CHD1L

Gene Symbol CHD1L
Entrez Gene 9557
Alt Symbol ALC1, CHDL
Species Human
Gene Type protein-coding
Description chromodomain helicase DNA binding protein 1-like
Other Description amplified in liver cancer 1|amplified in liver cancer protein 1|chromodomain-helicase-DNA-binding protein 1-like
Swissprots Q96HF7 Q6PK83 A5YM64 B5MDZ7 Q96SP3 Q86XH3 B4DDE1 Q53EZ3 Q9NVV8 Q86WJ1 Q5VXX7 Q9BVJ1 Q6DD94
Accessions CAH72650 EAW50936 EAW50937 EAW50938 Q86WJ1 AF054177 AAC39911 AF537213 AAO49505 AK001342 BAA91637 AK026183 BAB15386 AK027631 BAB55248 AK223496 BAD97216 AK293157 BAG56702 AK297135 BAG59638 AK298424 BAG60647 AK307400 BC001171 AAH01171 BC005038 AAH05038 BC008649 AAH08649 BC043501 AAH43501 BC053354 BC077717 AAH77717 BG195857 CB153921 CN255647 CN255649 CN255654 CR749729 DA007597 DA155685 DA745071 EC452903 EF560738 ABQ59048 KJ534809 AHW56449 R46126 XM_006711638 XP_006711701 XM_006711639 XP_006711702 XR_922001 NM_001256336 NP_001243265 NM_001256337 NP_001243266 NM_001256338 NP_001243267 NM_004284 NP_004275 NM_024568 NP_078844 NR_046070
Function DNA helicase which plays a role in chromatin-remodeling following DNA damage. Targeted to sites of DNA damage through interaction with poly(ADP-ribose) and functions to regulate chromatin during DNA repair. Able to catalyze nucleosome sliding in an ATP-dependent manner. Helicase activity is strongly stimulated upon poly(ADP-ribose)-binding. {ECO:0000269|PubMed:18023026, ECO:0000269|PubMed:19661379}.
Subcellular Location Nucleus {ECO:0000269|PubMed:19661379}. Note=Localizes at sites of DNA damage. Probably recruited to DNA damage sites by PARylated PARP1.
Tissue Specificity Frequently overexpressed in hepatomacellular carcinomas. {ECO:0000269|PubMed:18023026}.

CHD1L CRISPR/Cas9 KO Plasmid (h) - sc-404840 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CHD1L HDR Plasmid (h) - sc-404840-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CHD1L Double Nickase Plasmid (h) - sc-404840-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CHD1L Double Nickase Plasmid (h2) - sc-404840-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CHD1L CRISPR Activation Plasmid (h) - sc-404840-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CHD1L CRISPR Activation Plasmid (h2) - sc-404840-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CHD1L Lentiviral Activation Particles (h) - sc-404840-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CHD1L Lentiviral Activation Particles (h2) - sc-404840-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CHD1L siRNA (h) - sc-78807 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CHD1L shRNA Plasmid (h) - sc-78807-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CHD1L shRNA (h) Lentiviral Particles - sc-78807-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CHD1L RNAi - H00009557-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU065631 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN6041 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6041 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

CHD1L siRNA (Human) - CRH6358 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CHD1L - MBS8227767 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CHD1L CRISPR/Cas9 KO Plasmid (h2) - sc-404840-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CHD1L HDR Plasmid (h2) - sc-404840-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Human CHD1L siRNA - orb266860 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CHD1L shRNA Plasmid (Human) - CHH6358 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CHD1L miRNA 3'UTR clone - MiUTR3H-12734 from Creative biogene

Species Reactivities Human
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