| Gene Symbol | Fgf8 |
|---|---|
| Entrez Gene | 14179 |
| Alt Symbol | Aigf, Fgf-8 |
| Species | Mouse |
| Gene Type | protein-coding |
| Description | fibroblast growth factor 8 |
| Other Description | HBGF-8|androgen-induced growth factor|heparin-binding growth factor 8 |
| Swissprots | P37237 |
| Accessions | AAA61908 EDL41963 EDL41964 EDL41965 EDL41966 P37237 AK131980 BAE20919 BC048734 AAH48734 BU512456 D12482 BAA02050 D12483 BAA02051 HQ260698 AEN94297 U18673 AAA65387 Z48746 CAA88637 XM_006526668 XP_006526731 XM_011247142 XP_011245444 XM_011247143 XP_011245445 NM_001166361 NP_001159833 NM_001166362 NP_001159834 NM_001166363 NP_001159835 NM_010205 NP_034335 |
| Function | Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. Required for normal brain, eye, ear and limb development during embryogenesis. Required for normal development of the gonadotropin-releasing hormone (GnRH) neuronal system. Plays a role in neurite outgrowth in hippocampal cells (By similarity). Cooperates with Wnt-1 in mouse mammary tumor virus- induced murine mammary tumorigenesis (PubMed:7884899). {ECO:0000250|UniProtKB:P55075}. |
| Subcellular Location | Secreted. |
| Tissue Specificity | Absent in normal mammary glands and detected only in adult testis and ovary and in midgestational embryos. |
| Top Pathways | Melanoma, MAPK signaling pathway, PI3K-Akt signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton |
Mouse Fgf8 cDNA clone(NM_001166363.1) - CDFG020809 from Creative Biomart
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Mouse Fgf8 cDNA clone(NM_001166362.1) - CDFG020810 from Creative Biomart
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Mouse Fgf8 cDNA clone(NM_010205.2) - CDFL004652 from Creative Biomart
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Human Fgf8 ORF clone - CDCL108115 from Creative Biomart
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Human Fgf8 ORF clone - CDCL108116 from Creative Biomart
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Human Fgf8 ORF clone - CDCL108117 from Creative Biomart
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Human Fgf8 ORF clone - CDCL108118 from Creative Biomart
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Human Fgf8 ORF clone - CDCL108119 from Creative Biomart
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Human Fgf8 ORF clone - CDCL108120 from Creative Biomart
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Human Fgf8 ORF clone - CDCL108121 from Creative Biomart
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Human Fgf8 ORF clone - CDCL108122 from Creative Biomart
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Mouse Fgf8 ORF Clone(NM_001166361.1) - CDCR241016 from Creative Biomart
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Mouse Fgf8 ORF Clone(NM_001166362.1) - CDCR241017 from Creative Biomart
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Mouse Fgf8 ORF Clone(NM_001166362.1) - CDCR241018 from Creative Biomart
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Mouse Fgf8 ORF Clone(NM_001166363.1) - CDCR241019 from Creative Biomart
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Mouse Fgf8 ORF Clone(NM_001166363.1) - CDCR241020 from Creative Biomart
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Mouse Fgf8 ORF Clone(NM_010205.2) - CDCR248625 from Creative Biomart
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Mouse Fgf8 ORF Clone(NM_010205.2) - CDCR248626 from Creative Biomart
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Mouse Fgf8 ORF clone(NM_001166361.1) - CDCL184258 from Creative Biomart
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Mouse Fgf8 Gene ORF cDNA clone expression plasmid, N-Flag tag - MG51101-NF from Sino Biological
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Mouse Fgf8 Gene ORF cDNA clone expression plasmid, C-His tag - MG51101-CH from Sino Biological
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Mouse Fgf8 Gene ORF cDNA clone expression plasmid, C-Flag tag - MG51101-CF from Sino Biological
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Mouse Fgf8 Gene ORF cDNA clone expression plasmid, C-HA tag - MG51101-CY from Sino Biological
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Mouse Fgf8 Gene ORF cDNA clone expression plasmid, N-Myc tag - MG51101-NM from Sino Biological
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Mouse Fgf8 Gene ORF cDNA clone expression plasmid, C-Myc tag - MG51101-CM from Sino Biological
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