735R-Biotin from Bioss
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FGF8 Polyclonal Antibody, HRP Conjugated - bs-0735R-HRP from Bioss
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Mouse-Fgf8-AntibodyN-term - AP19631a from Abgent, a WuXi AppTec company
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Mouse Fgf8 Antibody - N-terminal region (OAAB15154) - OAAB15154 from Aviva Systems Biology
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FGF8 Antibody (OABF00273) - OABF00273 from Aviva Systems Biology
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